KCF-S cluster No. 6732 (1 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (1)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

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Cumulative plant class count

class name	count

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Cumulative family count

class name	count
Bovidae	1

KEGG BRITE br08003

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Categories (0)

br08003 Category	# of metabolite

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metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (1)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00029828	Bilirubin / (Z,Z)-Bilirubin	CHEMBL501680	D001663	22 / 31 / 28	155 / 20

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P22310	UDP-glucuronosyltransferase 1-4	Enzyme	C00029828	3 / 0
O75795	UDP-glucuronosyltransferase 2B17	Enzyme	C00029828	1 / 0
Q9Y6L6	Solute carrier organic anion transporter family member 1B1	Electrochemical transporter	C00029828	1 / 0
P29466	Caspase-1	C14	C00029828	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00029828	11 / 10
P16662	UDP-glucuronosyltransferase 2B7	Enzyme	C00029828	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00029828	2 / 3
P00352	Retinal dehydrogenase 1	Enzyme	C00029828	0 / 0
P46721	Solute carrier organic anion transporter family member 1A2	Unclassified protein	C00029828	0 / 0
O60656	UDP-glucuronosyltransferase 1-9	Enzyme	C00029828	0 / 0
Q9NPD5	Solute carrier organic anion transporter family member 1B3	Electrochemical transporter	C00029828	1 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00029828	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00029828	3 / 3
P55210	Caspase-7	C14	C00029828	0 / 0
P22309	UDP-glucuronosyltransferase 1-1	Enzyme	C00029828	5 / 1
P10636	Microtubule-associated protein tau	Unclassified protein	C00029828	4 / 3
P19224	UDP-glucuronosyltransferase 1-6	Enzyme	C00029828	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00029828	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00029828	0 / 0
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00029828	1 / 1
O00255	Menin	Unclassified protein	C00029828	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00029828	1 / 2

155 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
4363	ABCC1, ABC29, ABCC, GS-X, MRP, MRP1	ATP-binding cassette, sub-family C (CFTR/MRP), member 1	C00029828
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00029828
210	ALAD, ALADH, PBGS	aminolevulinate dehydratase (EC:4.2.1.24)	C00029828
301	ANXA1, ANX1, LPC1	annexin A1	C00029828
374	AREG, AR, CRDGF, SDGF	amphiregulin	C00029828
9411	ARHGAP29, PARG1, RP11-255E17.1	Rho GTPase activating protein 29	C00029828
79754	ASB13	ankyrin repeat and SOCS box containing 13	C00029828
467	ATF3	activating transcription factor 3	C00029828
476	ATP1A1	ATPase, Na+/K+ transporting, alpha 1 polypeptide (EC:3.6.3.9)	C00029828
8313	AXIN2, AXIL, ODCRCS	axin 2	C00029828
2647	BLOC1S1, BLOS1, GCN5L1, MICoA, RT14	biogenesis of lysosomal organelles complex-1, subunit 1	C00029828
10438	C1D, LRP1, SUN-CoR, SUNCOR, hC1D	C1D nuclear receptor corepressor	C00029828
847	CAT	catalase (EC:1.11.1.6)	C00029828
151887	CCDC80, DRO1, SSG1, URB, okuribin	coiled-coil domain containing 80	C00029828
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00029828
25819	CCRN4L, CCR4L, NOC	CCR4 carbon catabolite repression 4-like (S. cerevisiae)	C00029828
9936	CD302, BIMLEC, CLEC13A, DCL-1, DCL1	CD302 molecule	C00029828
79094	CHAC1	ChaC, cation transport regulator homolog 1 (E. coli)	C00029828
1119	CHKA, CHK, CK, CKI, EK	choline kinase alpha (EC:2.7.1.32 2.7.1.82)	C00029828
23155	CLCC1, MCLC	chloride channel CLIC-like 1	C00029828
6249	CLIP1, CLIP, CLIP-170, CLIP170, CYLN1, RSN	CAP-GLY domain containing linker protein 1	C00029828
1281	COL3A1, EDS4A	collagen, type III, alpha 1	C00029828
1355	COX15, CEMCOX2	cytochrome c oxidase assembly homolog 15 (yeast)	C00029828
1362	CPD, GP180	carboxypeptidase D (EC:3.4.17.22)	C00029828
1437	CSF2, GMCSF	colony stimulating factor 2 (granulocyte-macrophage)	C00029828
1512	CTSH, ACC-4, ACC-5, CPSB, minichain	cathepsin H (EC:3.4.22.16)	C00029828
3627	CXCL10, C7, IFI10, INP10, IP-10, SCYB10, crg-2, gIP-10, mob-1	chemokine (C-X-C motif) ligand 10	C00029828
6373	CXCL11, H174, I-TAC, IP-9, IP9, SCYB11, SCYB9B, b-R1	chemokine (C-X-C motif) ligand 11	C00029828
2920	CXCL2, CINC-2a, GRO2, GROb, MGSA-b, MIP-2a, MIP2, MIP2A, SCYB2	chemokine (C-X-C motif) ligand 2	C00029828
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00029828
1548	CYP2A6, CPA6, CYP2A, CYP2A3, CYPIIA6, P450C2A, P450PB	cytochrome P450, family 2, subfamily A, polypeptide 6 (EC:1.14.14.1)	C00029828
1555	CYP2B6, CPB6, CYP2B, CYP2B7, CYP2B7P, CYPIIB6, EFVM, IIB1, P450	cytochrome P450, family 2, subfamily B, polypeptide 6 (EC:1.14.14.1)	C00029828
1559	CYP2C9, CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9	cytochrome P450, family 2, subfamily C, polypeptide 9 (EC:1.14.13.48 1.14.13.49 1.14.13.80)	C00029828
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00029828
1649	DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153	DNA-damage-inducible transcript 3	C00029828
420357			C00029828
93099	DMKN, UNQ729, ZD52F10	dermokine	C00029828
3337	DNAJB1, HSPF1, Hdj1, Hsp40, RSPH16B, Sis1	DnaJ (Hsp40) homolog, subfamily B, member 1	C00029828
23549	DNPEP, ASPEP, DAP	aspartyl aminopeptidase (EC:3.4.11.21)	C00029828
23333	DPY19L1	dpy-19-like 1 (C. elegans)	C00029828
1847	DUSP5, DUSP, HVH3	dual specificity phosphatase 5 (EC:3.1.3.16 3.1.3.48)	C00029828
54583	EGLN1, C1orf12, ECYT3, HIF-PH2, HIFPH2, HPH-2, HPH2, PHD2, SM20, ZMYND6	egl-9 family hypoxia-inducible factor 1 (EC:1.14.11.29)	C00029828
9538	EI24, EPG4, PIG8, TP53I8	etoposide induced 2.4	C00029828
23741	EID1, C15orf3, CRI1, EID-1, IRO45620, PTD014, RBP21	EP300 interacting inhibitor of differentiation 1	C00029828
9451	EIF2AK3, PEK, PERK, WRS	eukaryotic translation initiation factor 2-alpha kinase 3 (EC:2.7.11.1)	C00029828
1965	EIF2S1, EIF-2, EIF-2A, EIF-2alpha, EIF2, EIF2A	eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa	C00029828
23052	ENDOD1	endonuclease domain containing 1	C00029828
345757	FAM174A, TMEM157, UNQ1912	family with sequence similarity 174, member A	C00029828
8061	FOSL1, FRA, FRA1, fra-1	FOS-like antigen 1	C00029828
4616	GADD45B, GADD45BETA, MYD118	growth arrest and DNA-damage-inducible, beta	C00029828
60674	GAS5, NCRNA00030, SNHG2	growth arrest-specific 5 (non-protein coding)	C00029828
2934	GSN, ADF, AGEL	gelsolin	C00029828
2938	GSTA1, GST2, GSTA1-1, GTH1	glutathione S-transferase alpha 1 (EC:2.5.1.18)	C00029828
2939	GSTA2, GST2, GSTA2-2, GTA2, GTH2	glutathione S-transferase alpha 2 (EC:2.5.1.18)	C00029828
2940	GSTA3, GSTA3-3, GTA3	glutathione S-transferase alpha 3 (EC:2.5.1.18)	C00029828
2941	GSTA4, GSTA4-4, GTA4	glutathione S-transferase alpha 4 (EC:2.5.1.18)	C00029828
373156	GSTK1, GST, GST_13-13, GST13, GST13-13, GSTK1-1, hGSTK1	glutathione S-transferase kappa 1 (EC:2.5.1.18)	C00029828
2944	GSTM1, GST1, GSTM1-1, GSTM1a-1a, GSTM1b-1b, GTH4, GTM1, H-B, MU, MU-1	glutathione S-transferase mu 1 (EC:2.5.1.18)	C00029828
2950	GSTP1, DFN7, FAEES3, GST3, GSTP, PI	glutathione S-transferase pi 1 (EC:2.5.1.18)	C00029828
9843	HEPH, CPL	hephaestin	C00029828
9709	HERPUD1, HERP, Mif1, SUP	homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1	C00029828
3008	HIST1H1E, H1.4, H1E, H1F4, H1s-4, dJ221C16.5	histone cluster 1, H1e	C00029828
8347	HIST1H2BC, H2B.1, H2B/l, H2BFL, dJ221C16.3	histone cluster 1, H2bc	C00029828
319188			C00029828
8294	HIST1H4I, H4/m, H4FM, H4M	histone cluster 1, H4i	C00029828
97114			C00029828
92815	HIST3H2A	histone cluster 3, H2a	C00029828
3162	HMOX1, HMOX1D, HO-1, HSP32, bK286B10	heme oxygenase (decycling) 1 (EC:1.14.99.3)	C00029828
373300			C00029828
3309	HSPA5, BIP, GRP78, MIF2	heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	C00029828
3418	IDH2, D2HGA2, ICD-M, IDH, IDHM, IDP, IDPM, mNADP-IDH	isocitrate dehydrogenase 2 (NADP+), mitochondrial (EC:1.1.1.42)	C00029828
3475	IFRD1, PC4, TIS7	interferon-related developmental regulator 1	C00029828
3486	IGFBP3, BP-53, IBP3	insulin-like growth factor binding protein 3	C00029828
3606	IL18, IGIF, IL-18, IL-1g, IL1F4	interleukin 18 (interferon-gamma-inducing factor)	C00029828
3553	IL1B, IL-1, IL1-BETA, IL1F2	interleukin 1, beta	C00029828
3569	IL6, BSF2, HGF, HSF, IFNB2, IL-6	interleukin 6 (interferon, beta 2)	C00029828
3912	LAMB1, CLM, LIS5	laminin, beta 1	C00029828
3920	LAMP2, CD107b, LAMP-2, LAMPB, LGP110	lysosomal-associated membrane protein 2	C00029828
54741	LEPROT, LEPR, OB-RGRP, OBRGRP, VPS55	leptin receptor overlapping transcript	C00029828
3976	LIF, CDF, DIA, HILDA, MLPLI	leukemia inhibitory factor	C00029828
4035	LRP1, A2MR, APOER, APR, CD91, IGFBP3R, LRP, LRP1A, TGFBR5	low density lipoprotein receptor-related protein 1	C00029828
110454			C00029828
4094	MAF, CCA4, c-MAF	v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog	C00029828
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00029828
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00029828
10982	MAPRE2, EB1, EB2, RP1	microtubule-associated protein, RP/EB family, member 2	C00029828
4200	ME2, ODS1	malic enzyme 2, NAD(+)-dependent, mitochondrial (EC:1.1.1.38)	C00029828
1955	MEGF9, EGFL5	multiple EGF-like-domains 9	C00029828
4258	MGST2, GST2, MGST-II	microsomal glutathione S-transferase 2 (EC:2.5.1.18)	C00029828
4322	MMP13, CLG3, MANDP1	matrix metallopeptidase 13 (collagenase 3) (EC:3.4.24.-)	C00029828
10205	MPZL2, EVA, EVA1	myelin protein zero-like 2	C00029828
29074	MRPL18, L18mt, MRP-L18	mitochondrial ribosomal protein L18	C00029828
4811	NID1, NID	nidogen 1	C00029828
23530	NNT, GCCD4	nicotinamide nucleotide transhydrogenase (EC:1.6.1.2)	C00029828
8856	NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR	nuclear receptor subfamily 1, group I, member 2	C00029828
9970	NR1I3, CAR, CAR1, MB67	nuclear receptor subfamily 1, group I, member 3	C00029828
29948	OSGIN1, BDGI, OKL38	oxidative stress induced growth inhibitor 1	C00029828
5163	PDK1	pyruvate dehydrogenase kinase, isozyme 1 (EC:2.7.11.2)	C00029828
27315	PGAP2, CWH43-N, FRAG1, HPMRS3, MRT17, MRT21	post-GPI attachment to proteins 2	C00029828
5245	PHB, PHB1	prohibitin	C00029828
8554	PIAS1, DDXBP1, GBP, GU/RH-II, ZMIZ3	protein inhibitor of activated STAT, 1	C00029828
5295	PIK3R1, AGM7, GRB1, p85, p85-ALPHA	phosphoinositide-3-kinase, regulatory subunit 1 (alpha)	C00029828
18722			C00029828
51365	PLA1A, PS-PLA1, PSPLA1	phospholipase A1 member A (EC:3.1.1.-)	C00029828
5376	PMP22, CMT1A, CMT1E, DSS, GAS-3, HMSNIA, HNPP, Sp110	peripheral myelin protein 22	C00029828
5445	PON2	paraoxonase 2 (EC:3.1.1.2 3.1.1.81)	C00029828
10549	PRDX4, AOE37-2, PRX-4	peroxiredoxin 4 (EC:1.11.1.15)	C00029828
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00029828
401494	PTPLAD2, HACD4	protein tyrosine phosphatase-like A domain containing 2 (EC:4.2.1.134)	C00029828
83937	RASSF4, AD037	Ras association (RalGDS/AF-6) domain family member 4	C00029828
9584	RBM39, CAPER, CAPERalpha, FSAP59, HCC1, RNPC2	RNA binding motif protein 39	C00029828
10181	RBM5, G15, LUCA15, RMB5	RNA binding motif protein 5	C00029828
22836	RHOBTB3	Rho-related BTB domain containing 3	C00029828
6038	RNASE4, RNS4	ribonuclease, RNase A family, 4 (EC:3.1.27.-)	C00029828
6281	S100A10, 42C, ANX2L, ANX2LG, CAL1L, CLP11, Ca[1], GP11, P11, p10	S100 calcium binding protein A10	C00029828
6275	S100A4, 18A2, 42A, CAPL, FSP1, MTS1, P9KA, PEL98	S100 calcium binding protein A4	C00029828
6342	SCP2, NLTP, NSL-TP, SCP-2, SCP-CHI, SCP-X, SCPX	sterol carrier protein 2 (EC:2.3.1.176)	C00029828
8991	SELENBP1, LPSB, SBP56, SP56, hSBP	selenium binding protein 1	C00029828
66222			C00029828
5054	SERPINE1, PAI, PAI-1, PAI1, PLANH1	serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1	C00029828
27244	SESN1, PA26, SEST1	sestrin 1	C00029828
81537	SGPP1, SPPase1	sphingosine-1-phosphate phosphatase 1	C00029828
387700	SLC16A12, CJMG, MCT12	solute carrier family 16, member 12	C00029828
9963	SLC23A1, SLC23A2, SVCT1, YSPL3	solute carrier family 23 (ascorbic acid transporter), member 1	C00029828
9962	SLC23A2, NBTL1, SLC23A1, SVCT2, YSPL2	solute carrier family 23 (ascorbic acid transporter), member 2	C00029828
6520	SLC3A2, 4F2, 4F2HC, 4T2HC, CD98, CD98HC, MDU1, NACAE	solute carrier family 3 (amino acid transporter heavy chain), member 2	C00029828
23657	SLC7A11, CCBR1, xCT	solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11	C00029828
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00029828
57231	SNX14, RGS-PX2	sorting nexin 14	C00029828
50964	SOST, CDD, VBCH	sclerostin	C00029828
389058	SP5	Sp5 transcription factor	C00029828
73526			C00029828
6892	TAPBP, NGS17, TAPA, TPN, TPSN	TAP binding protein (tapasin)	C00029828
6925	TCF4, E2-2, ITF-2, ITF2, PTHS, SEF-2, SEF2, SEF2-1, SEF2-1A, SEF2-1B, TCF-4, bHLHb19	transcription factor 4	C00029828
25976	TIPARP, ARTD14, PARP7, pART14	TCDD-inducible poly(ADP-ribose) polymerase (EC:2.4.2.30)	C00029828
9375	TM9SF2, P76	transmembrane 9 superfamily member 2	C00029828
55504	TNFRSF19, TAJ, TAJ-alpha, TRADE, TROY	tumor necrosis factor receptor superfamily, member 19	C00029828
1200	TPP1, CLN2, LPIC, TPP-1	tripeptidyl peptidase I (EC:3.4.14.9)	C00029828
28951	TRIB2, C5FW, GS3955, TRB2	tribbles pseudokinase 2	C00029828
7329	UBE2I, C358B7.1, P18, UBC9	ubiquitin-conjugating enzyme E2I (EC:6.3.2.19)	C00029828
54658	UGT1A1, BILIQTL1, GNT1, HUG-BR1, UDPGT, UDPGT_1-1, UGT1, UGT1A	UDP glucuronosyltransferase 1 family, polypeptide A1 (EC:2.4.1.17)	C00029828
54659	UGT1A3, UDPGT, UDPGT_1-3, UGT-1C, UGT1-03, UGT1.3, UGT1C	UDP glucuronosyltransferase 1 family, polypeptide A3 (EC:2.4.1.17)	C00029828
7366	UGT2B15, HLUG4, UDPGT_2B8, UDPGT2B15, UDPGTH3, UGT2B8	UDP glucuronosyltransferase 2 family, polypeptide B15 (EC:2.4.1.17)	C00029828
708396			C00029828
7381	UQCRB, MC3DN3, QCR7, QP-C, QPC, UQBC, UQBP, UQCR6, UQPC	ubiquinol-cytochrome c reductase binding protein (EC:1.10.2.2)	C00029828
7384	UQCRC1, D3S3191, QCR1, UQCR1	ubiquinol-cytochrome c reductase core protein I (EC:1.10.2.2)	C00029828
7388	UQCRH, QCR6, UQCR8	ubiquinol-cytochrome c reductase hinge protein (EC:1.10.2.2)	C00029828
80146	UXS1, SDR6E1, UGD	UDP-glucuronate decarboxylase 1 (EC:4.1.1.35)	C00029828
7436	VLDLR, CARMQ1, CHRMQ1, VLDLRCH	very low density lipoprotein receptor	C00029828
26137	ZBTB20, DPZF, HOF, ODA-8S, ZNF288	zinc finger and BTB domain containing 20	C00029828
339487	ZBTB8OS, ARCH, ARCH2	zinc finger and BTB domain containing 8 opposite strand	C00029828
84186	ZCCHC7, AIR1, RP11-397D12.1	zinc finger, CCHC domain containing 7	C00029828
90637	ZFAND2A, AIRAP	zinc finger, AN1-type domain 2A	C00029828
22680			C00029828
24132			C00029828

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions