KCF-S cluster No. 634 (13 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|
Cumulative family count
| class name | count |
|---|---|
| Streptomycetaceae | 11 |
| Pseudonocardiaceae | 2 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (13)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00017961
|
Bleomycin DMA2
/ Demethylbleomycin A2 |
|
||||
|
C00017962
|
Bleomycin A2'-a
|
|
||||
|
C00017963
|
Bleomycin A2'-c
|
|
||||
|
C00017964
|
Bleomycin B'1
/ Bleomycin B1' |
|
||||
|
C00017965
|
Bleomycin B6
|
|
||||
|
C00018152
|
NSC 279496
/ Talisomycin / Talisomycin A / Tallysomycin A / Antibiotic BU 2231A |
|
||||
|
C00018153
|
Talisomycin B
/ Tallysomycin B / Antibiotic BU 2231B |
|
||||
|
C00018300
|
Cleomycin B2
|
C027447
|
|
|||
|
C00018738
|
Bleogin
/ Bleomycin A2 / Pingyangmycin A2 / Zhengguangmycin A2 |
CHEMBL409164
CHEMBL403664 CHEMBL2010411 |
|
|||
|
C00018853
|
Bleomycin B2
/ Phleomycin D2 / Zhengguangmycin B2 / Dehydrophleomycin D1 |
CHEMBL1794651
|
|
|||
|
C00018854
|
Bleomycin A'2-b
/ Bleomycin A2'-b |
|
||||
|
C00027949
|
Bleomycin A5
/ Pingyangmycin A5 / Zhengguangmycin A5 |
CHEMBL2002141
CHEMBL2029115 |
C025703
|
88 / 1 |
|
|
|
C00040733
|
Zorbamycin
|
|
Human Protein / Gene in interactions
88 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 55347 | ABHD10 | abhydrolase domain containing 10 (EC:3.1.1.93) |
C00027949
|
| 79087 | ALG12, CDG1G, ECM39, PP14673, hALG12 | ALG12, alpha-1,6-mannosyltransferase (EC:2.4.1.260) |
C00027949
|
| 23600 | AMACR, AMACRD, CBAS4, RACE, RM | alpha-methylacyl-CoA racemase (EC:5.1.99.4) |
C00027949
|
| 378 | ARF4, ARF2 | ADP-ribosylation factor 4 |
C00027949
|
| 567 | B2M | beta-2-microglobulin |
C00027949
|
| 650 | BMP2, BDA2, BMP2A | bone morphogenetic protein 2 |
C00027949
|
| 768 | CA9, CAIX, MN | carbonic anhydrase IX (EC:4.2.1.1) |
C00027949
|
| 64921 | CASD1, C7orf12, NBLA04196 | CAS1 domain containing 1 |
C00027949
|
| 834 | CASP1, ICE, IL1BC, P45 | caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) |
C00027949
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00027949
|
| 53841 | CDHR5, MU-PCDH, MUCDHL, MUPCDH | cadherin-related family member 5 |
C00027949
|
| 1349 | COX7B, APLCC | cytochrome c oxidase subunit VIIb (EC:1.9.3.1) |
C00027949
|
| 8451 | CUL4A | cullin 4A |
C00027949
|
| 54541 | DDIT4, Dig2, REDD-1, REDD1 | DNA-damage-inducible transcript 4 |
C00027949
|
| 1718 | DHCR24, DCE, Nbla03646, SELADIN1, seladin-1 | 24-dehydrocholesterol reductase (EC:1.3.1.72) |
C00027949
|
| 22943 | DKK1, DKK-1, SK | dickkopf WNT signaling pathway inhibitor 1 |
C00027949
|
| 1808 | DPYSL2, CRMP-2, CRMP2, DHPRP2, DRP-2, DRP2, N2A3, ULIP-2, ULIP2 | dihydropyrimidinase-like 2 |
C00027949
|
| 30844 | EHD4, PAST4 | EH-domain containing 4 |
C00027949
|
| 1981 | EIF4G1, EIF-4G1, EIF4F, EIF4G, EIF4GI, P220, PARK18 | eukaryotic translation initiation factor 4 gamma, 1 |
C00027949
|
| 51234 | EMC4, PIG17, TMEM85 | ER membrane protein complex subunit 4 |
C00027949
|
| 56851 | EMC7, C11orf3, C15orf24, ORF1-FL1 | ER membrane protein complex subunit 7 |
C00027949
|
| 2026 | ENO2, NSE | enolase 2 (gamma, neuronal) (EC:4.2.1.11) |
C00027949
|
| 2201 | FBN2, CCA, DA9 | fibrillin 2 |
C00027949
|
| 2280 | FKBP1A, FKBP-12, FKBP-1A, FKBP1, FKBP12, PKC12, PKCI2, PPIASE | FK506 binding protein 1A, 12kDa (EC:5.2.1.8) |
C00027949
|
| 11328 | FKBP9, FKBP60, FKBP63, PPIase | FK506 binding protein 9, 63 kDa (EC:5.2.1.8) |
C00027949
|
| 10817 | FRS3, FRS2-beta, FRS2B, FRS2beta, SNT-2, SNT2 | fibroblast growth factor receptor substrate 3 |
C00027949
|
| 55568 | GALNT10, GALNACT10, PPGALNACT10, PPGANTASE10 | UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10 (GalNAc-T10) (EC:2.4.1.41) |
C00027949
|
| 2729 | GCLC, GCL, GCS, GLCL, GLCLC | glutamate-cysteine ligase, catalytic subunit (EC:6.3.2.2) |
C00027949
|
| 2791 | GNG11, GNGT11 | guanine nucleotide binding protein (G protein), gamma 11 |
C00027949
|
| 373156 | GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1 | glutathione S-transferase kappa 1 (EC:2.5.1.18) |
C00027949
|
| 85236 | HIST1H2BK, H2B/S, H2BFAiii, H2BFT, H2BK | histone cluster 1, H2bk |
C00027949
|
| 3107 | HLA-C, D6S204, HLA-JY3, HLC-C, PSORS1 | major histocompatibility complex, class I, C |
C00027949
|
| 3182 | HNRNPAB, ABBP1, HNRPAB | heterogeneous nuclear ribonucleoprotein A/B |
C00027949
|
| 3217 | HOXB7, HHO.C1, HOX2, HOX2C, Hox-2.3 | homeobox B7 |
C00027949
|
| 10808 | HSPH1, HSP105, HSP105A, HSP105B, NY-CO-25 | heat shock 105kDa/110kDa protein 1 |
C00027949
|
| 3419 | IDH3A | isocitrate dehydrogenase 3 (NAD+) alpha (EC:1.1.1.41) |
C00027949
|
| 3422 | IDI1, IPP1, IPPI1 | isopentenyl-diphosphate delta isomerase 1 (EC:5.3.3.2) |
C00027949
|
| 3678 | ITGA5, CD49e, FNRA, VLA5A | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) |
C00027949
|
| 3693 | ITGB5 | integrin, beta 5 |
C00027949
|
| 3708 | ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29 | inositol 1,4,5-trisphosphate receptor, type 1 |
C00027949
|
| 23522 | KAT6B, GTPTS, MORF, MOZ2, MYST4, ZC2HC6B, qkf, querkopf | K(lysine) acetyltransferase 6B (EC:2.3.1.48) |
C00027949
|
| 27076 | LYPD3, C4.4A | LY6/PLAUR domain containing 3 |
C00027949
|
| 4113 | MAGEB2, CT3.2, DAM6, MAGE-XP-2 | melanoma antigen family B, 2 |
C00027949
|
| 11253 | MAN1B1, ERMAN1, MANA-ER, MRT15 | mannosidase, alpha, class 1B, member 1 (EC:3.2.1.113) |
C00027949
|
| 4171 | MCM2, BM28, CCNL1, CDCL1, D3S3194, MITOTIN, cdc19 | minichromosome maintenance complex component 2 (EC:3.6.4.12) |
C00027949
|
| 400569 | MED11 | mediator complex subunit 11 |
C00027949
|
| 79006 | METRN, C16orf23, c380A1.2 | meteorin, glial cell differentiation regulator |
C00027949
|
| 4490 | MT1B, MT1, MT1Q, MTP | metallothionein 1B |
C00027949
|
| 4499 | MT1M, MT-1M, MT-IM, MT1, MT1K | metallothionein 1M |
C00027949
|
| 4502 | MT2A, MT2 | metallothionein 2A |
C00027949
|
| 4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00027949
|
| 22916 | NCBP2, CBC2, CBP20, NIP1 | nuclear cap binding protein subunit 2, 20kDa |
C00027949
|
| 10397 | NDRG1, CAP43, CMT4D, DRG-1, DRG1, GC4, HMSNL, NDR1, NMSL, PROXY1, RIT42, RTP, TARG1, TDD5 | N-myc downstream regulated 1 |
C00027949
|
| 100301851 |
C00027949
|
||
| 10528 | NOP56, NOL5A, SCA36 | NOP56 ribonucleoprotein |
C00027949
|
| 4898 | NRD1, hNRD1, hNRD2 | nardilysin (N-arginine dibasic convertase) (EC:3.4.24.61) |
C00027949
|
| 5033 | P4HA1, P4HA | prolyl 4-hydroxylase, alpha polypeptide I (EC:1.14.11.2) |
C00027949
|
| 5073 | PARN, DAN | poly(A)-specific ribonuclease (EC:3.1.13.4) |
C00027949
|
| 5154 | PDGFA, PDGF-A, PDGF1 | platelet-derived growth factor alpha polypeptide |
C00027949
|
| 5226 | PGD, 6PGD | phosphogluconate dehydrogenase (EC:1.1.1.44) |
C00027949
|
| 10424 | PGRMC2, DG6, PMBP | progesterone receptor membrane component 2 |
C00027949
|
| 29941 | PKN3, RP11-545E17.1 | protein kinase N3 (EC:2.7.11.13) |
C00027949
|
| 5521 | PPP2R2B, B55BETA, PP2AB55BETA, PP2ABBETA, PP2APR55B, PP2APR55BETA, PR2AB55BETA, PR2ABBETA, PR2APR55BETA, PR52B, PR55-BETA, PR55BETA, SCA12 | protein phosphatase 2, regulatory subunit B, beta (EC:3.1.3.16) |
C00027949
|
| 10084 | PQBP1, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS | polyglutamine binding protein 1 |
C00027949
|
| 465383 |
C00027949
|
||
| 9536 | PTGES, MGST-IV, MGST1-L1, MGST1L1, MPGES, PGES, PIG12, PP102, PP1294, TP53I12, mPGES-1 | prostaglandin E synthase (EC:5.3.99.3) |
C00027949
|
| 11031 | RAB31, Rab22B | RAB31, member RAS oncogene family |
C00027949
|
| 5950 | RBP4, RDCCAS | retinol binding protein 4, plasma |
C00027949
|
| 6191 | RPS4X, CCG2, DXS306, RPS4, S4, SCAR, SCR10 | ribosomal protein S4, X-linked |
C00027949
|
| 26156 | RSL1D1, CSIG, PBK1, UTP30 | ribosomal L1 domain containing 1 |
C00027949
|
| 8607 | RUVBL1, ECP54, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A | RuvB-like AAA ATPase 1 (EC:3.6.4.12) |
C00027949
|
| 6337 | SCNN1A, BESC2, ENaCa, ENaCalpha, SCNEA, SCNN1 | sodium channel, non-voltage-gated 1 alpha subunit |
C00027949
|
| 6385 | SDC4, SYND4 | syndecan 4 |
C00027949
|
| 6421 | SFPQ, POMP100, PSF | splicing factor proline/glutamine-rich |
C00027949
|
| 6446 | SGK1, SGK | serum/glucocorticoid regulated kinase 1 (EC:2.7.11.1) |
C00027949
|
| 8778 | SIGLEC5, CD170, CD33L2, OB-BP2, OBBP2, SIGLEC-5 | sialic acid binding Ig-like lectin 5 |
C00027949
|
| 79811 | SLTM, Met | SAFB-like, transcription modulator |
C00027949
|
| 9021 | SOCS3, ATOD4, CIS3, Cish3, SOCS-3, SSI-3, SSI3 | suppressor of cytokine signaling 3 |
C00027949
|
| 140809 | SRXN1, C20orf139, Npn3, SRX, SRX1 | sulfiredoxin 1 (EC:1.8.98.2) |
C00027949
|
| 6950 | TCP1, CCT-alpha, CCT1, CCTa, D6S230E, TCP-1-alpha | t-complex 1 |
C00027949
|
| 51372 | TMA7, CCDC72 | translation machinery associated 7 homolog (S. cerevisiae) |
C00027949
|
| 29058 | TMEM230, C20orf30, HSPC274, dJ1116H23.2.1 | transmembrane protein 230 |
C00027949
|
| 7171 | TPM4 | tropomyosin 4 |
C00027949
|
| 8848 | TSC22D1, Ptg-2, TGFB1I4, TSC22 | TSC22 domain family, member 1 |
C00027949
|
| 7378 | UPP1, UDRPASE, UP, UPASE, UPP | uridine phosphorylase 1 (EC:2.4.2.3) |
C00027949
|
| 57695 | USP37 | ubiquitin specific peptidase 37 (EC:3.4.19.12) |
C00027949
|
| 8409 | UXT, ART-27, STAP1 | ubiquitously-expressed, prefoldin-like chaperone |
C00027949
|
| 84215 | ZNF541 | zinc finger protein 541 |
C00027949
|