Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Streptomycetaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00018019 External link 512 Coxistac
/ Salinomycin
/ Antibiotic 61477
CHEMBL1208572
CHEMBL1619796
CHEMBL2135651
C010327
89 / 36 / 31 170 / 6

Human Protein / Gene in interactions

89 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018019 1 / 0
P21728 D(1A) dopamine receptor Dopamine receptor C00018019 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00018019 0 / 3
Q12809 Potassium voltage-gated channel subfamily H member 2 KCNH, Kv10-12.x (Ether-a-go-go) C00018019 2 / 2
P08246 Neutrophil elastase S1A C00018019 2 / 1
P33765 Adenosine receptor A3 Adenosine receptor C00018019 0 / 0
Q16539 Mitogen-activated protein kinase 14 p38 C00018019 0 / 0
P49146 Neuropeptide Y receptor type 2 Neuropeptide Y receptor C00018019 0 / 0
P29466 Caspase-1 C14 C00018019 0 / 0
P17252 Protein kinase C alpha type Alpha C00018019 0 / 0
P27361 Mitogen-activated protein kinase 3 Erk C00018019 0 / 0
P14780 Matrix metalloproteinase-9 M10A C00018019 2 / 2
P00918 Carbonic anhydrase 2 Lyase C00018019 1 / 2
P07550 Beta-2 adrenergic receptor Adrenergic receptor C00018019 0 / 1
P21397 Amine oxidase [flavin-containing] A Oxidoreductase C00018019 1 / 1
P25021 Histamine H2 receptor Histamine receptor C00018019 0 / 0
P35367 Histamine H1 receptor Histamine receptor C00018019 0 / 0
Q01959 Sodium-dependent dopamine transporter Dopamine C00018019 1 / 0
P08912 Muscarinic acetylcholine receptor M5 Acetylcholine receptor C00018019 0 / 0
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00018019 0 / 0
P13945 Beta-3 adrenergic receptor Adrenergic receptor C00018019 0 / 0
P25024 C-X-C chemokine receptor type 1 CXC chemokine receptor C00018019 0 / 0
P06241 Tyrosine-protein kinase Fyn Src C00018019 0 / 0
Q08209 Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform Ser_Thr C00018019 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018019 0 / 1
P00533 Epidermal growth factor receptor TK tyrosine-protein kinase EGFR subfamily C00018019 1 / 8
P14416 D(2) dopamine receptor Dopamine receptor C00018019 2 / 0
P23219 Prostaglandin G/H synthase 1 Oxidoreductase C00018019 0 / 0
P37288 Vasopressin V1a receptor Vasopressin and oxytocin receptor C00018019 0 / 0
P41145 Kappa-type opioid receptor Opioid receptor C00018019 0 / 0
Q9Y271 Cysteinyl leukotriene receptor 1 Leukotriene receptor C00018019 0 / 0
P29274 Adenosine receptor A2a Adenosine receptor C00018019 0 / 0
P25929 Neuropeptide Y receptor type 1 Neuropeptide Y receptor C00018019 0 / 0
P50052 Type-2 angiotensin II receptor Angiotensin receptor C00018019 1 / 1
P17948 Vascular endothelial growth factor receptor 1 Vegfr C00018019 0 / 0
P41968 Melanocortin receptor 3 Melanocortin receptor C00018019 1 / 0
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00018019 0 / 0
P04035 3-hydroxy-3-methylglutaryl-coenzyme A reductase Oxidoreductase C00018019 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00018019 0 / 0
P21917 D(4) dopamine receptor Dopamine receptor C00018019 0 / 0
P30988 Calcitonin receptor Calcitonin receptor C00018019 0 / 0
P35462 D(3) dopamine receptor Dopamine receptor C00018019 1 / 0
P41143 Delta-type opioid receptor Opioid receptor C00018019 0 / 0
Q92731 Estrogen receptor beta NR3A2 C00018019 0 / 1
P41595 5-hydroxytryptamine receptor 2B Serotonin receptor C00018019 0 / 0
P25101 Endothelin-1 receptor Endothelin receptor C00018019 0 / 0
P30411 B2 bradykinin receptor Bradykinin receptor C00018019 0 / 0
P32245 Melanocortin receptor 4 Melanocortin receptor C00018019 1 / 0
P32238 Cholecystokinin receptor type A Cholecystokinin receptor C00018019 0 / 0
P08311 Cathepsin G S1A C00018019 0 / 0
Q99720 Sigma non-opioid intracellular receptor 1 Membrane receptor C00018019 1 / 0
P03956 Interstitial collagenase M10A C00018019 0 / 1
P32241 Vasoactive intestinal polypeptide receptor 1 Vasoactive intestinal peptide receptor C00018019 0 / 0
P04150 Glucocorticoid receptor NR3C1 C00018019 0 / 1
P08172 Muscarinic acetylcholine receptor M2 Acetylcholine receptor C00018019 2 / 0
P11229 Muscarinic acetylcholine receptor M1 Acetylcholine receptor C00018019 0 / 0
P21554 Cannabinoid receptor 1 Cannabinoid receptor C00018019 0 / 0
P31645 Sodium-dependent serotonin transporter Serotonin C00018019 2 / 0
P04626 Receptor tyrosine-protein kinase erbB-2 TK tyrosine-protein kinase EGFR subfamily C00018019 5 / 9
P20309 Muscarinic acetylcholine receptor M3 Acetylcholine receptor C00018019 1 / 0
P21452 Substance-K receptor Neurokinin receptor C00018019 0 / 0
P51679 C-C chemokine receptor type 4 CC chemokine receptor C00018019 0 / 0
P51681 C-C chemokine receptor type 5 CC chemokine receptor C00018019 3 / 0
P50406 5-hydroxytryptamine receptor 6 Serotonin receptor C00018019 0 / 0
P41597 C-C chemokine receptor type 2 CC chemokine receptor C00018019 1 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00018019 0 / 0
P08575 Receptor-type tyrosine-protein phosphatase C Enzyme C00018019 2 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018019 0 / 0
O76074 cGMP-specific 3',5'-cyclic phosphodiesterase PDE_5A C00018019 0 / 0
P03372 Estrogen receptor NR3A1 C00018019 1 / 1
P08588 Beta-1 adrenergic receptor Adrenergic receptor C00018019 1 / 0
P22303 Acetylcholinesterase Hydrolase C00018019 1 / 0
P28223 5-hydroxytryptamine receptor 2A Serotonin receptor C00018019 0 / 0
P28335 5-hydroxytryptamine receptor 2C Serotonin receptor C00018019 0 / 0
P35372 Mu-type opioid receptor Opioid receptor C00018019 0 / 0
P08173 Muscarinic acetylcholine receptor M4 Acetylcholine receptor C00018019 0 / 0
P25103 Substance-P receptor Neurokinin receptor C00018019 0 / 0
P25105 Platelet-activating factor receptor PAF receptor C00018019 0 / 0
P33032 Melanocortin receptor 5 Melanocortin receptor C00018019 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018019 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018019 0 / 1
P05181 Cytochrome P450 2E1 Cytochrome P450 2E1 C00018019 0 / 0
P23975 Sodium-dependent noradrenaline transporter Norepinephrine C00018019 1 / 1
P25100 Alpha-1D adrenergic receptor Adrenergic receptor C00018019 0 / 0
P30542 Adenosine receptor A1 Adenosine receptor C00018019 0 / 0
P18089 Alpha-2B adrenergic receptor Adrenergic receptor C00018019 0 / 0
P24557 Thromboxane-A synthase Cytochrome P450 5A1 C00018019 1 / 1
P06239 Tyrosine-protein kinase Lck Src C00018019 0 / 1
P25025 C-X-C chemokine receptor type 2 CXC chemokine receptor C00018019 0 / 0

170 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
55856 ACOT13, PNAS-27, THEM2 acyl-CoA thioesterase 13 C00018019
71 ACTG1, ACT, ACTG, BRWS2, DFNA20, DFNA26 actin, gamma 1 C00018019
8038 ADAM12, MCMP, MCMPMltna, MLTN, MLTNA ADAM metallopeptidase domain 12 C00018019
165 AEBP1, ACLP AE binding protein 1 C00018019
8540 AGPS, ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY alkylglycerone phosphate synthase (EC:2.5.1.26) C00018019
64853 AIDA, C1orf80, RP11-378J18.7 axin interactor, dorsalization associated C00018019
7965 AIMP2, JTV-1, JTV1, P38 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 C00018019
85365 ALG2, CDGIi, NET38, hALPG2 ALG2, alpha-1,3/1,6-mannosyltransferase (EC:2.4.1.132 2.4.1.257) C00018019
8846 ALKBH1, ABH, ABH1, ALKBH, alkB, hABH alkB, alkylation repair homolog 1 (E. coli) (EC:4.2.99.18 1.14.11.33) C00018019
9949 AMMECR1, AMMERC1 Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 C00018019
81573 ANKRD13C, RP4-677H15.5, dJ677H15.3 ankyrin repeat domain 13C C00018019
308 ANXA5, ANX5, ENX2, PP4, RPRGL3 annexin A5 C00018019
367 AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM androgen receptor C00018019
116985 ARAP1, CENTD2 ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 C00018019
377 ARF3 ADP-ribosylation factor 3 C00018019
10092 ARPC5, ARC16, dJ127C7.3, p16-Arc actin related protein 2/3 complex, subunit 5, 16kDa C00018019
467 ATF3 activating transcription factor 3 C00018019
471 ATIC, AICAR, AICARFT, IMPCHASE, PURH 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (EC:2.1.2.3 3.5.4.10) C00018019
79572 ATP13A3, AFURS1 ATPase type 13A3 C00018019
483 ATP1B3, ATPB-3, CD298 ATPase, Na+/K+ transporting, beta 3 polypeptide (EC:3.6.3.9) C00018019
4287 ATXN3, AT3, ATX3, JOS, MJD, MJD1, SCA3 ataxin 3 (EC:3.4.19.12) C00018019
7917 BAG6, BAG-6, BAT3, D6S52E, G3 BCL2-associated athanogene 6 C00018019
79020 C7orf25 chromosome 7 open reading frame 25 C00018019
84267 C9orf64 chromosome 9 open reading frame 64 C00018019
800 CALD1, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22 caldesmon 1 C00018019
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00018019
124808 CCDC43 coiled-coil domain containing 43 C00018019
6347 CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF chemokine (C-C motif) ligand 2 C00018019
894 CCND2, KIAK0002 cyclin D2 C00018019
219771 CCNY, C10orf9, CBCP1, CCNX, CFP1 cyclin Y C00018019
8872 CDC123, C10orf7, D123 cell division cycle 123 C00018019
9857 CEP350, CAP350, GM133 centrosomal protein 350kDa C00018019
6320 CLEC11A, CLECSF3, LSLCL, P47, SCGF C-type lectin domain family 11, member A C00018019
1192 CLIC1, G6, NCC27 chloride intracellular channel 1 C00018019
1213 CLTC, CHC, CHC17, CLH-17, CLTCL2, Hc clathrin, heavy chain (Hc) C00018019
29097 CNIH4, CNIH-4 cornichon family AMPA receptor auxiliary protein 4 C00018019
4850 CNOT4, CLONE243, NOT4, NOT4H CCR4-NOT transcription complex, subunit 4 C00018019
9276 COPB2, beta'-COP coatomer protein complex, subunit beta 2 (beta prime) C00018019
1457 CSNK2A1, CK2A1, CKII, CSNK2A3 casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1) C00018019
1477 CSTF1, CstF-50, CstFp50 cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa C00018019
1486 CTBS, CTB chitobiase, di-N-acetyl- (EC:3.2.1.-) C00018019
51163 DBR1 debranching RNA lariats 1 C00018019
10238 DCAF7, AN11, HAN11, SWAN-1, WDR68 DDB1 and CUL4 associated factor 7 C00018019
285761 DCBLD1, dJ94G16.1 discoidin, CUB and LCCL domain containing 1 C00018019
1634 DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B decorin C00018019
23142 DCUN1D4 DCN1, defective in cullin neddylation 1, domain containing 4 C00018019
1649 DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 DNA-damage-inducible transcript 3 C00018019
54541 DDIT4, Dig2, REDD-1, REDD1 DNA-damage-inducible transcript 4 C00018019
51029 DESI2, C1orf121, DESI, DESI1, DeSI-2, FAM152A, PNAS-4, PPPDE1 desumoylating isopeptidase 2 C00018019
23317 DNAJC13, RME8 DnaJ (Hsp40) homolog, subfamily C, member 13 C00018019
1788 DNMT3A, DNMT3A2, M.HsaIIIA DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37) C00018019
5977 DPF2, REQ, UBID4, ubi-d4 D4, zinc and double PHD fingers family 2 C00018019
1809 DPYSL3, CRMP-4, CRMP4, DRP-3, DRP3, LCRMP, ULIP, ULIP-1 dihydropyrimidinase-like 3 C00018019
1857 DVL3 dishevelled segment polarity protein 3 C00018019
9470 EIF4E2, 4E-LP, 4EHP, EIF4EL3, IF4e eukaryotic translation initiation factor 4E family member 2 C00018019
26610 ELP4, C11orf19, PAX6NEB, PAXNEB, dJ68P15A.1 elongator acetyltransferase complex subunit 4 C00018019
2014 EMP3, YMP epithelial membrane protein 3 C00018019
2078 ERG, erg-3, p55 v-ets avian erythroblastosis virus E26 oncogene homolog C00018019
54465 ETAA1, ETAA16 Ewing tumor-associated antigen 1 C00018019
2131 EXT1, EXT, LGCR, LGS, TRPS2, TTV exostosin glycosyltransferase 1 (EC:2.4.1.225 2.4.1.224) C00018019
57700 FAM160B1, KIAA1600, bA106M7.3 family with sequence similarity 160, member B1 C00018019
2260 FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 fibroblast growth factor receptor 1 (EC:2.7.10.1) C00018019
83856 FSD1L, CCDC10, CSDUFD1, FSD1CL, FSD1NL, MIR1 fibronectin type III and SPRY domain containing 1-like C00018019
2512 FTL, NBIA3 ferritin, light polypeptide C00018019
2534 FYN, SLK, SYN, p59-FYN FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) C00018019
2535 FZD2, Fz2, fz-2, fzE2, hFz2 frizzled family receptor 2 C00018019
2596 GAP43, B-50, PP46 growth associated protein 43 C00018019
2597 GAPDH, G3PD, GAPD glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) C00018019
2621 GAS6, AXLLG, AXSF growth arrest-specific 6 C00018019
2690 GHR, GHBP growth hormone receptor C00018019
10399 GNB2L1, Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 C00018019
10007 GNPDA1, GNP1, GNPDA, GNPI, GPI, HLN glucosamine-6-phosphate deaminase 1 (EC:3.5.99.6) C00018019
92344 GORAB, GO, NTKLBP1, SCYL1BP1 golgin, RAB6-interacting C00018019
2239 GPC4, K-glypican glypican 4 C00018019
10457 GPNMB, HGFIN, NMB glycoprotein (transmembrane) nmb C00018019
9052 GPRC5A, GPCR5A, RAI3, RAIG1 G protein-coupled receptor, family C, group 5, member A C00018019
2932 GSK3B glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) C00018019
9330 GTF3C3, TFIIIC102, TFIIICgamma, TFiiiC2-102 general transcription factor IIIC, polypeptide 3, 102kDa C00018019
3091 HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) C00018019
9653 HS2ST1, dJ604K5.2 heparan sulfate 2-O-sulfotransferase 1 (EC:2.8.2.-) C00018019
23463 ICMT, HSTE14, MST098, MSTP098, PCCMT, PCMT, PPMT isoprenylcysteine carboxyl methyltransferase (EC:2.1.1.100) C00018019
3482 IGF2R, CD222, CIMPR, M6P-R, MPR1, MPRI insulin-like growth factor 2 receptor C00018019
3487 IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4 insulin-like growth factor binding protein 4 C00018019
3490 IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF insulin-like growth factor binding protein 7 C00018019
57508 INTS2, INT2, KIAA1287 integrator complex subunit 2 C00018019
55656 INTS8, C8orf52, INT8 integrator complex subunit 8 C00018019
10379 IRF9, IRF-9, ISGF3, ISGF3G, p48 interferon regulatory factor 9 C00018019
11014 KDELR2, ELP-1, ERD2.2 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 C00018019
11015 KDELR3, ERD2L3 KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 C00018019
1316 KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9 Kruppel-like factor 6 C00018019
27252 KLHL20, KHLHX, KLEIP, KLHLX, RP3-383J4.3 kelch-like family member 20 C00018019
354 KLK3, APS, KLK2A1, PSA, hK3 kallikrein-related peptidase 3 (EC:3.4.21.77) C00018019
23367 LARP1, LARP La ribonucleoprotein domain family, member 1 C00018019
3939 LDHA, GSD11, LDH1, LDHM lactate dehydrogenase A (EC:1.1.1.27) C00018019
257103 C00018019
64327 LMBR1, ACHP, C7orf2, DIF14, PPD2, TPT, ZRS limb development membrane protein 1 C00018019
9663 LPIN2 lipin 2 (EC:3.1.3.4) C00018019
1432 MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA mitogen-activated protein kinase 14 (EC:2.7.11.24) C00018019
4141 MARS, METRS, MRS, MTRNS methionyl-tRNA synthetase (EC:6.1.1.10) C00018019
4319 MMP10, SL-2, STMY2 matrix metallopeptidase 10 (stromelysin 2) (EC:3.4.24.22) C00018019
4323 MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) C00018019
4494 MT1F, MT1 metallothionein 1F C00018019
4495 MT1G, MT1, MT1K metallothionein 1G C00018019
4502 MT2A, MT2 metallothionein 2A C00018019
4609 MYC, MRTL, MYCC, bHLHe39, c-Myc v-myc avian myelocytomatosis viral oncogene homolog C00018019
4651 MYO10 myosin X C00018019
55226 NAT10, ALP, NET43 N-acetyltransferase 10 (GCN5-related) (EC:2.3.1.-) C00018019
4811 NID1, NID nidogen 1 C00018019
22795 NID2, NID-2 nidogen 2 (osteonidogen) C00018019
55035 NOL8, C9orf34, NOP132, bA62C3.3, bA62C3.4 nucleolar protein 8 C00018019
4854 NOTCH3, CADASIL, CASIL, IMF2 notch 3 C00018019
4905 NSF, SKD2 N-ethylmaleimide-sensitive factor (EC:3.6.4.6) C00018019
81788 NUAK2, SNARK NUAK family, SNF1-like kinase, 2 (EC:2.7.11.1) C00018019
64710 NUCKS1, NUCKS nuclear casein kinase and cyclin-dependent kinase substrate 1 C00018019
11164 NUDT5, YSA1, YSA1H, YSAH1, hYSAH1 nudix (nucleoside diphosphate linked moiety X)-type motif 5 (EC:3.6.1.13 3.6.1.58) C00018019
79023 NUP37, p37 nucleoporin 37kDa C00018019
23636 NUP62, IBSN, SNDI, p62 nucleoporin 62kDa C00018019
5062 PAK2, PAK65, PAKgamma p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1) C00018019
5151 PDE8A, HsT19550 phosphodiesterase 8A (EC:3.1.4.17) C00018019
5159 PDGFRB, CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1 platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1) C00018019
5209 PFKFB3, IPFK2, PFK2 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46) C00018019
5230 PGK1, MIG10, PGKA phosphoglycerate kinase 1 (EC:2.7.2.3) C00018019
5311 PKD2, APKD2, PC2, PKD4, Pc-2, TRPP2 polycystic kidney disease 2 (autosomal dominant) C00018019
9373 PLAA, DOA1, PLA2P, PLAP phospholipase A2-activating protein C00018019
5352 PLOD2, LH2, TLH procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (EC:1.14.11.4) C00018019
5355 PLP2, A4, A4LSB proteolipid protein 2 (colonic epithelium-enriched) C00018019
25953 PNKD, BRP17, DYT8, FPD1, KIPP1184, MR-1, MR1, PDC, PKND1, TAHCCP2 paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) C00018019
9581 PREPL prolyl endopeptidase-like (EC:3.4.21.-) C00018019
5686 PSMA5, PSC5, ZETA proteasome (prosome, macropain) subunit, alpha type, 5 (EC:3.4.25.1) C00018019
5695 PSMB7, Z proteasome (prosome, macropain) subunit, beta type, 7 (EC:3.4.25.1) C00018019
5714 PSMD8, HIP6, HYPF, Nin1p, Rpn12, S14, p31 proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 C00018019
53635 PTOV1, ACID2, PTOV-1 prostate tumor overexpressed 1 C00018019
51715 RAB23, HSPC137 RAB23, member RAS oncogene family C00018019
5887 RAD23B, HHR23B, HR23B, P58 RAD23 homolog B (S. cerevisiae) C00018019
54453 RIN2, MACS, RASSF4 Ras and Rab interactor 2 C00018019
9025 RNF8, hRNF8 ring finger protein 8, E3 ubiquitin protein ligase (EC:6.3.2.-) C00018019
23429 RYBP, AAP1, DEDAF, YEAF1 RING1 and YY1 binding protein C00018019
79005 SCNM1 sodium channel modifier 1 C00018019
51150 SDF4, Cab45, SDF-4 stromal cell derived factor 4 C00018019
65260 SELRC1, C1orf163 Sel1 repeat containing 1 C00018019
55209 SETD5 SET domain containing 5 C00018019
23517 SKIV2L2, Dob1, KIAA0052, Mtr4, fSAP118 superkiller viralicidic activity 2-like 2 (S. cerevisiae) (EC:3.6.4.13) C00018019
153129 SLC38A9 solute carrier family 38, member 9 C00018019
55181 SMG8, C17orf71 SMG8 nonsense mediated mRNA decay factor C00018019
79622 SNRNP25, C16orf33 small nuclear ribonucleoprotein 25kDa (U11/U12) C00018019
58533 SNX6, MSTP010, TFAF2 sorting nexin 6 C00018019
26010 SPATS2L, DNAPTP6, SGNP spermatogenesis associated, serine-rich 2-like C00018019
6696 SPP1, BNSP, BSPI, ETA-1, OPN secreted phosphoprotein 1 C00018019
6729 SRP54 signal recognition particle 54kDa C00018019
6745 SSR1, TRAPA signal sequence receptor, alpha C00018019
8027 STAM, STAM-1, STAM1 signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 C00018019
6780 STAU1, STAU staufen double-stranded RNA binding protein 1 C00018019
27347 STK39, DCHT, PASK, SPAK serine threonine kinase 39 (EC:2.7.11.1) C00018019
25917 THUMPD3 THUMP domain containing 3 C00018019
353376 TICAM2, MyD88-4, TICAM-2, TIRAP3, TIRP, TRAM toll-like receptor adaptor molecule 2 C00018019
7078 TIMP3, HSMRK222, K222, K222TA2, SFD TIMP metallopeptidase inhibitor 3 C00018019
3371 TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C tenascin C C00018019
203068 TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5 tubulin, beta class I C00018019
10381 TUBB3, CDCBM, CDCBM1, CFEOM3A, TUBB4, beta-4 tubulin, beta 3 class III C00018019
129450 TYW5, C2orf60, hTYW5 tRNA-yW synthesizing protein 5 C00018019
140739 UBE2F, NCE2 ubiquitin-conjugating enzyme E2F (putative) C00018019
27338 UBE2S, E2-EPF, E2EPF, EPF5 ubiquitin-conjugating enzyme E2S (EC:6.3.2.19) C00018019
54887 UHRF1BP1, C6orf107, ICBP90, dJ349A12.1 UHRF1 binding protein 1 C00018019
81552 VOPP1, ECOP, GASP vesicular, overexpressed in cancer, prosurvival protein 1 C00018019
7456 WIPF1, PRPL-2, WASPIP, WIP WAS/WASL interacting protein family, member 1 C00018019
7511 XPNPEP1, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1 X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (EC:3.4.11.9) C00018019
9213 XPR1, SYG1, X3 xenotropic and polytropic retrovirus receptor 1 C00018019
57002 YAE1D1, C7orf36 Yae1 domain containing 1 C00018019
64393 ZMAT3, PAG608, WIG-1, WIG1 zinc finger, matrin-type 3 C00018019
79699 ZYG11B, ZYG11 zyg-11 family member B, cell cycle regulator C00018019

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (36)

OMIM preferred title UniProt
#100100 Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism P20309
#103780 Alcohol dependence P08172
P14416
P31645
#614373 Amyotrophic lateral sclerosis 16, juvenile; als16 Q99720
#602025 Body mass index quantitative trait locus 9; bmiq9 P41968
#300615 Brunner syndrome P21397
#162800 Cyclic neutropenia P08246
#612522 Diabetes mellitus, insulin-dependent, 22; iddm22 P51681
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#613659 Gastric cancer P04626
#137215 Gastric cancer, hereditary diffuse; hdgc P04626
#231095 Ghosal hematodiaphyseal dysplasia; ghdd P24557
#137800 Glioma susceptibility 1; glm1 P04626
#609423 Human immunodeficiency virus type 1, susceptibility to P41597
P51681
#603932 Intervertebral disc disease; idd P14780
#613688 Long qt syndrome 2; lqt2 Q12809
#211980 Lung cancer P00533
P04626
#608516 Major depressive disorder; mdd P08172
%300852 Mental retardation, x-linked 88; mrx88 P50052
#613073 Metaphyseal anadysplasia 2; mandp2 P14780
#126200 Multiple sclerosis, susceptibility to; ms P08575
#159900 Myoclonic dystonia P14416
#202700 Neutropenia, severe congenital, 1, autosomal dominant; scn1 P08246
#601665 Obesity P32245
#164230 Obsessive-compulsive disorder; ocd P31645
#604715 Orthostatic intolerance P23975
#259730 Osteopetrosis, autosomal recessive 3; optb3 P00918
#167000 Ovarian cancer P04626
#613135 Parkinsonism-dystonia, infantile; pkdys Q01959
#607276 Resting heart rate, variation in P08588
#608971 Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive P08575
#609620 Short qt syndrome 1; sqt1 Q12809
#190300 Tremor, hereditary essential, 1; etm1 P35462
#610379 West nile virus, susceptibility to P51681
#112100 Yt blood group antigen P22303

KEGG DISEASE (31)

KEGG name UniProt
H00016 Oral cancer P00533 (related)
P00533 (marker)
H00017 Esophageal cancer P00533 (related)
P35354 (related)
H00018 Gastric cancer P00533 (related)
P04626 (related)
H00022 Bladder cancer P00533 (related)
P04626 (related)
H00028 Choriocarcinoma P00533 (related)
P03956 (related)
P04626 (related)
H00030 Cervical cancer P00533 (related)
P04626 (related)
H00042 Glioma P00533 (related)
P00533 (marker)
H00055 Laryngeal cancer P00533 (related)
P00533 (marker)
H00241 Combined proximal and distal renal tubular acidosis (RTA type 3) P00918 (related)
H00436 Osteopetrosis P00918 (related)
H00026 Endometrial Cancer P03372 (marker)
P04626 (related)
Q92731 (marker)
H00599 46,XX disorders of sex development (Disorders related to androgen excess) P04150 (related)
H00019 Pancreatic cancer P04626 (related)
H00027 Ovarian cancer P04626 (related)
H00031 Breast cancer P04626 (related)
P04626 (marker)
H00046 Cholangiocarcinoma P04626 (related)
P35354 (related)
H00093 Combined immunodeficiencies (CIDs) P06239 (related)
H00079 Asthma P07550 (related)
H00100 Neutropenic disorders P08246 (related)
H00091 T-B+Severe combined immunodeficiencies (SCIDs) P08575 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H00025 Penile cancer P14780 (related)
P35354 (related)
H00479 Metaphyseal dysplasias P14780 (related)
H00548 Brunner syndrome P21397 (related)
H01031 Orthostatic intolerance (OI) P23975 (related)
H00490 Diaphyseal dysplasia with anemia (Ghosal) P24557 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00480 Non-syndromic X-linked mental retardation P50052 (related)
H00720 Long QT syndrome Q12809 (related)
H00725 Short QT syndrome Q12809 (related)

Diseases related to CTD interactions

6 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001943 Breast Neoplasms C00018019
D007938 Leukemia C00018019
D008325 Mammary Neoplasms, Experimental C00018019
D009361 Neoplasm Invasiveness C00018019
D011471 Prostatic Neoplasms C00018019
D002583 Uterine Cervical Neoplasms C00018019