Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00027627 External link 512 (+)-Curacin A
CHEMBL55367
CHEMBL56708
CHEMBL58871
CHEMBL294667
CHEMBL57092
CHEMBL89138
CHEMBL508496
CHEMBL454328
CHEMBL2115069
C095843
15 / 7 / 2
C00028110 External link 512 Curacin D
CHEMBL56309
CHEMBL1714537
C116945
27 / 26 / 45

Human Protein / Gene in interactions

27 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9BVA1 Tubulin beta-2B chain Structural C00027627 C00028110 1 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00027627 C00028110 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00027627 C00028110 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00027627 C00028110 0 / 0
Q13885 Tubulin beta-2A chain Structural C00027627 C00028110 0 / 0
P68363 Tubulin alpha-1B chain Unclassified protein C00027627 C00028110 0 / 0
Q13509 Tubulin beta-3 chain Structural C00027627 C00028110 2 / 1
P68371 Tubulin beta-4B chain Structural C00027627 C00028110 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00027627 C00028110 1 / 1
P07437 Tubulin beta chain Structural C00027627 C00028110 0 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00027627 C00028110 0 / 0
P04350 Tubulin beta-4A chain Structural C00027627 C00028110 2 / 0
Q13748 Tubulin alpha-3C/D chain Structural C00027627 C00028110 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00027627 C00028110 1 / 0
P68366 Tubulin alpha-4A chain Structural C00027627 C00028110 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00028110 1 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00028110 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00028110 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00028110 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00028110 0 / 0
O75496 Geminin Unclassified protein C00028110 0 / 0
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00028110 2 / 0
P11473 Vitamin D3 receptor NR1I1 C00028110 2 / 3
P37840 Alpha-synuclein Unclassified protein C00028110 4 / 2
P49798 Regulator of G-protein signaling 4 Unclassified protein C00028110 2 / 0
Q99700 Ataxin-2 Unclassified protein C00028110 1 / 1
P04637 Cellular tumor antigen p53 Transcription Factor C00028110 7 / 37

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (26)

OMIM preferred title UniProt
#202300 Adrenocortical carcinoma, hereditary; adcc P04637
#614740 Basal cell carcinoma, susceptibility to, 7; bcc7 P04637
#114500 Colorectal cancer; crc P84022
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#127750 Dementia, lewy body; dlb P37840
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#133239 Esophageal cancer P04637
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#137800 Glioma susceptibility 1; glm1 O75874
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#151623 Li-fraumeni syndrome 1; lfs1 P04637
#611603 Lissencephaly 3; lis3 Q71U36
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#211980 Lung cancer P04637
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260500 Papilloma of choroid plexus; cpp P04637
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#275355 Squamous cell carcinoma, head and neck; hnscc P04637
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (45)

KEGG name UniProt
H00004 Chronic myeloid leukemia (CML) P04637 (related)
H00005 Chronic lymphocytic leukemia (CLL) P04637 (related)
H00006 Hairy-cell leukemia P04637 (related)
H00008 Burkitt lymphoma P04637 (related)
H00009 Adult T-cell leukemia P04637 (related)
H00010 Multiple myeloma P04637 (related)
H00013 Small cell lung cancer P04637 (related)
H00014 Non-small cell lung cancer P04637 (related)
H00015 Malignant pleural mesothelioma P04637 (related)
H00016 Oral cancer P04637 (related)
P04637 (marker)
H00017 Esophageal cancer P04637 (related)
P04637 (marker)
H00018 Gastric cancer P04637 (related)
H00019 Pancreatic cancer P04637 (related)
P04637 (marker)
H00020 Colorectal cancer P04637 (related)
P04637 (marker)
H00022 Bladder cancer P04637 (related)
H00025 Penile cancer P04637 (related)
P04637 (marker)
H00026 Endometrial Cancer P04637 (related)
H00027 Ovarian cancer P04637 (related)
H00028 Choriocarcinoma P04637 (related)
H00029 Vulvar cancer P04637 (related)
H00031 Breast cancer P04637 (related)
H00032 Thyroid cancer P04637 (related)
H00033 Adrenal carcinoma P04637 (related)
H00036 Osteosarcoma P04637 (related)
H00038 Malignant melanoma P04637 (related)
H00039 Basal cell carcinoma P04637 (related)
H00040 Squamous cell carcinoma P04637 (related)
H00041 Kaposi's sarcoma P04637 (related)
H00042 Glioma P04637 (related)
P04637 (marker)
H00044 Cancer of the anal canal P04637 (related)
H00046 Cholangiocarcinoma P04637 (related)
H00047 Gallbladder cancer P04637 (related)
H00048 Hepatocellular carcinoma P04637 (related)
H00055 Laryngeal cancer P04637 (related)
P04637 (marker)
H00881 Li-Fraumeni syndrome P04637 (related)
H01007 Choroid plexus papilloma P04637 (related)
H00021 Renal cell carcinoma P04637 (marker)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)