Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Aspergillaceae 4

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00003008 External link 512 Ochratoxin A
CHEMBL589366
CHEMBL592694
CHEMBL603156
CHEMBL600271
C025589
20 / 32 / 57 234 / 18
C00037570 External link 512 Ochratoxin B
C045354

Human Protein / Gene in interactions

20 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P04637 Cellular tumor antigen p53 Transcription Factor C00003008 7 / 37
P04062 Glucosylceramidase Enzyme C00003008 6 / 4
P10253 Lysosomal alpha-glucosidase Hydrolase C00003008 1 / 1
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00003008 0 / 0
P10828 Thyroid hormone receptor beta NR1A2 C00003008 3 / 1
P11473 Vitamin D3 receptor NR1I1 C00003008 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00003008 0 / 0
Q8TCC7 Solute carrier family 22 member 8 Antiporter C00003008 0 / 0
Q4U2R8 Solute carrier family 22 member 6 Antiporter C00003008 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00003008 0 / 1
P37231 Peroxisome proliferator-activated receptor gamma NR1C3 C00003008 5 / 3
P06280 Alpha-galactosidase A Enzyme C00003008 1 / 1
Q96RI1 Bile acid receptor NR1H4 C00003008 0 / 0
Q92887 Canalicular multispecific organic anion transporter 1 Unclassified protein C00003008 1 / 1
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00003008 2 / 2
P03372 Estrogen receptor NR3A1 C00003008 1 / 1
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003008 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003008 0 / 0
P10275 Androgen receptor NR3C4 C00003008 3 / 4
Q9NSA0 Solute carrier family 22 member 11 Transporter C00003008 0 / 0

234 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
10351 ABCA8 ATP-binding cassette, sub-family A (ABC1), member 8 C00003008
10058 ABCB6, ABC, ABC14, DUH3, LAN, MCOPCB7, MTABC3, PRP, umat ATP-binding cassette, sub-family B (MDR/TAP), member 6 C00003008
1244 ABCC2, ABC30, CMOAT, DJS, MRP2, cMRP ATP-binding cassette, sub-family C (CFTR/MRP), member 2 C00003008
30 ACAA1, ACAA, PTHIO, THIO acetyl-CoA acyltransferase 1 (EC:2.3.1.16) C00003008
100380740 C00003008
196 AHR, bHLHe76 aryl hydrocarbon receptor C00003008
204 AK2, ADK2, AK_2 adenylate kinase 2 (EC:2.7.4.3) C00003008
1645 AKR1C1, 2-ALPHA-HSD, 20-ALPHA-HSD, C9, DD1, DD1/DD2, DDH, DDH1, H-37, HAKRC, HBAB, MBAB aldo-keto reductase family 1, member C1 (EC:1.3.1.20 1.1.1.149 1.1.1.112) C00003008
1646 AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) C00003008
8644 AKR1C3, DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, PGFS, hluPGFS aldo-keto reductase family 1, member C3 (EC:1.3.1.20 1.1.1.188 1.1.1.239 1.1.1.64 1.1.1.112 1.1.1.357) C00003008
213 ALB, PRO0883, PRO0903, PRO1341 albumin C00003008
79868 ALG13, CDG1S, CXorf45, GLT28D1, MDS031, TDRD13, YGL047W ALG13, UDP-N-acetylglucosaminyltransferase subunit (EC:3.4.19.12 2.4.1.141) C00003008
8639 AOC3, HPAO, SSAO, VAP-1, VAP1 amine oxidase, copper containing 3 (EC:1.4.3.21) C00003008
317 APAF1, APAF-1, CED4 apoptotic peptidase activating factor 1 C00003008
8542 APOL1, APO-L, APOL, APOL-I, FSGS4 apolipoprotein L, 1 C00003008
10565 ARFGEF1, ARFGEP1, BIG1, P200 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) C00003008
10123 ARL4C, ARL7, LAK ADP-ribosylation factor-like 4C C00003008
26225 ARL5A, ARFLP5, ARL5 ADP-ribosylation factor-like 5A C00003008
488 ATP2A2, ATP2B, DAR, DD, SERCA2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 (EC:3.6.3.8) C00003008
506 ATP5B, ATPMB, ATPSB ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide (EC:3.6.3.14) C00003008
513 ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit (EC:3.6.1.14) C00003008
522 ATP5J, ATP5, ATP5A, ATPM, CF6, F6 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F6 (EC:3.6.1.14) C00003008
10677 AVIL, ADVIL, DOC6, p92 advillin C00003008
10678 B3GNT2, B3GN-T2, B3GNT, B3GNT-2, B3GNT1, BETA3GNT, BGNT2, BGnT-2 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 2 (EC:2.4.1.149) C00003008
11285 B4GALT7, EDSP1, XGALT1, XGPT1 xylosylprotein beta 1,4-galactosyltransferase, polypeptide 7 (EC:2.4.1.133) C00003008
397543 C00003008
581 BAX, BCL2L4 BCL2-associated X protein C00003008
27113 BBC3, JFY-1, JFY1, PUMA BCL2 binding component 3 C00003008
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00003008
598 BCL2L1, BCL-XL/S, BCL2L, BCLX, BCLXL, BCLXS, Bcl-X, PPP1R52, bcl-xL, bcl-xS BCL2-like 1 C00003008
10904 BLCAP, BC10 bladder cancer associated protein C00003008
716061 C00003008
735 C9 complement component 9 C00003008
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00003008
840 CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) C00003008
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00003008
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00003008
847 CAT catalase (EC:1.11.1.6) C00003008
6358 CCL14, CC-1, CC-3, CKB1, HCC-1, HCC-1(1-74), HCC-1/HCC-3, HCC-3, MCIF, NCC-2, NCC2, SCYA14, SCYL2, SY14 chemokine (C-C motif) ligand 14 C00003008
891 CCNB1, CCNB cyclin B1 C00003008
900 CCNG1, CCNG cyclin G1 C00003008
100133941 CD24, CD24A CD24 molecule C00003008
10421 CD2BP2, FWP010, LIN1, PPP1R59, Snu40, U5-52K CD2 (cytoplasmic tail) binding protein 2 C00003008
995 CDC25C, CDC25, PPP1R60 cell division cycle 25C (EC:3.1.3.48) C00003008
983 CDK1, CDC2, CDC28A, P34CDC2 cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) C00003008
1026 CDKN1A, CAP20, CDKN1, CIP1, MDA-6, P21, SDI1, WAF1, p21CIP1 cyclin-dependent kinase inhibitor 1A (p21, Cip1) C00003008
1050 CEBPA, C/EBP-alpha, CEBP CCAAT/enhancer binding protein (C/EBP), alpha C00003008
1051 CEBPB, C/EBP-beta, CRP2, IL6DBP, LAP, LIP, NF-IL6, TCF5 CCAAT/enhancer binding protein (C/EBP), beta C00003008
1153 CIRBP, CIRP cold inducible RNA binding protein C00003008
51397 COMMD10, PTD002 COMM domain containing 10 C00003008
51122 COMMD2 COMM domain containing 2 C00003008
10229 COQ7, CAT5, CLK-1, CLK1 coenzyme Q7 homolog, ubiquinone (yeast) C00003008
1329 COX5B, COXVB cytochrome c oxidase subunit Vb (EC:1.9.3.1) C00003008
9167 COX7A2L, COX7AR, COX7RP, EB1, SIG81 cytochrome c oxidase subunit VIIa polypeptide 2 like C00003008
1351 COX8A, COX, COX8, COX8-2, COX8L, VIII, VIII-L cytochrome c oxidase subunit VIIIA (ubiquitous) (EC:1.9.3.1) C00003008
57325 CSRP2BP, ATAC2, CRP2BP, KAT14, PRO1194, dJ717M23.1 CSRP2 binding protein C00003008
1495 CTNNA1, CAP102 catenin (cadherin-associated protein), alpha 1, 102kDa C00003008
9820 CUL7, KIAA0076, dJ20C7.5 cullin 7 C00003008
1727 CYB5R3, B5R, DIA1 cytochrome b5 reductase 3 (EC:1.6.2.2) C00003008
1535 CYBA, p22-PHOX cytochrome b-245, alpha polypeptide C00003008
54205 CYCS, CYC, HCS, THC4 cytochrome c, somatic C00003008
1588 CYP19A1, ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM cytochrome P450, family 19, subfamily A, polypeptide 1 (EC:1.14.14.1) C00003008
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00003008
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00003008
1555 CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450 cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1) C00003008
1559 CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9 cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80) C00003008
1571 CYP2E1, CPE1, CYP2E, P450-J, P450C2E cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) C00003008
1576 CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1 cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157) C00003008
1577 CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3 cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1) C00003008
84259 DCUN1D5 DCN1, defective in cullin neddylation 1, domain containing 5 C00003008
1717 DHCR7, SLOS 7-dehydrocholesterol reductase (EC:1.3.1.21) C00003008
56616 DIABLO, DFNA64, SMAC diablo, IAP-binding mitochondrial protein C00003008
11083 DIDO1, BYE1, C20orf158, DATF-1, DATF1, DIDO2, DIDO3, DIO-1, DIO1, dJ885L7.8 death inducer-obliterator 1 C00003008
129563 DIS3L2, FAM6A, PRLMNS, hDIS3L2 DIS3 mitotic control homolog (S. cerevisiae)-like 2 C00003008
8847 DLEU2, 1B4, BCMSUN, DLB2, LEU2, LINC00022, MIR15AHG, NCRNA00022, RFP2OS, TRIM13OS deleted in lymphocytic leukemia 2 (non-protein coding) C00003008
1798 DPAGT1, ALG7, CDG-Ij, CDG1J, CMSTA2, D11S366, DGPT, DPAGT, DPAGT2, G1PT, GPT, UAGT, UGAT dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) (EC:2.7.8.15) C00003008
23333 DPY19L1 dpy-19-like 1 (C. elegans) C00003008
1632 ECI1, DCI enoyl-CoA delta isomerase 1 (EC:5.3.3.8) C00003008
30844 EHD4, PAST4 EH-domain containing 4 C00003008
27436 EML4, C2orf2, ELP120, EMAP-4, EMAPL4, ROPP120 echinoderm microtubule associated protein like 4 C00003008
2029 ENSA, ARPP-19e endosulfine alpha C00003008
2034 EPAS1, ECYT4, HIF2A, HLF, MOP2, PASD2, bHLHe73 endothelial PAS domain protein 1 C00003008
2066 ERBB4, ALS19, HER4, p180erbB4 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4 (EC:2.7.10.1) C00003008
2152 F3, CD142, TF, TFA coagulation factor III (thromboplastin, tissue factor) C00003008
2153 F5, FVL, PCCF, RPRGL1, THPH2 coagulation factor V (proaccelerin, labile factor) C00003008
2167 FABP4, A-FABP, AFABP, ALBP, aP2 fatty acid binding protein 4, adipocyte C00003008
8772 FADD, MORT1 Fas (TNFRSF6)-associated via death domain C00003008
3992 FADS1, D5D, FADS6, FADSD5, LLCDL1, TU12 fatty acid desaturase 1 (EC:1.14.19.-) C00003008
81889 FAHD1, C16orf36, YISKL fumarylacetoacetate hydrolase domain containing 1 (EC:3.7.1.5) C00003008
151354 FAM84A, NSE1, PP11517 family with sequence similarity 84, member A C00003008
355 FAS, ALPS1A, APO-1, APT1, CD95, FAS1, FASTM, TNFRSF6 Fas cell surface death receptor C00003008
8817 FGF18, FGF-18, ZFGF5 fibroblast growth factor 18 C00003008
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00003008
2487 FRZB, FRE, FRITZ, FRP-3, FRZB-1, FRZB-PEN, FRZB1, FZRB, OS1, SFRP3, SRFP3, hFIZ frizzled-related protein C00003008
2528 FUT6, FCT3A, FT1A, Fuc-TVI, FucT-VI fucosyltransferase 6 (alpha (1,3) fucosyltransferase) (EC:2.4.1.65) C00003008
35646 C00003008
2697 GJA1, AVSD3, CMDR, CX43, DFNB38, GJAL, HLHS1, HSS, ODDD gap junction protein, alpha 1, 43kDa C00003008
2814 GP5, CD42d, GPV glycoprotein V (platelet) C00003008
2876 GPX1, GPXD, GSHPX1 glutathione peroxidase 1 (EC:1.11.1.9) C00003008
2878 GPX3, GPx-P, GSHPx-3, GSHPx-P glutathione peroxidase 3 (plasma) (EC:1.11.1.9) C00003008
9446 GSTO1, GSTO_1-1, GSTTLp28, P28, SPG-R glutathione S-transferase omega 1 (EC:2.5.1.18 1.8.5.1 1.20.4.2) C00003008
404672 GTF2H5, C6orf175, TFB5, TFIIH, TGF2H5, TTD, TTD-A, TTDA, bA120J8.2 general transcription factor IIH, polypeptide 5 C00003008
3014 H2AFX, H2A.X, H2A/X, H2AX H2A histone family, member X C00003008
10767 HBS1L, EF-1a, ERFS, HBS1, HSPC276 HBS1-like (S. cerevisiae) C00003008
3010 HIST1H1T, H1FT, H1t, dJ221C16.2 histone cluster 1, H1t C00003008
3148 HMGB2, HMG2 high mobility group box 2 C00003008
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00003008
3303 HSPA1A, HSP70-1, HSP70-1A, HSP70I, HSP72, HSPA1 heat shock 70kDa protein 1A C00003008
3309 HSPA5, BIP, GRP78, MIF2 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) C00003008
3313 HSPA9, CSA, GRP-75, GRP75, HSPA9B, MOT, MOT2, MTHSP75, PBP74 heat shock 70kDa protein 9 (mortalin) C00003008
3315 HSPB1, CMT2F, HMN2B, HS.76067, HSP27, HSP28, Hsp25, SRP27 heat shock 27kDa protein 1 C00003008
3420 IDH3B, H-IDHB, RP46 isocitrate dehydrogenase 3 (NAD+) beta (EC:1.1.1.41) C00003008
3421 IDH3G, H-IDHG isocitrate dehydrogenase 3 (NAD+) gamma (EC:1.1.1.41) C00003008
3481 IGF2, C11orf43, IGF-II, PP9974 insulin-like growth factor 2 (somatomedin A) C00003008
3484 IGFBP1, AFBP, IBP1, IGF-BP25, PP12, hIGFBP-1 insulin-like growth factor binding protein 1 C00003008
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00003008
7850 IL1R2, CD121b, CDw121b, IL-1R-2, IL-1RT-2, IL-1RT2, IL1R2c, IL1RB interleukin 1 receptor, type II C00003008
3576 IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 interleukin 8 C00003008
23210 JMJD6, PSR, PTDSR, PTDSR1 jumonji domain containing 6 (EC:1.14.11.-) C00003008
3725 JUN, AP-1, AP1, c-Jun jun proto-oncogene C00003008
3726 JUNB, AP-1 jun B proto-oncogene C00003008
23189 KANK1, ANKRD15, CPSQ2, KANK KN motif and ankyrin repeat domains 1 C00003008
3758 KCNJ1, KIR1.1, ROMK, ROMK1 potassium inwardly-rectifying channel, subfamily J, member 1 C00003008
3772 KCNJ15, IRKK, KIR1.3, KIR4.2 potassium inwardly-rectifying channel, subfamily J, member 15 C00003008
23588 KLHDC2, HCLP-1, HCLP1, LCP kelch domain containing 2 C00003008
3866 KRT15, CK15, K15, K1CO keratin 15 C00003008
4023 LPL, HDLCQ11, LIPD lipoprotein lipase (EC:3.1.1.34) C00003008
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00003008
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00003008
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00003008
22919 MAPRE1, EB1 microtubule-associated protein, RP/EB family, member 1 C00003008
4155 MBP myelin basic protein C00003008
9412 MED21, SRB7, SURB7, hSrb7 mediator complex subunit 21 C00003008
9526 MPDU1, CDGIF, HBEBP2BPA, Lec35, My008, PP3958, PQLC5, SL15 mannose-P-dolichol utilization defect 1 C00003008
23164 MPRIP, M-RIP, MRIP, RHOIP3, RIP3, p116Rip myosin phosphatase Rho interacting protein C00003008
4489 MT1A, MT1, MT1S, MTC metallothionein 1A C00003008
4490 MT1B, MT1, MT1Q, MTP metallothionein 1B C00003008
4502 MT2A, MT2 metallothionein 2A C00003008
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00003008
79829 NAA40, NAT11, PATT1 N(alpha)-acetyltransferase 40, NatD catalytic subunit (EC:2.3.1.-) C00003008
4668 NAGA, D22S674, GALB N-acetylgalactosaminidase, alpha- (EC:3.2.1.49) C00003008
55577 NAGK, GNK, HSA242910 N-acetylglucosamine kinase (EC:2.7.1.59) C00003008
4694 NDUFA1, CI-MWFE, MWFE, ZNF183 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 1, 7.5kDa (EC:1.6.99.3) C00003008
4705 NDUFA10, CI-42KD, CI-42k NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 10, 42kDa (EC:1.6.5.3 1.6.99.3) C00003008
4696 NDUFA3, B9, CI-B9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 3, 9kDa C00003008
4701 NDUFA7, B14.5a NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa C00003008
4708 NDUFB2, AGGG, CI-AGGG NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa (EC:1.6.5.3 1.6.99.3) C00003008
4713 NDUFB7, B18, CI-B18 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 7, 18kDa (EC:1.6.5.3 1.6.99.3) C00003008
4717 NDUFC1, KFYI NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa C00003008
4726 NDUFS6, CI-13kA, CI-13kD-A, CI13KDA NADH dehydrogenase (ubiquinone) Fe-S protein 6, 13kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3) C00003008
374291 NDUFS7, CI-20, CI-20KD, MY017, PSST NADH dehydrogenase (ubiquinone) Fe-S protein 7, 20kDa (NADH-coenzyme Q reductase) (EC:1.6.5.3 1.6.99.3) C00003008
1728 NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) C00003008
3084 NRG1, ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, NDF, SMDF neuregulin 1 C00003008
29095 ORMDL2, MST095, MSTP095, adoplin-2 ORM1-like 2 (S. cerevisiae) C00003008
10914 PAPOLA, PAP poly(A) polymerase alpha (EC:2.7.7.19) C00003008
5106 PCK2, PEPCK, PEPCK-M, PEPCK2 phosphoenolpyruvate carboxykinase 2 (mitochondrial) (EC:4.1.1.32) C00003008
5111 PCNA proliferating cell nuclear antigen C00003008
5165 PDK3, CMTX6 pyruvate dehydrogenase kinase, isozyme 3 (EC:2.7.11.2) C00003008
55825 PECR, DCRRP, HPDHASE, HSA250303, PVIARL, SDR29C1, TERP peroxisomal trans-2-enoyl-CoA reductase (EC:1.3.1.38) C00003008
5211 PFKL, PFK-B phosphofructokinase, liver (EC:2.7.1.11) C00003008
5230 PGK1, MIG10, PGKA phosphoglycerate kinase 1 (EC:2.7.2.3) C00003008
55650 PIGV, GPI-MT-II, HPMRS1, PIG-V phosphatidylinositol glycan anchor biosynthesis, class V C00003008
80235 PIGZ, GPI-MT-IV, PIG-Z, SMP3 phosphatidylinositol glycan anchor biosynthesis, class Z C00003008
5329 PLAUR, CD87, U-PAR, UPAR, URKR plasminogen activator, urokinase receptor C00003008
5468 PPARG, CIMT1, GLM1, NR1C3, PPARG1, PPARG2, PPARgamma peroxisome proliferator-activated receptor gamma C00003008
5519 PPP2R1B, PP2A-Abeta, PR65B protein phosphatase 2, regulatory subunit A, beta (EC:3.1.3.16) C00003008
5532 PPP3CB, CALNA2, CALNB, CNA2, PP2Bbeta protein phosphatase 3, catalytic subunit, beta isozyme (EC:3.1.3.16) C00003008
10113 PREB, SEC12 prolactin regulatory element binding C00003008
5553 PRG2, BMPG, MBP, MBP1 proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) C00003008
5629 PROX1 prospero homeobox 1 C00003008
8899 PRPF4B, PR4H, PRP4, PRP4H, PRP4K, dJ1013A10.1 pre-mRNA processing factor 4B (EC:2.7.11.1) C00003008
5728 PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1 phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48) C00003008
5912 RAP2B RAP2B, member of RAS oncogene family C00003008
10125 RASGRP1, CALDAG-GEFI, CALDAG-GEFII, RASGRP, V, hRasGRP1 RAS guanyl releasing protein 1 (calcium and DAG-regulated) C00003008
5928 RBBP4, NURF55, RBAP48 retinoblastoma binding protein 4 C00003008
5984 RFC4, A1, RFC37 replication factor C (activator 1) 4, 37kDa C00003008
388 RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 ras homolog family member B C00003008
6117 RPA1, HSSB, MST075, REPA1, RF-A, RP-A, RPA70 replication protein A1, 70kDa C00003008
6137 RPL13, BBC1, D16S444E, D16S44E, L13 ribosomal protein L13 (EC:3.6.5.3) C00003008
10556 RPP30, TSG15 ribonuclease P/MRP 30kDa subunit (EC:3.1.26.5) C00003008
6209 RPS15, RIG, S15 ribosomal protein S15 C00003008
80230 RUFY1, RABIP4, ZFYVE12 RUN and FYVE domain containing 1 C00003008
6305 SBF1, CMT4B3, DENND7A, MTMR5 SET binding factor 1 C00003008
6309 SC5D, ERG3, S5DES, SC5DL sterol-C5-desaturase (EC:1.14.21.6) C00003008
22828 SCAF8, RBM16 SR-related CTD-associated factor 8 C00003008
6319 SCD, FADS5, MSTP008, SCD1, SCDOS stearoyl-CoA desaturase (delta-9-desaturase) (EC:1.14.19.1) C00003008
5055 SERPINB2, HsT1201, PAI, PAI-2, PAI2, PLANH2 serpin peptidase inhibitor, clade B (ovalbumin), member 2 C00003008
6464 SHC1, SHC, SHCA SHC (Src homology 2 domain containing) transforming protein 1 C00003008
4891 SLC11A2, DCT1, DMT1, NRAMP2 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 2 C00003008
55867 SLC22A11, OAT4, hOAT4 solute carrier family 22 (organic anion/urate transporter), member 11 C00003008
9356 SLC22A6, HOAT1, OAT1, PAHT, ROAT1 solute carrier family 22 (organic anion transporter), member 6 C00003008
9376 SLC22A8, OAT3 solute carrier family 22 (organic anion transporter), member 8 C00003008
7779 SLC30A1, ZNT1, ZRC1 solute carrier family 30 (zinc transporter), member 1 C00003008
64924 SLC30A5, ZNT5, ZNTL1, ZTL1, ZnT-5 solute carrier family 30 (zinc transporter), member 5 C00003008
55676 SLC30A6, MST103, MSTP103, ZNT6 solute carrier family 30 (zinc transporter), member 6 C00003008
148867 SLC30A7, ZNT7, ZnT-7, ZnTL2 solute carrier family 30 (zinc transporter), member 7 C00003008
27173 SLC39A1, ZIP1, ZIRTL solute carrier family 39 (zinc transporter), member 1 C00003008
57181 SLC39A10, LZT-Hs2 solute carrier family 39 (zinc transporter), member 10 C00003008
23516 SLC39A14, LZT-Hs4, NET34, ZIP14, cig19 solute carrier family 39 (zinc transporter), member 14 C00003008
7922 SLC39A7, D6S115E, D6S2244E, H2-KE4, HKE4, KE4, RING5, ZIP7 solute carrier family 39 (zinc transporter), member 7 C00003008
55334 SLC39A9, ZIP-9, ZIP9 solute carrier family 39, member 9 C00003008
6648 SOD2, IPOB, MNSOD, MVCD6 superoxide dismutase 2, mitochondrial (EC:1.15.1.1) C00003008
6649 SOD3, EC-SOD superoxide dismutase 3, extracellular (EC:1.15.1.1) C00003008
6652 SORD, SORD1 sorbitol dehydrogenase (EC:1.1.1.14) C00003008
6655 SOS2 son of sevenless homolog 2 (Drosophila) C00003008
55812 SPATA7, HSD-3.1, HSD3, LCA3 spermatogenesis associated 7 C00003008
26010 SPATS2L, DNAPTP6, SGNP spermatogenesis associated, serine-rich 2-like C00003008
6711 SPTBN1, ELF, SPTB2, betaSpII spectrin, beta, non-erythrocytic 1 C00003008
10254 STAM2, Hbp, STAM2A, STAM2B signal transducing adaptor molecule (SH3 domain and ITAM motif) 2 C00003008
6781 STC1, STC stanniocalcin 1 C00003008
8417 STX7 syntaxin 7 C00003008
23435 TARDBP, ALS10, TDP-43 TAR DNA binding protein C00003008
140738 TMEM37, PR, PR1 transmembrane protein 37 C00003008
757 TMEM50B, C21orf4, HCVP7TP3 transmembrane protein 50B C00003008
7124 TNF, DIF, TNF-alpha, TNFA, TNFSF2 tumor necrosis factor C00003008
7132 TNFRSF1A, CD120a, FPF, MS5, TBP1, TNF-R, TNF-R-I, TNF-R55, TNFAR, TNFR1, TNFR1-d2, TNFR55, TNFR60, p55, p55-R, p60 tumor necrosis factor receptor superfamily, member 1A C00003008
7157 TP53, BCC7, LFS1, P53, TRP53 tumor protein p53 C00003008
7170 TPM3, CAPM1, CFTD, NEM1, OK/SW-cl.5, TM-5, TM3, TM30, TM30nm, TM5, TPMsk3, TRK, hscp30 tropomyosin 3 C00003008
22906 TRAK1, MILT1, OIP106 trafficking protein, kinesin binding 1 C00003008
8805 TRIM24, PTC6, RNF82, TF1A, TIF1, TIF1A, TIF1ALPHA, hTIF1 tripartite motif containing 24 C00003008
8295 TRRAP, PAF350/400, PAF400, STAF40, TR-AP, Tra1 transformation/transcription domain-associated protein C00003008
81027 TUBB1 tubulin, beta 1 class VI C00003008
25828 TXN2, MT-TRX, MTRX, TRX2 thioredoxin 2 C00003008
7351 UCP2, BMIQ4, SLC25A8, UCPH uncoupling protein 2 (mitochondrial, proton carrier) C00003008
7352 UCP3, SLC25A9 uncoupling protein 3 (mitochondrial, proton carrier) C00003008
54578 UGT1A6, GNT1, HLUGP, HLUGP1, UDPGT, UDPGT_1-6, UGT1, UGT1A6S, UGT1F UDP glucuronosyltransferase 1 family, polypeptide A6 (EC:2.4.1.17) C00003008
65109 UPF3B, HUPF3B, MRXS14, RENT3B, UPF3X UPF3 regulator of nonsense transcripts homolog B (yeast) C00003008
708396 C00003008
7388 UQCRH, QCR6, UQCR8 ubiquinol-cytochrome c reductase hinge protein (EC:1.10.2.2) C00003008
27089 UQCRQ, MC3DN4, QCR8, QP-C, QPC, UQCR7 ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa (EC:1.10.2.2) C00003008
7422 VEGFA, MVCD1, VEGF, VPF vascular endothelial growth factor A C00003008
55339 WDR33, NET14, WDC146 WD repeat domain 33 C00003008
7498 XDH, XO, XOR xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) C00003008
22834 ZNF652 zinc finger protein 652 C00003008

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (32)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
%606641 Body mass index; bmi P37231
#609338 Carotid intimal medial thickness 1 P37231
#119900 Digital clubbing, isolated congenital P15428
#237500 Dubin-johnson syndrome; djs Q92887
#133239 Esophageal cancer P04637
#615363 Estrogen resistance; estrr P03372
#301500 Fabry disease P06280
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137800 Glioma susceptibility 1; glm1 P37231
#232300 Glycogen storage disease ii P10253
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#604367 Lipodystrophy, familial partial, type 3; fpld3 P37231
#211980 Lung cancer P04637
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#601665 Obesity P37231
#260500 Papilloma of choroid plexus; cpp P04637
#168600 Parkinson disease, late-onset; pd P04062
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (57)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
P04637 (related)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
P37231 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00125 Fabry disease P06280 (related)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00409 Type II diabetes mellitus P37231 (related)
H00420 Familial partial lipodystrophy (FPL) P37231 (related)
H00208 Hyperbilirubinemia Q92887 (related)

Diseases related to CTD interactions

18 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000236 Adenoma C00003008
D001943 Breast Neoplasms C00003008
D002277 Carcinoma C00003008
D019465 Craniofacial Abnormalities C00003008
D005355 Fibrosis C00003008
D042822 Genomic Instability C00003008
D007674 Kidney Diseases C00003008
D007680 Kidney Neoplasms C00003008
D008103 Liver Cirrhosis C00003008
D008113 Liver Neoplasms C00003008
D008325 Mammary Neoplasms, Experimental C00003008
D008850 Microphthalmos C00003008
D009436 Neural Tube Defects C00003008
D011041 Poisoning C00003008
D011201 Poultry Diseases C00003008
D011230 Precancerous Conditions C00003008
D013736 Testicular Neoplasms C00003008
D014571 Urologic Neoplasms C00003008