| class name | count |
|---|
| class name | count |
|---|---|
| Davidiellaceae | 5 |
| Aspergillaceae | 2 |
| Arthrodermataceae | 1 |
| br08003 Category | # of metabolite |
|---|
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00018557
|
3,11-Diketofusidic acid
|
C029031
|
|
|||
|
C00023894
|
Viridominic acid A
|
|
||||
|
C00023895
|
Viridominic acid B
|
|
||||
|
C00023896
|
Viridominic acid C
|
|
||||
|
C00023897
|
Cephalosporin P1
|
|
||||
|
C00023903
|
Fusidic acid
|
CHEMBL117110
CHEMBL383466 CHEMBL374975 CHEMBL1334456 CHEMBL1477084 CHEMBL1552107 CHEMBL1619349 CHEMBL1620692 CHEMBL1625992 CHEMBL2068923 |
D005672
|
10 / 11 / 11 | 1 / 14 |
|
|
C00023904
|
Fumigacin
/ Helvolic acid |
CHEMBL505132
|
C011267
|
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P02768 | Serum albumin | Secreted protein | C00023903 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00023903 | 2 / 3 |
| P39748 | Flap endonuclease 1 | Enzyme | C00023903 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00023903 | 0 / 0 |
| P63092 | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | Other membrane protein | C00023903 | 7 / 3 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00023903 | 0 / 0 |
| Q92887 | Canalicular multispecific organic anion transporter 1 | Unclassified protein | C00023903 | 1 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00023903 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00023903 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00023903 | 1 / 4 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 8647 | ABCB11, ABC16, BRIC2, BSEP, PFIC-2, PFIC2, PGY4, SPGP | ATP-binding cassette, sub-family B (MDR/TAP), member 11 |
C00023903
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #219080 | Acth-independent macronodular adrenal hyperplasia; aimah |
P63092
|
| #237500 | Dubin-johnson syndrome; djs |
Q92887
|
| #174800 | Mccune-albright syndrome; mas |
P63092
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #166350 | Osseous heteroplasia, progressive; poh |
P63092
|
| #102200 | Pituitary adenoma, growth hormone-secreting |
P63092
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #103580 | Pseudohypoparathyroidism, type ia; php1a |
P63092
|
| #603233 | Pseudohypoparathyroidism, type ib; php1b |
P63092
|
| #612462 | Pseudohypoparathyroidism, type ic; php1c |
P63092
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00244 | Pseudohypoparathyroidism |
P63092
(related)
|
| H00441 | Progressive osseous heteroplasia (POH) |
P63092
(related)
|
| H00501 | Fibrous dysplasia, polyostotic |
P63092
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00208 | Hyperbilirubinemia |
Q92887
(related)
|
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D058186 | Acute Kidney Injury |
C00023903
|
| D000756 | Anemia, Sideroblastic |
C00023903
|
| D002779 | Cholestasis |
C00023903
|
| D003424 | Crohn Disease |
C00023903
|
| D004697 | Endocarditis, Bacterial |
C00023903
|
| D006932 | Hyperbilirubinemia |
C00023903
|
| D006996 | Hypocalcemia |
C00023903
|
| D007565 | Jaundice |
C00023903
|
| D009325 | Nausea |
C00023903
|
| D010019 | Osteomyelitis |
C00023903
|
| D012206 | Rhabdomyolysis |
C00023903
|
| D013203 | Staphylococcal Infections |
C00023903
|
| D013924 | Thrombophlebitis |
C00023903
|
| D014552 | Urinary Tract Infections |
C00023903
|