| class name | count |
|---|---|
| rosids | 5 |
| asterids | 2 |
| eudicotyledons | 1 |
| Liliopsida | 1 |
| class name | count |
|---|---|
| Fabaceae | 5 |
| Pedaliaceae | 1 |
| Montiaceae | 1 |
| Poaceae | 1 |
| Solanaceae | 1 |
| br08003 Category | # of metabolite |
|---|---|
| Amines | 1 |
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|---|---|
| Amines | C00179 | C00001400 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00001400
|
Agmatine
|
CHEMBL58343
|
D000376
|
11 / 2 / 3 | 0 / 9 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00001400 | 1 / 0 |
| O15244 | Solute carrier family 22 member 2 | Drug uniporter | C00001400 | 0 / 0 |
| O15245 | Solute carrier family 22 member 1 | Drug uniporter | C00001400 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00001400 | 0 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00001400 | 0 / 0 |
| P19838 | Nuclear factor NF-kappa-B p105 subunit | Transcription Factor | C00001400 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00001400 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00001400 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00001400 | 0 / 1 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00001400 | 0 / 0 |
| O75751 | Solute carrier family 22 member 3 | Unclassified protein | C00001400 | 0 / 0 |
| MESH or OMIM | name |
KNApSAcK
metabolite |
|---|---|---|
| D001919 | Bradycardia |
C00001400
|
| D006930 | Hyperalgesia |
C00001400
|
| D006973 | Hypertension |
C00001400
|
| D007022 | Hypotension |
C00001400
|
| D009021 | Morphine Dependence |
C00001400
|
| D009293 | Opioid-Related Disorders |
C00001400
|
| D010146 | Pain |
C00001400
|
| D013375 | Substance Withdrawal Syndrome |
C00001400
|
| D013610 | Tachycardia |
C00001400
|