Plant Species


Cumulative plant class count

class name count
rosids 1

Cumulative family count

class name count
Brassicaceae 1
Enterobacteriaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00007381 External link 512 Quinolinic acid
CHEMBL286204
D017378
28 / 18 / 18 1 / 17

Human Protein / Gene in interactions

28 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00007381 1 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00007381 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00007381 2 / 0
P09917 Arachidonate 5-lipoxygenase Oxidoreductase C00007381 0 / 0
P22894 Neutrophil collagenase M10A C00007381 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00007381 2 / 2
P16473 Thyrotropin receptor Glycohormone receptor C00007381 3 / 2
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00007381 0 / 1
P54132 Bloom syndrome protein Enzyme C00007381 1 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00007381 0 / 0
P39748 Flap endonuclease 1 Enzyme C00007381 0 / 0
P03956 Interstitial collagenase M10A C00007381 0 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00007381 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00007381 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00007381 0 / 0
P08253 72 kDa type IV collagenase M10A C00007381 1 / 3
P16050 Arachidonate 15-lipoxygenase Enzyme C00007381 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00007381 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00007381 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00007381 0 / 0
Q6W5P4 Neuropeptide S receptor Neuropeptide receptor C00007381 1 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00007381 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00007381 4 / 3
P08254 Stromelysin-1 M10A C00007381 1 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00007381 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00007381 0 / 0
Q13951 Core-binding factor subunit beta Unclassified protein C00007381 0 / 1
Q01196 Runt-related transcription factor 1 Unclassified protein C00007381 1 / 4

1 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
2246 FGF1, AFGF, ECGF, ECGF-beta, ECGFA, ECGFB, FGF-1, FGF-alpha, FGFA, GLIO703, HBGF-1, HBGF1 fibroblast growth factor 1 (acidic) C00007381

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#608584 Asthma-related traits, susceptibility to, 2 Q6W5P4
#210900 Bloom syndrome; blm P54132
#614466 Coronary heart disease, susceptibility to, 6; chds6 P08254
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#600274 Frontotemporal dementia; ftd P10636
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#603932 Intervertebral disc disease; idd P14780
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#259600 Multicentric osteolysis, nodulosis, and arthropathy; mona P08253
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601399 Platelet disorder, familial, with associated myeloid malignancy Q01196
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (18)

KEGG name UniProt
H00028 Choriocarcinoma P03956 (related)
P08253 (related)
H00025 Penile cancer P08253 (related)
P14780 (related)
H00472 Torg-Winchester syndrome P08253 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q01196 (related)
Q01196 (marker)
H00003 Acute myeloid leukemia (AML) Q01196 (related)
Q01196 (marker)
Q13951 (marker)
H00004 Chronic myeloid leukemia (CML) Q01196 (related)
H00978 Thrombocytopenia (THC) Q01196 (related)

Diseases related to CTD interactions

17 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001321 Autistic Disorder C00007381
D001927 Brain Diseases C00007381
D001930 Brain Injuries C00007381
D002375 Catalepsy C00007381
D003072 Cognition Disorders C00007381
D004195 Disease Models, Animal C00007381
D004409 Dyskinesia, Drug-Induced C00007381
D004421 Dystonia C00007381
D020803 Encephalitis, Herpes Simplex C00007381
D006816 Huntington Disease C00007381
D008569 Memory Disorders C00007381
D009069 Movement Disorders C00007381
D009410 Nerve Degeneration C00007381
D009422 Nervous System Diseases C00007381
D020258 Neurotoxicity Syndromes C00007381
D012640 Seizures C00007381
D015431 Weight Loss C00007381