class name | count |
---|---|
Liliopsida | 2 |
class name | count |
---|---|
Amaryllidaceae | 2 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00001243
![]() |
Diallyl disulfide
|
CHEMBL366603
|
C028009
|
11 / 10 / 9 | 33 / 5 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P11473 | Vitamin D3 receptor | NR1I1 | C00001243 | 2 / 3 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00001243 | 0 / 0 |
O75762 | Transient receptor potential cation channel subfamily A member 1 | Unclassified protein | C00001243 | 1 / 0 |
P15428 | 15-hydroxyprostaglandin dehydrogenase [NAD(+)] | Enzyme | C00001243 | 2 / 2 |
P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001243 | 0 / 0 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001243 | 0 / 1 |
P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00001243 | 0 / 0 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00001243 | 0 / 0 |
P37088 | Amiloride-sensitive sodium channel subunit alpha | NA | C00001243 | 2 / 2 |
P51168 | Amiloride-sensitive sodium channel subunit beta | Unclassified protein | C00001243 | 3 / 3 |
P51170 | Amiloride-sensitive sodium channel subunit gamma | Unclassified protein | C00001243 | 2 / 3 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
5243 | ABCB1, ABC20, CD243, CLCS, GP170, MDR1, P-GP, PGY1 | ATP-binding cassette, sub-family B (MDR/TAP), member 1 (EC:3.6.3.44) |
C00001243
|
4363 | ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 |
C00001243
|
8714 | ABCC3, ABC31, EST90757, MLP2, MOAT-D, MRP3, cMOAT2 | ATP-binding cassette, sub-family C (CFTR/MRP), member 3 |
C00001243
|
10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00001243
|
368 | ABCC6, ABC34, ARA, EST349056, GACI2, MLP1, MOAT-E, MOATE, MRP6, PXE, PXE1, URG7 | ATP-binding cassette, sub-family C (CFTR/MRP), member 6 |
C00001243
|
467 | ATF3 | activating transcription factor 3 |
C00001243
|
596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001243
|
836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001243
|
842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001243
|
857 | CAV1, BSCL3, CGL3, MSTP085, PPH3, VIP21, CAV | caveolin 1, caveolae protein, 22kDa |
C00001243
|
891 | CCNB1, CCNB | cyclin B1 |
C00001243
|
999 | CDH1, Arc-1, CD324, CDHE, ECAD, LCAM, UVO | cadherin 1, type 1, E-cadherin (epithelial) |
C00001243
|
983 | CDK1, CDC2, CDC28A, P34CDC2 | cyclin-dependent kinase 1 (EC:2.7.11.23 2.7.11.22) |
C00001243
|
9075 | CLDN2 | claudin 2 |
C00001243
|
1365 | CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 | claudin 3 |
C00001243
|
1364 | CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R | claudin 4 |
C00001243
|
7122 | CLDN5, AWAL, BEC1, CPETRL1, TMVCF | claudin 5 |
C00001243
|
1499 | CTNNB1, CTNNB, MRD19, armadillo | catenin (cadherin-associated protein), beta 1, 88kDa |
C00001243
|
1543 | CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX | cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) |
C00001243
|
1548 | CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB | cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1) |
C00001243
|
24300 |
C00001243
|
||
361523 |
C00001243
|
||
1571 | CYP2E1, CPE1, CYP2E, P450-J, P450C2E | cytochrome P450, family 2, subfamily E, polypeptide 1 (EC:1.14.13.n7) |
C00001243
|
9518 | GDF15, GDF-15, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB | growth differentiation factor 15 |
C00001243
|
3725 | JUN, AP-1, AP1, c-Jun | jun proto-oncogene |
C00001243
|
5599 | MAPK8, JNK, JNK-46, JNK1, JNK1A2, JNK21B1/2, PRKM8, SAPK1, SAPK1c | mitogen-activated protein kinase 8 (EC:2.7.11.24) |
C00001243
|
4313 | MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 | matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) |
C00001243
|
4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00001243
|
4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00001243
|
6615 | SNAI1, SLUGH2, SNA, SNAH, SNAIL, SNAIL1, dJ710H13.1 | snail family zinc finger 1 |
C00001243
|
7076 | TIMP1, CLGI, EPA, EPO, HCI, TIMP | TIMP metallopeptidase inhibitor 1 |
C00001243
|
7077 | TIMP2, CSC-21K, DDC8 | TIMP metallopeptidase inhibitor 2 |
C00001243
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00001243
|
OMIM | preferred title | UniProt |
---|---|---|
#211400 | Bronchiectasis with or without elevated sweat chloride 1; besc1 |
P51168
|
#613021 | Bronchiectasis with or without elevated sweat chloride 2; besc2 |
P37088
|
#613071 | Bronchiectasis with or without elevated sweat chloride 3; besc3 |
P51170
|
#119900 | Digital clubbing, isolated congenital |
P15428
|
#615040 | Episodic pain syndrome, familial, 1; feps1 |
O75762
|
#259100 | Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 |
P15428
|
#177200 | Liddle syndrome |
P51168
P51170 |
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#264350 | Pseudohypoaldosteronism, type i, autosomal recessive; pha1b |
P37088
P51168 |
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG | name | UniProt |
---|---|---|
H00036 | Osteosarcoma |
P08684
(marker)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00457 | Primary hypertrophic osteoarthropathy (PHO) |
P15428
(related)
|
H01246 | Isolated congenital nail clubbing (ICNC) |
P15428
(related)
|
H00243 | Hyperkalemic distal renal tubular acidosis (RTA type 4) |
P37088
(related)
P51168 (related) P51170 (related) |
H00892 | Bronchiectasis with or without elevated sweat chloride |
P37088
(related)
P51168 (related) P51170 (related) |
H00242 | Liddle syndrome |
P51168
(related)
P51170 (related) |