| class name | count |
|---|---|
| rosids | 1 |
| class name | count |
|---|---|
| Plectosphaerellaceae | 8 |
| Cordycipitaceae | 2 |
| Cortinariaceae | 2 |
| Rhamnaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00002999
|
Karwinskione
|
|
||||
|
C00015905
|
ES-242-4 atropisomer
|
CHEMBL399293
|
30 / 25 / 20 |
|
||
|
C00015906
|
ES-242-5 atropisomer
|
|
||||
|
C00016706
|
ES-242-2
|
CHEMBL269531
|
|
|||
|
C00016707
|
ES-242-3
|
|
||||
|
C00016708
|
ES-242-4
|
CHEMBL399293
|
30 / 25 / 20 |
|
||
|
C00016709
|
ES-242-5
|
|
||||
|
C00016710
|
ES-242-6
|
|
||||
|
C00016711
|
ES-242-7
|
|
||||
|
C00016712
|
ES-242-8
|
|
||||
|
C00017219
|
ES 242-1
|
C073561
|
|
|||
|
C00035532
|
Austrocolorin A1
|
|
||||
|
C00035533
|
Austrocolorin B1
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q07820 | Induced myeloid leukemia cell differentiation protein Mcl-1 | Other cytosolic protein | C00015905 C00016708 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00015905 C00016708 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00015905 C00016708 | 2 / 0 |
| P06746 | DNA polymerase beta | Enzyme | C00015905 C00016708 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00015905 C00016708 | 0 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00015905 C00016708 | 4 / 2 |
| P54132 | Bloom syndrome protein | Enzyme | C00015905 C00016708 | 1 / 2 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00015905 C00016708 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00015905 C00016708 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00015905 C00016708 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00015905 C00016708 | 7 / 3 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00015905 C00016708 | 1 / 1 |
| Q9Y468 | Lethal(3)malignant brain tumor-like protein 1 | Unclassified protein | C00015905 C00016708 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00015905 C00016708 | 1 / 2 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00015905 C00016708 | 1 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00015905 C00016708 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00015905 C00016708 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00015905 C00016708 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00015905 C00016708 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00015905 C00016708 | 4 / 3 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00015905 C00016708 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00015905 C00016708 | 0 / 0 |
| P46063 | ATP-dependent DNA helicase Q1 | Enzyme | C00015905 C00016708 | 0 / 0 |
| O00255 | Menin | Unclassified protein | C00015905 C00016708 | 2 / 5 |
| Q02410 | Amyloid beta A4 precursor protein-binding family A member 1 | Unclassified protein | C00015905 C00016708 | 0 / 0 |
| Q00975 | Voltage-dependent N-type calcium channel subunit alpha-1B | N-TYPE | C00015905 C00016708 | 0 / 0 |
| Q9UBT2 | SUMO-activating enzyme subunit 2 | Enzyme | C00015905 C00016708 | 0 / 0 |
| Q9UBE0 | SUMO-activating enzyme subunit 1 | Unclassified protein | C00015905 C00016708 | 0 / 0 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00015905 C00016708 | 0 / 0 |
| Q14191 | Werner syndrome ATP-dependent helicase | Enzyme | C00015905 C00016708 | 2 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #210900 | Bloom syndrome; blm |
P54132
|
| #114500 | Colorectal cancer; crc |
Q14191
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277700 | Werner syndrome; wrn |
Q14191
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00094 | DNA repair defects |
P54132
(related)
|
| H00296 | Defects in RecQ helicases |
P54132
(related)
Q14191 (related) |
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|