| class name | count | 
|---|
| class name | count | 
|---|
 
                  
                | br08003 Category | # of metabolite | 
|---|
| br08003 Category | KEGG ID | KNApSAcK ID | 
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link | # of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE | # of genes in CTD interaction / related diseases | figure | 
|---|---|---|---|---|---|---|
| C00027627   | (+)-Curacin A | CHEMBL55367 CHEMBL56708 CHEMBL58871 CHEMBL294667 CHEMBL57092 CHEMBL89138 CHEMBL508496 CHEMBL454328 CHEMBL2115069 | C095843 | 15 / 7 / 2 |   | |
| C00028110   | Curacin D | CHEMBL56309 CHEMBL1714537 | C116945 | 27 / 26 / 45 |   | 
| accession | description | class description | KNApSAcK metabolite in interactions | # of diseases (OMIM / KEGG) | 
|---|---|---|---|---|
| Q9BVA1 | Tubulin beta-2B chain | Structural | C00027627 C00028110 | 1 / 0 | 
| Q9BUF5 | Tubulin beta-6 chain | Structural | C00027627 C00028110 | 0 / 0 | 
| Q9BQE3 | Tubulin alpha-1C chain | Unclassified protein | C00027627 C00028110 | 0 / 0 | 
| Q6PEY2 | Tubulin alpha-3E chain | Unclassified protein | C00027627 C00028110 | 0 / 0 | 
| Q13885 | Tubulin beta-2A chain | Structural | C00027627 C00028110 | 0 / 0 | 
| P68363 | Tubulin alpha-1B chain | Unclassified protein | C00027627 C00028110 | 0 / 0 | 
| Q13509 | Tubulin beta-3 chain | Structural | C00027627 C00028110 | 2 / 1 | 
| P68371 | Tubulin beta-4B chain | Structural | C00027627 C00028110 | 0 / 0 | 
| Q71U36 | Tubulin alpha-1A chain | Structural | C00027627 C00028110 | 1 / 1 | 
| P07437 | Tubulin beta chain | Structural | C00027627 C00028110 | 0 / 0 | 
| Q3ZCM7 | Tubulin beta-8 chain | Structural | C00027627 C00028110 | 0 / 0 | 
| P04350 | Tubulin beta-4A chain | Structural | C00027627 C00028110 | 2 / 0 | 
| Q13748 | Tubulin alpha-3C/D chain | Structural | C00027627 C00028110 | 0 / 0 | 
| Q9H4B7 | Tubulin beta-1 chain | Structural | C00027627 C00028110 | 1 / 0 | 
| P68366 | Tubulin alpha-4A chain | Structural | C00027627 C00028110 | 0 / 0 | 
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00028110 | 1 / 0 | 
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00028110 | 0 / 0 | 
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00028110 | 0 / 0 | 
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00028110 | 0 / 0 | 
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00028110 | 0 / 0 | 
| O75496 | Geminin | Unclassified protein | C00028110 | 0 / 0 | 
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00028110 | 2 / 0 | 
| P11473 | Vitamin D3 receptor | NR1I1 | C00028110 | 2 / 3 | 
| P37840 | Alpha-synuclein | Unclassified protein | C00028110 | 4 / 2 | 
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00028110 | 2 / 0 | 
| Q99700 | Ataxin-2 | Unclassified protein | C00028110 | 1 / 1 | 
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00028110 | 7 / 37 | 
| OMIM | preferred title | UniProt | 
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc | P04637 | 
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 | P04637 | 
| #114500 | Colorectal cancer; crc | P84022 | 
| #614039 | Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 | Q13509 | 
| #127750 | Dementia, lewy body; dlb | P37840 | 
| #128101 | Dystonia 4, torsion, autosomal dominant; dyt4 | P04350 | 
| #133239 | Esophageal cancer | P04637 | 
| #600638 | Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a | Q13509 | 
| #137800 | Glioma susceptibility 1; glm1 | O75874 | 
| #612438 | Leukodystrophy, hypomyelinating, 6; hld6 | P04350 | 
| #151623 | Li-fraumeni syndrome 1; lfs1 | P04637 | 
| #611603 | Lissencephaly 3; lis3 | Q71U36 | 
| #613795 | Loeys-dietz syndrome, type 3; lds3 | P84022 | 
| #211980 | Lung cancer | P04637 | 
| #613112 | Macrothrombocytopenia, autosomal dominant, tubb1-related | Q9H4B7 | 
| #607948 | Mycobacterium tuberculosis, susceptibility to | P11473 | 
| #260500 | Papilloma of choroid plexus; cpp | P04637 | 
| #168601 | Parkinson disease 1, autosomal dominant; park1 | P37840 | 
| #605543 | Parkinson disease 4, autosomal dominant; park4 | P37840 | 
| #168600 | Parkinson disease, late-onset; pd | P37840 | 
| #610031 | Polymicrogyria, symmetric or asymmetric; pmgysa | Q9BVA1 | 
| #604906 | Schizophrenia 9; sczd9 | P49798 | 
| #181500 | Schizophrenia; sczd | P49798 | 
| #183090 | Spinocerebellar ataxia 2; sca2 | Q99700 | 
| #275355 | Squamous cell carcinoma, head and neck; hnscc | P04637 | 
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a | P11473 | 
| KEGG | name | UniProt | 
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) | P04637
                            (related) | 
| H00005 | Chronic lymphocytic leukemia (CLL) | P04637
                            (related) | 
| H00006 | Hairy-cell leukemia | P04637
                            (related) | 
| H00008 | Burkitt lymphoma | P04637
                            (related) | 
| H00009 | Adult T-cell leukemia | P04637
                            (related) | 
| H00010 | Multiple myeloma | P04637
                            (related) | 
| H00013 | Small cell lung cancer | P04637
                            (related) | 
| H00014 | Non-small cell lung cancer | P04637
                            (related) | 
| H00015 | Malignant pleural mesothelioma | P04637
                            (related) | 
| H00016 | Oral cancer | P04637
                            (related) P04637 (marker) | 
| H00017 | Esophageal cancer | P04637
                            (related) P04637 (marker) | 
| H00018 | Gastric cancer | P04637
                            (related) | 
| H00019 | Pancreatic cancer | P04637
                            (related) P04637 (marker) | 
| H00020 | Colorectal cancer | P04637
                            (related) P04637 (marker) | 
| H00022 | Bladder cancer | P04637
                            (related) | 
| H00025 | Penile cancer | P04637
                            (related) P04637 (marker) | 
| H00026 | Endometrial Cancer | P04637
                            (related) | 
| H00027 | Ovarian cancer | P04637
                            (related) | 
| H00028 | Choriocarcinoma | P04637
                            (related) | 
| H00029 | Vulvar cancer | P04637
                            (related) | 
| H00031 | Breast cancer | P04637
                            (related) | 
| H00032 | Thyroid cancer | P04637
                            (related) | 
| H00033 | Adrenal carcinoma | P04637
                            (related) | 
| H00036 | Osteosarcoma | P04637
                            (related) | 
| H00038 | Malignant melanoma | P04637
                            (related) | 
| H00039 | Basal cell carcinoma | P04637
                            (related) | 
| H00040 | Squamous cell carcinoma | P04637
                            (related) | 
| H00041 | Kaposi's sarcoma | P04637
                            (related) | 
| H00042 | Glioma | P04637
                            (related) P04637 (marker) | 
| H00044 | Cancer of the anal canal | P04637
                            (related) | 
| H00046 | Cholangiocarcinoma | P04637
                            (related) | 
| H00047 | Gallbladder cancer | P04637
                            (related) | 
| H00048 | Hepatocellular carcinoma | P04637
                            (related) | 
| H00055 | Laryngeal cancer | P04637
                            (related) P04637 (marker) | 
| H00881 | Li-Fraumeni syndrome | P04637
                            (related) | 
| H01007 | Choroid plexus papilloma | P04637
                            (related) | 
| H00021 | Renal cell carcinoma | P04637
                            (marker) | 
| H00342 | Tuberculosis | P11473
                            (related) | 
| H00784 | Localized autosomal recessive hypotrichosis | P11473
                            (related) | 
| H01143 | Vitamin D-dependent rickets | P11473
                            (related) | 
| H00057 | Parkinson's disease (PD) | P37840
                            (related) | 
| H00066 | Lewy body dementia (LBD) | P37840
                            (related) | 
| H00838 | Congenital fibrosis of the extraocular muscles (CFEOM) | Q13509
                            (related) | 
| H00268 | Lissencephaly (LIS) | Q71U36
                            (related) | 
| H00063 | Spinocerebellar ataxia (SCA) | Q99700
                            (related) |