PCIDB

KCF-S cluster No. 7202 (1 metabolites)

Plant Species

Cumulative plant class count

class name count
rosids 4

Cumulative family count

class name count
Fabaceae 3
Brassicaceae 1
Enterobacteriaceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00001363 External link 512 L-Histidine
CHEMBL17962
CHEMBL104875
25 / 9 / 16

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001363 1 / 0
Q9Y2D0 Carbonic anhydrase 5B, mitochondrial Lyase C00001363 0 / 0
P35218 Carbonic anhydrase 5A, mitochondrial Lyase C00001363 0 / 0
P43166 Carbonic anhydrase 7 Lyase C00001363 0 / 0
P00918 Carbonic anhydrase 2 Lyase C00001363 1 / 2
P42357 Histidine ammonia-lyase Enzyme C00001363 1 / 1
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001363 0 / 1
P23280 Carbonic anhydrase 6 Lyase C00001363 0 / 0
Q9ULX7 Carbonic anhydrase 14 Lyase C00001363 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00001363 0 / 0
O43570 Carbonic anhydrase 12 Lyase C00001363 1 / 2
P39748 Flap endonuclease 1 Enzyme C00001363 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00001363 0 / 0
P00915 Carbonic anhydrase 1 Lyase C00001363 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001363 0 / 0
Q16790 Carbonic anhydrase 9 Lyase C00001363 0 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00001363 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001363 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001363 0 / 1
P07451 Carbonic anhydrase 3 Lyase C00001363 0 / 0
P22748 Carbonic anhydrase 4 Lyase C00001363 1 / 1
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001363 0 / 0
O00255 Menin Unclassified protein C00001363 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00001363 1 / 2
Q05BR4 SLC16A10 protein Unclassified protein C00001363 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#235800 Histidinemia P42357
#143860 Hyperchlorhidrosis, isolated O43570
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#600852 Retinitis pigmentosa 17; rp17 P22748

KEGG DISEASE (16)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H01302 Hyperchlorhidrosis isolated (HCHLH) O43570 (related)
H00021 Renal cell carcinoma O43570 (marker)
Q16790 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00527 Retinitis pigmentosa (RP) P22748 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00171 Histidinemia P42357 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)