Plant Species


Cumulative plant class count

class name count
rosids 1

Cumulative family count

class name count
Plectosphaerellaceae 8
Cordycipitaceae 2
Cortinariaceae 2
Rhamnaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (13)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00002999 External link 512 Karwinskione
C00015905 External link 512 ES-242-4 atropisomer
CHEMBL399293
30 / 25 / 20
C00015906 External link 512 ES-242-5 atropisomer
C00016706 External link 512 ES-242-2
CHEMBL269531
C00016707 External link 512 ES-242-3
C00016708 External link 512 ES-242-4
CHEMBL399293
30 / 25 / 20
C00016709 External link 512 ES-242-5
C00016710 External link 512 ES-242-6
C00016711 External link 512 ES-242-7
C00016712 External link 512 ES-242-8
C00017219 External link 512 ES 242-1
C073561
C00035532 External link 512 Austrocolorin A1
C00035533 External link 512 Austrocolorin B1

Human Protein / Gene in interactions

30 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q07820 Induced myeloid leukemia cell differentiation protein Mcl-1 Other cytosolic protein C00015905 C00016708 0 / 0
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00015905 C00016708 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00015905 C00016708 2 / 0
P06746 DNA polymerase beta Enzyme C00015905 C00016708 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00015905 C00016708 0 / 0
P37840 Alpha-synuclein Unclassified protein C00015905 C00016708 4 / 2
P54132 Bloom syndrome protein Enzyme C00015905 C00016708 1 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00015905 C00016708 0 / 0
P39748 Flap endonuclease 1 Enzyme C00015905 C00016708 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00015905 C00016708 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00015905 C00016708 7 / 3
Q9Y253 DNA polymerase eta Enzyme C00015905 C00016708 1 / 1
Q9Y468 Lethal(3)malignant brain tumor-like protein 1 Unclassified protein C00015905 C00016708 0 / 0
P11308 Transcriptional regulator ERG Unclassified protein C00015905 C00016708 1 / 2
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00015905 C00016708 1 / 2
P83916 Chromobox protein homolog 1 Unclassified protein C00015905 C00016708 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00015905 C00016708 0 / 0
O75164 Lysine-specific demethylase 4A Enzyme C00015905 C00016708 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00015905 C00016708 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00015905 C00016708 4 / 3
Q9UBT6 DNA polymerase kappa Enzyme C00015905 C00016708 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00015905 C00016708 0 / 0
P46063 ATP-dependent DNA helicase Q1 Enzyme C00015905 C00016708 0 / 0
O00255 Menin Unclassified protein C00015905 C00016708 2 / 5
Q02410 Amyloid beta A4 precursor protein-binding family A member 1 Unclassified protein C00015905 C00016708 0 / 0
Q00975 Voltage-dependent N-type calcium channel subunit alpha-1B N-TYPE C00015905 C00016708 0 / 0
Q9UBT2 SUMO-activating enzyme subunit 2 Enzyme C00015905 C00016708 0 / 0
Q9UBE0 SUMO-activating enzyme subunit 1 Unclassified protein C00015905 C00016708 0 / 0
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00015905 C00016708 0 / 0
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00015905 C00016708 2 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (25)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#210900 Bloom syndrome; blm P54132
#114500 Colorectal cancer; crc Q14191
#127750 Dementia, lewy body; dlb P37840
#612219 Ewing sarcoma; es P11308
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#174800 Mccune-albright syndrome; mas P63092
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#166350 Osseous heteroplasia, progressive; poh P63092
#168601 Parkinson disease 1, autosomal dominant; park1 P37840
#605543 Parkinson disease 4, autosomal dominant; park4 P37840
#168600 Parkinson disease, late-onset; pd P37840
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277700 Werner syndrome; wrn Q14191
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (20)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00024 Prostate cancer P11308 (related)
H00035 Ewing's sarcoma P11308 (related)
H00057 Parkinson's disease (PD) P37840 (related)
H00066 Lewy body dementia (LBD) P37840 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
Q14191 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)