KCF-S cluster No. 6424 (1 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 1 |
Cumulative family count
| class name | count |
|---|---|
| Brassicaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001195
|
Mevalonic acid
|
CHEMBL1794734
|
D008798
|
65 / 0 |
|
Human Protein / Gene in interactions
65 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 27113 | BBC3, JFY-1, JFY1, PUMA | BCL2 binding component 3 |
C00001195
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00001195
|
| 650 | BMP2, BDA2, BMP2A | bone morphogenetic protein 2 |
C00001195
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00001195
|
| 840 | CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3 | caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60) |
C00001195
|
| 842 | CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 | caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) |
C00001195
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00001195
|
| 6348 | CCL3, G0S19-1, LD78ALPHA, MIP-1-alpha, MIP1A, SCYA3 | chemokine (C-C motif) ligand 3 |
C00001195
|
| 6351 | CCL4, ACT2, AT744.1, G-26, HC21, LAG-1, LAG1, MIP-1-beta, MIP1B, MIP1B1, SCYA2, SCYA4 | chemokine (C-C motif) ligand 4 |
C00001195
|
| 1230 | CCR1, CD191, CKR-1, CKR1, CMKBR1, HM145, MIP1aR, SCYAR1 | chemokine (C-C motif) receptor 1 |
C00001195
|
| 729230 | CCR2, CC-CKR-2, CCR-2, CCR2A, CCR2B, CD192, CKR2, CKR2A, CKR2B, CMKBR2, MCP-1-R | chemokine (C-C motif) receptor 2 |
C00001195
|
| 1233 | CCR4, CC-CKR-4, CD194, CKR4, CMKBR4, ChemR13, HGCN:14099, K5-5 | chemokine (C-C motif) receptor 4 |
C00001195
|
| 1234 | CCR5, CC-CKR-5, CCCKR5, CCR-5, CD195, CKR-5, CKR5, CMKBR5, IDDM22 | chemokine (C-C motif) receptor 5 (gene/pseudogene) |
C00001195
|
| 959 | CD40LG, CD154, CD40L, HIGM1, IGM, IMD3, T-BAM, TNFSF5, TRAP, gp39, hCD40L | CD40 ligand |
C00001195
|
| 960 | CD44, CDW44, CSPG8, ECMR-III, HCELL, HUTCH-I, IN, LHR, MC56, MDU2, MDU3, MIC4, Pgp1 | CD44 molecule (Indian blood group) |
C00001195
|
| 1063 | CENPF, CENF, PRO1779, hcp-1 | centromere protein F, 350/400kDa |
C00001195
|
| 1277 | COL1A1, OI4 | collagen, type I, alpha 1 |
C00001195
|
| 1401 | CRP, PTX1 | C-reactive protein, pentraxin-related |
C00001195
|
| 1906 | EDN1, ET1, HDLCQ7, PPET1 | endothelin 1 |
C00001195
|
| 2152 | F3, CD142, TF, TFA | coagulation factor III (thromboplastin, tissue factor) |
C00001195
|
| 3122 | HLA-DRA, HLA-DRA1, MLRW | major histocompatibility complex, class II, DR alpha |
C00001195
|
| 3156 | HMGCR, LDLCQ3 | 3-hydroxy-3-methylglutaryl-CoA reductase (EC:1.1.1.34) |
C00001195
|
| 3383 | ICAM1, BB2, CD54, P3.58 | intercellular adhesion molecule 1 |
C00001195
|
| 3458 | IFNG, IFG, IFI | interferon, gamma |
C00001195
|
| 3605 | IL17A, CTLA8, IL-17, IL-17A, IL17 | interleukin 17A |
C00001195
|
| 3552 | IL1A, IL-1A, IL1, IL1-ALPHA, IL1F1 | interleukin 1, alpha |
C00001195
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00001195
|
| 3569 | IL6, BSF2, HGF, HSF, IFNB2, IL-6 | interleukin 6 (interferon, beta 2) |
C00001195
|
| 3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00001195
|
| 10365 | KLF2, LKLF | Kruppel-like factor 2 |
C00001195
|
| 5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00001195
|
| 5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00001195
|
| 4312 | MMP1, CLG, CLGN | matrix metallopeptidase 1 (interstitial collagenase) (EC:3.4.24.7) |
C00001195
|
| 4318 | MMP9, CLG4B, GELB, MANDP2, MMP-9 | matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) |
C00001195
|
| 4586 | MUC5AC, MUC5, TBM, leB | mucin 5AC, oligomeric mucus/gel-forming |
C00001195
|
| 4790 | NFKB1, EBP-1, KBF1, NF-kB1, NF-kappa-B, NF-kappaB, NFKB-p105, NFKB-p50, NFkappaB, p105, p50 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 |
C00001195
|
| 4792 | NFKBIA, IKBA, MAD-3, NFKBI | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha |
C00001195
|
| 4846 | NOS3, ECNOS, eNOS | nitric oxide synthase 3 (endothelial cell) (EC:1.14.13.39) |
C00001195
|
| 8013 | NR4A3, CHN, CSMF, MINOR, NOR1, TEC | nuclear receptor subfamily 4, group A, member 3 |
C00001195
|
| 142 | PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 | poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) |
C00001195
|
| 5155 | PDGFB, IBGC5, PDGF-2, PDGF2, SIS, SSV, c-sis | platelet-derived growth factor beta polypeptide |
C00001195
|
| 5327 | PLAT, T-PA, TPA | plasminogen activator, tissue (EC:3.4.21.68) |
C00001195
|
| 5444 | PON1, ESA, MVCD5, PON | paraoxonase 1 (EC:3.1.1.2 3.1.8.1 3.1.1.81) |
C00001195
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00001195
|
| 5743 | PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1) |
C00001195
|
| 5879 | RAC1, Rac-1, TC-25, p21-Rac1 | ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) |
C00001195
|
| 5906 | RAP1A, KREV-1, KREV1, RAP1, SMGP21 | RAP1A, member of RAS oncogene family |
C00001195
|
| 5970 | RELA, NFKB3, p65 | v-rel avian reticuloendotheliosis viral oncogene homolog A |
C00001195
|
| 56729 | RETN, ADSF, FIZZ3, RETN1, RSTN, XCP1 | resistin |
C00001195
|
| 387 | RHOA, ARH12, ARHA, RHO12, RHOH12 | ras homolog family member A |
C00001195
|
| 388 | RHOB, ARH6, ARHB, MST081, MSTP081, RHOH6 | ras homolog family member B |
C00001195
|
| 6097 | RORC, NR1F3, RORG, RZR-GAMMA, RZRG, TOR | RAR-related orphan receptor C |
C00001195
|
| 6256 | RXRA, NR2B1 | retinoid X receptor, alpha |
C00001195
|
| 6401 | SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2 | selectin E |
C00001195
|
| 6721 | SREBF2, SREBP-2, SREBP2, bHLHd2 | sterol regulatory element binding transcription factor 2 |
C00001195
|
| 6772 | STAT1, CANDF7, ISGF-3, STAT91 | signal transducer and activator of transcription 1, 91kDa |
C00001195
|
| 6774 | STAT3, APRF, HIES | signal transducer and activator of transcription 3 (acute-phase response factor) |
C00001195
|
| 7054 | TH, DYT14, DYT5b, TYH | tyrosine hydroxylase (EC:1.14.16.2) |
C00001195
|
| 7056 | THBD, AHUS6, BDCA3, CD141, THPH12, THRM, TM | thrombomodulin |
C00001195
|
| 7124 | TNF, DIF, TNF-alpha, TNFA, TNFSF2 | tumor necrosis factor |
C00001195
|
| 7293 | TNFRSF4, ACT35, CD134, OX40, TXGP1L | tumor necrosis factor receptor superfamily, member 4 |
C00001195
|
| 8743 | TNFSF10, APO2L, Apo-2L, CD253, TL2, TRAIL | tumor necrosis factor (ligand) superfamily, member 10 |
C00001195
|
| 7292 | TNFSF4, CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1 | tumor necrosis factor (ligand) superfamily, member 4 |
C00001195
|
| 7412 | VCAM1, CD106, INCAM-100 | vascular cell adhesion molecule 1 |
C00001195
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00001195
|