KCF-S cluster No. 5778 (1 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|
Cumulative family count
| class name | count |
|---|---|
| Pseudomonadaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00007533
|
2-Aminophenol
|
CHEMBL28319
|
C027667
|
22 / 17 / 10 | 6 / 2 |
|
Human Protein / Gene in interactions
22 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P22310 | UDP-glucuronosyltransferase 1-4 | Enzyme | C00007533 | 3 / 0 |
| Q9HAW8 | UDP-glucuronosyltransferase 1-10 | Enzyme | C00007533 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00007533 | 3 / 2 |
| P16662 | UDP-glucuronosyltransferase 2B7 | Enzyme | C00007533 | 0 / 0 |
| Q9HAW7 | UDP-glucuronosyltransferase 1-7 | Enzyme | C00007533 | 0 / 0 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00007533 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00007533 | 0 / 0 |
| P10145 | Interleukin-8 | Secreted protein | C00007533 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00007533 | 1 / 2 |
| P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00007533 | 5 / 3 |
| Q96RI1 | Bile acid receptor | NR1H4 | C00007533 | 0 / 0 |
| P51449 | Nuclear receptor ROR-gamma | Nuclear hormone receptor subfamily 1 group F member 3 | C00007533 | 0 / 0 |
| P06133 | UDP-glucuronosyltransferase 2B4 | Enzyme | C00007533 | 0 / 0 |
| P36537 | UDP-glucuronosyltransferase 2B10 | Enzyme | C00007533 | 0 / 0 |
| Q9BY64 | UDP-glucuronosyltransferase 2B28 | Enzyme | C00007533 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00007533 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00007533 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00007533 | 0 / 0 |
| P10275 | Androgen receptor | NR3C4 | C00007533 | 3 / 4 |
| P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00007533 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00007533 | 1 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00007533 | 0 / 0 |
6 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 1646 | AKR1C2, AKR1C-pseudo, BABP, DD, DD2, DDH2, HAKRD, HBAB, MCDR2, SRXY8 | aldo-keto reductase family 1, member C2 (EC:1.3.1.20 1.1.1.357) |
C00007533
|
| 1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00007533
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00007533
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00007533
|
| 1728 | NQO1, DHQU, DIA4, DTD, NMOR1, NMORI, QR1 | NAD(P)H dehydrogenase, quinone 1 (EC:1.6.5.2) |
C00007533
|
| 10720 | UGT2B11 | UDP glucuronosyltransferase 2 family, polypeptide B11 (EC:2.4.1.17) |
C00007533
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (17)
| OMIM | preferred title | UniProt |
|---|---|---|
| #300068 | Androgen insensitivity syndrome; ais |
P10275
|
| #312300 | Androgen insensitivity, partial; pais |
P10275
|
| %606641 | Body mass index; bmi |
P37231
|
| #609338 | Carotid intimal medial thickness 1 |
P37231
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #218800 | Crigler-najjar syndrome, type i |
P22310
|
| #606785 | Crigler-najjar syndrome, type ii |
P22310
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #143500 | Gilbert syndrome |
P22310
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
P37231 |
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #601665 | Obesity |
P37231
|
| #313200 | Spinal and bulbar muscular atrophy, x-linked 1; smax1 |
P10275
|
KEGG DISEASE (10)
| KEGG | name | UniProt |
|---|---|---|
| H00024 | Prostate cancer |
P10275
(related)
P11308 (related) |
| H00062 | Spinal and bulbar muscular atrophy (SBMA) |
P10275
(related)
|
| H00608 | 46,XY disorders of sex development (Disorders in androgen synthesis or action) |
P10275
(related)
|
| H00609 | 46,XY disorders of sex development (Other) |
P10275
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00032 | Thyroid cancer |
P37231
(related)
|
| H00409 | Type II diabetes mellitus |
P37231
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|