| class name | count |
|---|---|
| rosids | 1 |
| class name | count |
|---|---|
| Brassicaceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00007301
|
Urate
/ Uric acid |
CHEMBL792
CHEMBL1951298 |
D014527
|
3 / 0 / 0 | 39 / 16 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q9Y2T3 | Guanine deaminase | Enzyme | C00007301 | 0 / 0 |
| Q8TCC7 | Solute carrier family 22 member 8 | Antiporter | C00007301 | 0 / 0 |
| Q4U2R8 | Solute carrier family 22 member 6 | Antiporter | C00007301 | 0 / 0 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 29974 | A1CF, ACF, ACF64, ACF65, APOBEC1CF, ASP | APOBEC1 complementation factor |
C00007301
|
| 10257 | ABCC4, EST170205, MOAT-B, MOATB, MRP4 | ATP-binding cassette, sub-family C (CFTR/MRP), member 4 |
C00007301
|
| 210 | ALAD, ALADH, PBGS | aminolevulinate dehydratase (EC:4.2.1.24) |
C00007301
|
| 126133 | ALDH16A1 | aldehyde dehydrogenase 16 family, member A1 |
C00007301
|
| 358 | AQP1, AQP-CHIP, CHIP28, CO | aquaporin 1 |
C00007301
|
| 366 | AQP9, AQP-9, HsT17287, SSC1 | aquaporin 9 |
C00007301
|
| 468 | ATF4, CREB-2, CREB2, TAXREB67, TXREB | activating transcription factor 4 |
C00007301
|
| 6311 | ATXN2, ASL13, ATX2, SCA2, TNRC13 | ataxin 2 |
C00007301
|
| 79369 | B3GNT4, B3GN-T4, beta3Gn-T4 | UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 4 |
C00007301
|
| 9031 | BAZ1B, WBSCR10, WBSCR9, WSTF | bromodomain adjacent to zinc finger domain, 1B (EC:2.7.10.2) |
C00007301
|
| 834 | CASP1, ICE, IL1BC, P45 | caspase 1, apoptosis-related cysteine peptidase (EC:3.4.22.36) |
C00007301
|
| 6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00007301
|
| 1356 | CP, CP-2 | ceruloplasmin (ferroxidase) (EC:1.16.3.1) |
C00007301
|
| 1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00007301
|
| 3131 | HLF | hepatic leukemia factor |
C00007301
|
| 3174 | HNF4G, NR2A2, NR2A3 | hepatocyte nuclear factor 4, gamma |
C00007301
|
| 3480 | IGF1R, CD221, IGFIR, IGFR, JTK13 | insulin-like growth factor 1 receptor (EC:2.7.10.1) |
C00007301
|
| 3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00007301
|
| 3625 | INHBB | inhibin, beta B |
C00007301
|
| 3708 | ITPR1, INSP3R1, IP3R, IP3R1, SCA15, SCA16, SCA29 | inositol 1,4,5-trisphosphate receptor, type 1 |
C00007301
|
| 4094 | MAF, CCA4, c-MAF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog |
C00007301
|
| 10725 | NFAT5, NF-AT5, NFATL1, NFATZ, OREBP, TONEBP | nuclear factor of activated T-cells 5, tonicity-responsive |
C00007301
|
| 114548 | NLRP3, AGTAVPRL, AII, AVP, C1orf7, CIAS1, CLR1.1, FCAS, FCU, MWS, NALP3, PYPAF1 | NLR family, pyrin domain containing 3 |
C00007301
|
| 51422 | PRKAG2, AAKG, AAKG2, CMH6, H91620p, WPWS | protein kinase, AMP-activated, gamma 2 non-catalytic subunit |
C00007301
|
| 51460 | SFMBT1, RU1, SFMBT, hSFMBT | Scm-like with four mbt domains 1 |
C00007301
|
| 10786 | SLC17A3, NPT4 | solute carrier family 17 (organic anion transporter), member 3 |
C00007301
|
| 55867 | SLC22A11, OAT4, hOAT4 | solute carrier family 22 (organic anion/urate transporter), member 11 |
C00007301
|
| 116085 | SLC22A12, OAT4L, RST, URAT1 | solute carrier family 22 (organic anion/urate transporter), member 12 |
C00007301
|
| 9356 | SLC22A6, HOAT1, OAT1, PAHT, ROAT1 | solute carrier family 22 (organic anion transporter), member 6 |
C00007301
|
| 9376 | SLC22A8, OAT3 | solute carrier family 22 (organic anion transporter), member 8 |
C00007301
|
| 56606 | SLC2A9, GLUT9, GLUTX, UAQTL2, URATv1 | solute carrier family 2 (facilitated glucose transporter), member 9 |
C00007301
|
| 6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00007301
|
| 6781 | STC1, STC | stanniocalcin 1 |
C00007301
|
| 134285 | TMEM171, PRP2 | transmembrane protein 171 |
C00007301
|
| 80128 | TRIM46, GENEY, TRIFIC | tripartite motif containing 46 |
C00007301
|
| 92912 | UBE2Q2 | ubiquitin-conjugating enzyme E2Q family member 2 (EC:6.3.2.19) |
C00007301
|
| 391051 | UOX, UOXP, URICASE | urate oxidase, pseudogene |
C00007301
|
| 7422 | VEGFA, MVCD1, VEGF, VPF | vascular endothelial growth factor A |
C00007301
|
| 7498 | XDH, XO, XOR | xanthine dehydrogenase (EC:1.17.1.4 1.17.3.2) |
C00007301
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D000740 | Anemia |
C00007301
|
| D015210 | Arthritis, Gouty |
C00007301
|
| D002310 | Cardiomyopathy, Alcoholic |
C00007301
|
| D002779 | Cholestasis |
C00007301
|
| D003922 | Diabetes Mellitus, Type 1 |
C00007301
|
| D006073 | Gout |
C00007301
|
| D033461 | Hyperuricemia |
C00007301
|
| D007249 | Inflammation |
C00007301
|
| D007669 | Kidney Calculi |
C00007301
|
| D007674 | Kidney Diseases |
C00007301
|
| D007970 | Leukopenia |
C00007301
|
| D008659 | Metabolic Diseases |
C00007301
|
| D024821 | Metabolic Syndrome X |
C00007301
|
| D010146 | Pain |
C00007301
|
| D052878 | Urolithiasis |
C00007301
|
| D014652 | Vascular Diseases |
C00007301
|