KCF-S cluster No. 5526 (2 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (2)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Aspergillaceae	2

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (2)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00018753	MPA / Melbex / NSC 129185 / Lilly 68618 / Mycophenolic acid	CHEMBL866	D009173	111 / 72 / 58	29 / 11
C00039179	Euparvic acid / (-)-Euparvic acid	CHEMBL564205

Human Protein / Gene in interactions

111 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00018753	1 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00018753	4 / 1
Q9HAW8	UDP-glucuronosyltransferase 1-10	Enzyme	C00018753	0 / 0
P20839	Inosine-5'-monophosphate dehydrogenase 1	Oxidoreductase	C00018753	2 / 2
P21728	D(1A) dopamine receptor	Dopamine receptor	C00018753	0 / 0
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00018753	0 / 3
Q12809	Potassium voltage-gated channel subfamily H member 2	KCNH, Kv10-12.x (Ether-a-go-go)	C00018753	2 / 2
P08246	Neutrophil elastase	S1A	C00018753	2 / 1
P33765	Adenosine receptor A3	Adenosine receptor	C00018753	0 / 0
Q16539	Mitogen-activated protein kinase 14	p38	C00018753	0 / 0
P49146	Neuropeptide Y receptor type 2	Neuropeptide Y receptor	C00018753	0 / 0
P29466	Caspase-1	C14	C00018753	0 / 0
P17252	Protein kinase C alpha type	Alpha	C00018753	0 / 0
P27361	Mitogen-activated protein kinase 3	Erk	C00018753	0 / 0
P14780	Matrix metalloproteinase-9	M10A	C00018753	2 / 2
P02545	Prelamin-A/C	Unclassified protein	C00018753	11 / 10
P37840	Alpha-synuclein	Unclassified protein	C00018753	4 / 2
P12268	Inosine-5'-monophosphate dehydrogenase 2	Oxidoreductase	C00018753	0 / 0
P00918	Carbonic anhydrase 2	Lyase	C00018753	1 / 2
P07550	Beta-2 adrenergic receptor	Adrenergic receptor	C00018753	0 / 1
P21397	Amine oxidase [flavin-containing] A	Oxidoreductase	C00018753	1 / 1
P25021	Histamine H2 receptor	Histamine receptor	C00018753	0 / 0
P35367	Histamine H1 receptor	Histamine receptor	C00018753	0 / 0
Q01959	Sodium-dependent dopamine transporter	Dopamine	C00018753	1 / 0
P08912	Muscarinic acetylcholine receptor M5	Acetylcholine receptor	C00018753	0 / 0
P18825	Alpha-2C adrenergic receptor	Adrenergic receptor	C00018753	0 / 0
P13945	Beta-3 adrenergic receptor	Adrenergic receptor	C00018753	0 / 0
P25024	C-X-C chemokine receptor type 1	CXC chemokine receptor	C00018753	0 / 0
P06241	Tyrosine-protein kinase Fyn	Src	C00018753	0 / 0
Q08209	Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	Ser_Thr	C00018753	0 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00018753	0 / 1
Q9HAW7	UDP-glucuronosyltransferase 1-7	Enzyme	C00018753	0 / 0
P00533	Epidermal growth factor receptor	TK tyrosine-protein kinase EGFR subfamily	C00018753	1 / 8
P14416	D(2) dopamine receptor	Dopamine receptor	C00018753	2 / 0
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00018753	0 / 0
P37288	Vasopressin V1a receptor	Vasopressin and oxytocin receptor	C00018753	0 / 0
P41145	Kappa-type opioid receptor	Opioid receptor	C00018753	0 / 0
Q9Y271	Cysteinyl leukotriene receptor 1	Leukotriene receptor	C00018753	0 / 0
P29274	Adenosine receptor A2a	Adenosine receptor	C00018753	0 / 0
P25929	Neuropeptide Y receptor type 1	Neuropeptide Y receptor	C00018753	0 / 0
P50052	Type-2 angiotensin II receptor	Angiotensin receptor	C00018753	1 / 1
P17948	Vascular endothelial growth factor receptor 1	Vegfr	C00018753	0 / 0
P41968	Melanocortin receptor 3	Melanocortin receptor	C00018753	1 / 0
P00352	Retinal dehydrogenase 1	Enzyme	C00018753	0 / 0
P11509	Cytochrome P450 2A6	Cytochrome P450 2A6	C00018753	0 / 0
O75496	Geminin	Unclassified protein	C00018753	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00018753	0 / 0
P04035	3-hydroxy-3-methylglutaryl-coenzyme A reductase	Oxidoreductase	C00018753	0 / 0
P08913	Alpha-2A adrenergic receptor	Adrenergic receptor	C00018753	0 / 0
P21917	D(4) dopamine receptor	Dopamine receptor	C00018753	0 / 0
P30988	Calcitonin receptor	Calcitonin receptor	C00018753	0 / 0
P35462	D(3) dopamine receptor	Dopamine receptor	C00018753	1 / 0
P41143	Delta-type opioid receptor	Opioid receptor	C00018753	0 / 0
Q92731	Estrogen receptor beta	NR3A2	C00018753	0 / 1
P41595	5-hydroxytryptamine receptor 2B	Serotonin receptor	C00018753	0 / 0
P25101	Endothelin-1 receptor	Endothelin receptor	C00018753	0 / 0
P30411	B2 bradykinin receptor	Bradykinin receptor	C00018753	0 / 0
P32245	Melanocortin receptor 4	Melanocortin receptor	C00018753	1 / 0
P32238	Cholecystokinin receptor type A	Cholecystokinin receptor	C00018753	0 / 0
P08311	Cathepsin G	S1A	C00018753	0 / 0
Q99720	Sigma non-opioid intracellular receptor 1	Membrane receptor	C00018753	1 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00018753	0 / 0
P03956	Interstitial collagenase	M10A	C00018753	0 / 1
P32241	Vasoactive intestinal polypeptide receptor 1	Vasoactive intestinal peptide receptor	C00018753	0 / 0
P04150	Glucocorticoid receptor	NR3C1	C00018753	0 / 1
P08172	Muscarinic acetylcholine receptor M2	Acetylcholine receptor	C00018753	2 / 0
P11229	Muscarinic acetylcholine receptor M1	Acetylcholine receptor	C00018753	0 / 0
P21554	Cannabinoid receptor 1	Cannabinoid receptor	C00018753	0 / 0
P31645	Sodium-dependent serotonin transporter	Serotonin	C00018753	2 / 0
P37231	Peroxisome proliferator-activated receptor gamma	NR1C3	C00018753	5 / 3
P04626	Receptor tyrosine-protein kinase erbB-2	TK tyrosine-protein kinase EGFR subfamily	C00018753	5 / 9
P20309	Muscarinic acetylcholine receptor M3	Acetylcholine receptor	C00018753	1 / 0
P21452	Substance-K receptor	Neurokinin receptor	C00018753	0 / 0
P51679	C-C chemokine receptor type 4	CC chemokine receptor	C00018753	0 / 0
P51681	C-C chemokine receptor type 5	CC chemokine receptor	C00018753	3 / 0
P50406	5-hydroxytryptamine receptor 6	Serotonin receptor	C00018753	0 / 0
P41597	C-C chemokine receptor type 2	CC chemokine receptor	C00018753	1 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00018753	0 / 0
P08575	Receptor-type tyrosine-protein phosphatase C	Enzyme	C00018753	2 / 1
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00018753	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00018753	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00018753	2 / 2
Q9HAW9	UDP-glucuronosyltransferase 1-8	Enzyme	C00018753	0 / 0
O76074	cGMP-specific 3',5'-cyclic phosphodiesterase	PDE_5A	C00018753	0 / 0
P03372	Estrogen receptor	NR3A1	C00018753	1 / 1
P08588	Beta-1 adrenergic receptor	Adrenergic receptor	C00018753	1 / 0
P22303	Acetylcholinesterase	Hydrolase	C00018753	1 / 0
P28223	5-hydroxytryptamine receptor 2A	Serotonin receptor	C00018753	0 / 0
P28335	5-hydroxytryptamine receptor 2C	Serotonin receptor	C00018753	0 / 0
P35372	Mu-type opioid receptor	Opioid receptor	C00018753	0 / 0
P08173	Muscarinic acetylcholine receptor M4	Acetylcholine receptor	C00018753	0 / 0
P25103	Substance-P receptor	Neurokinin receptor	C00018753	0 / 0
P25105	Platelet-activating factor receptor	PAF receptor	C00018753	0 / 0
P33032	Melanocortin receptor 5	Melanocortin receptor	C00018753	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00018753	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00018753	0 / 1
P05181	Cytochrome P450 2E1	Cytochrome P450 2E1	C00018753	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00018753	5 / 1
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00018753	0 / 0
P23975	Sodium-dependent noradrenaline transporter	Norepinephrine	C00018753	1 / 1
P25100	Alpha-1D adrenergic receptor	Adrenergic receptor	C00018753	0 / 0
P30542	Adenosine receptor A1	Adenosine receptor	C00018753	0 / 0
P18089	Alpha-2B adrenergic receptor	Adrenergic receptor	C00018753	0 / 0
P24557	Thromboxane-A synthase	Cytochrome P450 5A1	C00018753	1 / 1
P06239	Tyrosine-protein kinase Lck	Src	C00018753	0 / 1
P25025	C-X-C chemokine receptor type 2	CXC chemokine receptor	C00018753	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00018753	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00018753	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00018753	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00018753	1 / 4
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00018753	1 / 1

29 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00018753
466	ATF1, EWS-ATF1, FUS/ATF-1, TREB36	activating transcription factor 1	C00018753
581	BAX, BCL2L4	BCL2-associated X protein	C00018753
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00018753
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00018753
1027	CDKN1B, CDKN4, KIP1, MEN1B, MEN4, P27KIP1	cyclin-dependent kinase inhibitor 1B (p27, Kip1)	C00018753
1385	CREB1, CREB	cAMP responsive element binding protein 1	C00018753
1558	CYP2C8, CPC8, CYPIIC8, MP-12/MP-20	cytochrome P450, family 2, subfamily C, polypeptide 8 (EC:1.14.14.1)	C00018753
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00018753
1577	CYP3A5, CP35, CYPIIIA5, P450PCN3, PCN3	cytochrome P450, family 3, subfamily A, polypeptide 5 (EC:1.14.14.1)	C00018753
2353	FOS, AP-1, C-FOS, p55	FBJ murine osteosarcoma viral oncogene homolog	C00018753
2932	GSK3B	glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26)	C00018753
3558	IL2, IL-2, TCGF, lymphokine	interleukin 2	C00018753
3576	IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1	interleukin 8	C00018753
22914	KLRK1, CD314, D12S2489E, KLR, NKG2-D, NKG2D	killer cell lectin-like receptor subfamily K, member 1	C00018753
4067	LYN, JTK8, p53Lyn, p56Lyn	v-yes-1 Yamaguchi sarcoma viral related oncogene homolog (EC:2.7.10.2)	C00018753
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00018753
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00018753
5599	MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c	mitogen-activated protein kinase 8 (EC:2.7.11.24)	C00018753
5601	MAPK9, JNK-55, JNK2, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, SAPK, SAPK1a, p54a, p54aSAPK	mitogen-activated protein kinase 9 (EC:2.7.11.24)	C00018753
4137	MAPT, DDPAC, FTDP-17, MAPTL, MSTD, MTBT1, MTBT2, PPND, TAU	microtubule-associated protein tau	C00018753
9437	NCR1, CD335, LY94, NK-p46, NKP46	natural cytotoxicity triggering receptor 1	C00018753
9436	NCR2, CD336, LY95, NK-p44, NKP44, dJ149M18.1	natural cytotoxicity triggering receptor 2	C00018753
259197	NCR3, 1C7, CD337, LY117, MALS, NKp30	natural cytotoxicity triggering receptor 3	C00018753
5578	PRKCA, AAG6, PKC-alpha, PKCA, PRKACA	protein kinase C, alpha (EC:2.7.11.13)	C00018753
5970	RELA, NFKB3, p65	v-rel avian reticuloendotheliosis viral oncogene homolog A	C00018753
6194	RPS6, S6	ribosomal protein S6	C00018753
6776	STAT5A, MGF, STAT5	signal transducer and activator of transcription 5A	C00018753
54600	UGT1A9, HLUGP4, LUGP4, UDPGT, UDPGT_1-9, UGT-1I, UGT1-09, UGT1-9, UGT1.9, UGT1AI, UGT1I	UDP glucuronosyltransferase 1 family, polypeptide A9 (EC:2.4.1.17)	C00018753

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions