KNApSAcK Metabolite C00018019
Metabolite
KNApSAcK Entry
| id | C00018019 |
|---|---|
| Name | Coxistac / Salinomycin / Antibiotic 61477 |
| CAS RN | 53003-10-4 |
| Standard InChI | InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47)/t23-,24-,25+,26-,27-,28-,29+,30-,31+,32+,33+,34+,36+,37-,39-,40+,41-,42-/m0/s1 |
| Standard InChI (Main Layer) | InChI=1S/C42H70O11/c1-11-29(38(46)47)31-15-14-23(4)36(50-31)27(8)34(44)26(7)35(45)30(12-2)37-24(5)22-25(6)41(51-37)19-16-32(43)42(53-41)21-20-39(10,52-42)33-17-18-40(48,13-3)28(9)49-33/h16,19,23-34,36-37,43-44,48H,11-15,17-18,20-22H2,1-10H3,(H,46,47) |
Cluster
| Phytochemical cluster | |
|---|---|
| KCF-S cluster | No. 7454 |
Link
ChEMBL
| By standard InChI | CHEMBL1208572 |
|---|---|
| By standard InChI Main Layer | CHEMBL1208572 CHEMBL1619796 CHEMBL2135651 |
KEGG
| By LinkDB | C15690 |
|---|
CTD
| By CAS RN | C010327 |
|---|
Species
Summary
Plant class
| class name | count |
|---|
Family
| family name | count |
|---|---|
| Streptomycetaceae | 1 |
List (1)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Streptomyces albus ATCC 21838 | 1883 | Streptomycetaceae | Bacteria |
Human Protein / Gene in interaction
89 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | CHEMBL1208572 |
CHEMBL1909136
(2)
|
1 / 0 |
| P21728 | D(1A) dopamine receptor | Dopamine receptor | CHEMBL1208572 |
CHEMBL1909139
(2)
|
0 / 0 |
| P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | CHEMBL1208572 |
CHEMBL1909131
(2)
|
0 / 3 |
| Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | CHEMBL1208572 |
CHEMBL1909190
(2)
|
2 / 2 |
| P08246 | Neutrophil elastase | S1A | CHEMBL1208572 |
CHEMBL1909195
(2)
|
2 / 1 |
| P33765 | Adenosine receptor A3 | Adenosine receptor | CHEMBL1208572 |
CHEMBL1909215
(2)
|
0 / 0 |
| Q16539 | Mitogen-activated protein kinase 14 | p38 | CHEMBL1208572 |
CHEMBL1909201
(2)
|
0 / 0 |
| P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | CHEMBL1208572 |
CHEMBL1909176
(2)
|
0 / 0 |
| P29466 | Caspase-1 | C14 | CHEMBL1208572 |
CHEMBL1909193
(2)
|
0 / 0 |
| P17252 | Protein kinase C alpha type | Alpha | CHEMBL1208572 |
CHEMBL1909198
(2)
|
0 / 0 |
| P27361 | Mitogen-activated protein kinase 3 | Erk | CHEMBL1208572 |
CHEMBL1909199
(2)
|
0 / 0 |
| P14780 | Matrix metalloproteinase-9 | M10A | CHEMBL1208572 |
CHEMBL1909197
(2)
|
2 / 2 |
| P00918 | Carbonic anhydrase 2 | Lyase | CHEMBL1208572 |
CHEMBL1909123
(2)
|
1 / 2 |
| P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909092
(2)
|
0 / 1 |
| P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | CHEMBL1208572 |
CHEMBL1909169
(2)
|
1 / 1 |
| P25021 | Histamine H2 receptor | Histamine receptor | CHEMBL1208572 |
CHEMBL1909157
(2)
|
0 / 0 |
| P35367 | Histamine H1 receptor | Histamine receptor | CHEMBL1208572 |
CHEMBL1909156
(2)
|
0 / 0 |
| Q01959 | Sodium-dependent dopamine transporter | Dopamine | CHEMBL1208572 |
CHEMBL1909143
(2)
|
1 / 0 |
| P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | CHEMBL1208572 |
CHEMBL1909174
(2)
|
0 / 0 |
| P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909090
(2)
|
0 / 0 |
| P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909093
(2)
|
0 / 0 |
| P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | CHEMBL1208572 |
CHEMBL1909127
(2)
|
0 / 0 |
| P06241 | Tyrosine-protein kinase Fyn | Src | CHEMBL1208572 |
CHEMBL1909204
(2)
|
0 / 0 |
| Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | CHEMBL1208572 |
CHEMBL1909202
(2)
|
0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | CHEMBL1208572 |
CHEMBL1909135
(2)
|
0 / 1 |
| P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | CHEMBL1208572 |
CHEMBL1909203
(2)
|
1 / 11 |
| P14416 | D(2) dopamine receptor | Dopamine receptor | CHEMBL1208572 |
CHEMBL1909140
(2)
|
2 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | CHEMBL1208572 |
CHEMBL1909130
(2)
|
0 / 0 |
| P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | CHEMBL1208572 |
CHEMBL1909120
(2)
|
0 / 0 |
| P41145 | Kappa-type opioid receptor | Opioid receptor | CHEMBL1208572 |
CHEMBL1909181
(2)
|
0 / 0 |
| Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | CHEMBL1208572 |
CHEMBL1909164
(2)
|
0 / 0 |
| P29274 | Adenosine receptor A2a | Adenosine receptor | CHEMBL1208572 |
CHEMBL1909214
(2)
|
0 / 0 |
| P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | CHEMBL1208572 |
CHEMBL1909175
(2)
|
0 / 0 |
| P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | CHEMBL1208572 |
CHEMBL1909096
(2)
|
1 / 1 |
| P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | CHEMBL1208572 |
CHEMBL1909118
(2)
|
0 / 0 |
| P41968 | Melanocortin receptor 3 | Melanocortin receptor | CHEMBL1208572 |
CHEMBL1909166
(2)
|
1 / 0 |
| P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | CHEMBL1208572 |
CHEMBL1909133
(2)
|
0 / 0 |
| P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | CHEMBL1208572 |
CHEMBL1909158
(2)
|
0 / 0 |
| P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909088
(2)
|
0 / 0 |
| P21917 | D(4) dopamine receptor | Dopamine receptor | CHEMBL1208572 |
CHEMBL1909142
(2)
|
0 / 0 |
| P30988 | Calcitonin receptor | Calcitonin receptor | CHEMBL1208572 |
CHEMBL1909101
(2)
|
0 / 0 |
| P35462 | D(3) dopamine receptor | Dopamine receptor | CHEMBL1208572 |
CHEMBL1909141
(2)
|
1 / 0 |
| P41143 | Delta-type opioid receptor | Opioid receptor | CHEMBL1208572 |
CHEMBL1909180
(2)
|
0 / 0 |
| Q92731 | Estrogen receptor beta | NR3A2 | CHEMBL1208572 |
CHEMBL1909146
(2)
|
0 / 1 |
| P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | CHEMBL1208572 |
CHEMBL1909104
(2)
|
0 / 0 |
| P25101 | Endothelin-1 receptor | Endothelin receptor | CHEMBL1208572 |
CHEMBL1909144
(2)
|
0 / 0 |
| P30411 | B2 bradykinin receptor | Bradykinin receptor | CHEMBL1208572 |
CHEMBL1909100
(2)
|
0 / 0 |
| P32245 | Melanocortin receptor 4 | Melanocortin receptor | CHEMBL1208572 |
CHEMBL1909167
(2)
|
1 / 0 |
| P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | CHEMBL1208572 |
CHEMBL1909129
(2)
|
0 / 0 |
| P08311 | Cathepsin G | S1A | CHEMBL1208572 |
CHEMBL1909194
(2)
|
0 / 0 |
| Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | CHEMBL1208572 |
CHEMBL1909110
(2)
|
1 / 0 |
| P03956 | Interstitial collagenase | M10A | CHEMBL1208572 |
CHEMBL1909196
(2)
|
0 / 1 |
| P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | CHEMBL1208572 |
CHEMBL1909119
(2)
|
0 / 0 |
| P04150 | Glucocorticoid receptor | NR3C1 | CHEMBL1208572 |
CHEMBL1909150
(2)
|
0 / 1 |
| P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | CHEMBL1208572 |
CHEMBL1909171
(2)
|
2 / 0 |
| P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | CHEMBL1208572 |
CHEMBL1909170
(2)
|
0 / 0 |
| P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | CHEMBL1208572 |
CHEMBL1909122
(2)
|
0 / 0 |
| P31645 | Sodium-dependent serotonin transporter | Serotonin | CHEMBL1208572 |
CHEMBL1909109
(2)
|
2 / 0 |
| P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | CHEMBL1208572 |
CHEMBL1909205
(2)
|
5 / 10 |
| P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | CHEMBL1208572 |
CHEMBL1909172
(2)
|
1 / 0 |
| P21452 | Substance-K receptor | Neurokinin receptor | CHEMBL1208572 |
CHEMBL1909114
(2)
|
0 / 0 |
| P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | CHEMBL1208572 |
CHEMBL1909125
(2)
|
0 / 0 |
| P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | CHEMBL1208572 |
CHEMBL1909126
(2)
|
3 / 0 |
| P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | CHEMBL1208572 |
CHEMBL1909108
(2)
|
0 / 0 |
| P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | CHEMBL1208572 |
CHEMBL1909124
(2)
|
1 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | CHEMBL1208572 |
CHEMBL1909200
(2)
|
0 / 0 |
| P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | CHEMBL1208572 |
CHEMBL1909207
(2)
|
2 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | CHEMBL1208572 |
CHEMBL1909132
(2)
|
0 / 0 |
| O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | CHEMBL1208572 |
CHEMBL1909186
(2)
|
0 / 0 |
| P03372 | Estrogen receptor | NR3A1 | CHEMBL1208572 |
CHEMBL1909145
(2)
|
1 / 1 |
| P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909091
(2)
|
1 / 0 |
| P22303 | Acetylcholinesterase | Hydrolase | CHEMBL1208572 |
CHEMBL1909212
(2)
|
1 / 0 |
| P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | CHEMBL1208572 |
CHEMBL1909211
(2)
|
0 / 0 |
| P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | CHEMBL1208572 |
CHEMBL1909105
(2)
|
0 / 0 |
| P35372 | Mu-type opioid receptor | Opioid receptor | CHEMBL1208572 |
CHEMBL1909182
(2)
|
0 / 0 |
| P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | CHEMBL1208572 |
CHEMBL1909173
(2)
|
0 / 0 |
| P25103 | Substance-P receptor | Neurokinin receptor | CHEMBL1208572 |
CHEMBL1909113
(2)
|
0 / 0 |
| P25105 | Platelet-activating factor receptor | PAF receptor | CHEMBL1208572 |
CHEMBL1909187
(2)
|
0 / 0 |
| P33032 | Melanocortin receptor 5 | Melanocortin receptor | CHEMBL1208572 |
CHEMBL1909168
(2)
|
0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | CHEMBL1208572 |
CHEMBL1909134
(2)
|
1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | CHEMBL1208572 |
CHEMBL1909138
(2)
|
0 / 1 |
| P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | CHEMBL1208572 |
CHEMBL1909137
(2)
|
0 / 0 |
| P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | CHEMBL1208572 |
CHEMBL1909094
(2)
|
1 / 1 |
| P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909087
(2)
|
0 / 0 |
| P30542 | Adenosine receptor A1 | Adenosine receptor | CHEMBL1208572 |
CHEMBL1909213
(2)
|
0 / 0 |
| P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | CHEMBL1208572 |
CHEMBL1909089
(2)
|
0 / 0 |
| P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | CHEMBL1208572 |
CHEMBL1909116
(2)
|
1 / 1 |
| P06239 | Tyrosine-protein kinase Lck | Src | CHEMBL1208572 |
CHEMBL1909206
(2)
|
0 / 1 |
| P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | CHEMBL1208572 |
CHEMBL1909128
(2)
|
0 / 0 |
CTD interaction (172)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C010327 | 55856 |
ACOT13
PNAS-27 THEM2 |
acyl-CoA thioesterase 13 | salinomycin results in decreased expression of ACOT13 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 71 |
ACTG1
ACT ACTG BRWS2 DFNA20 DFNA26 |
actin, gamma 1 | salinomycin results in decreased expression of ACTG1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 8038 |
ADAM12
MCMP MCMPMltna MLTN MLTNA |
ADAM metallopeptidase domain 12 | salinomycin results in decreased expression of ADAM12 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 165 |
AEBP1
ACLP |
AE binding protein 1 | salinomycin results in decreased expression of AEBP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 8540 |
AGPS
ADAP-S ADAS ADHAPS ADPS ALDHPSY |
alkylglycerone phosphate synthase (EC:2.5.1.26) | salinomycin results in decreased expression of AGPS mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 64853 |
AIDA
C1orf80 RP11-378J18.7 |
axin interactor, dorsalization associated | salinomycin results in decreased expression of AIDA mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 7965 |
AIMP2
JTV-1 JTV1 P38 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 | salinomycin results in decreased expression of AIMP2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 85365 |
ALG2
CDGIi NET38 hALPG2 |
ALG2, alpha-1,3/1,6-mannosyltransferase (EC:2.4.1.132 2.4.1.257) | salinomycin results in decreased expression of ALG2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 8846 |
ALKBH1
ABH ABH1 ALKBH alkB hABH |
alkB, alkylation repair homolog 1 (E. coli) (EC:4.2.99.18 1.14.11.33) | salinomycin results in decreased expression of ALKBH1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9949 |
AMMECR1
AMMERC1 |
Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 | salinomycin results in decreased expression of AMMECR1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 81573 |
ANKRD13C
RP4-677H15.5 dJ677H15.3 |
ankyrin repeat domain 13C | salinomycin results in decreased expression of ANKRD13C mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 308 |
ANXA5
ANX5 ENX2 PP4 RPRGL3 |
annexin A5 | salinomycin results in decreased expression of ANXA5 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | salinomycin results in decreased expression of AR mRNA |
decreases expression
|
mRNA |
22215106
|
| C010327 | 367 |
AR
AIS DHTR HUMARA HYSP1 KD NR3C4 SBMA SMAX1 TFM |
androgen receptor | salinomycin results in decreased expression of AR protein |
decreases expression
|
protein |
22215106
|
| C010327 | 116985 |
ARAP1
CENTD2 |
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 | salinomycin results in decreased expression of ARAP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 377 |
ARF3
|
ADP-ribosylation factor 3 | salinomycin results in decreased expression of ARF3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10092 |
ARPC5
ARC16 dJ127C7.3 p16-Arc |
actin related protein 2/3 complex, subunit 5, 16kDa | salinomycin results in decreased expression of ARPC5 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 467 |
ATF3
|
activating transcription factor 3 | salinomycin results in increased expression of ATF3 mRNA |
increases expression
|
mRNA |
22215106
|
| C010327 | 471 |
ATIC
AICAR AICARFT IMPCHASE PURH |
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (EC:2.1.2.3 3.5.4.10) | salinomycin results in decreased expression of ATIC mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 79572 |
ATP13A3
AFURS1 |
ATPase type 13A3 | salinomycin results in decreased expression of ATP13A3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 483 |
ATP1B3
ATPB-3 CD298 |
ATPase, Na+/K+ transporting, beta 3 polypeptide (EC:3.6.3.9) | salinomycin results in decreased expression of ATP1B3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4287 |
ATXN3
AT3 ATX3 JOS MJD MJD1 SCA3 |
ataxin 3 (EC:3.4.19.12) | salinomycin results in decreased expression of ATXN3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 7917 |
BAG6
BAG-6 BAT3 D6S52E G3 |
BCL2-associated athanogene 6 | salinomycin results in decreased expression of BAG6 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 79020 |
C7orf25
|
chromosome 7 open reading frame 25 | salinomycin results in decreased expression of C7ORF25 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 84267 |
C9orf64
|
chromosome 9 open reading frame 64 | salinomycin results in decreased expression of C9ORF64 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 800 |
CALD1
CDM H-CAD HCAD L-CAD LCAD NAG22 |
caldesmon 1 | salinomycin results in decreased expression of CALD1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 841 |
CASP8
ALPS2B CAP4 Casp-8 FLICE MACH MCH5 |
caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) | salinomycin results in decreased expression of CASP8 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 124808 |
CCDC43
|
coiled-coil domain containing 43 | salinomycin results in decreased expression of CCDC43 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 6347 |
CCL2
GDCF-2 HC11 HSMCR30 MCAF MCP-1 MCP1 SCYA2 SMC-CF |
chemokine (C-C motif) ligand 2 | salinomycin results in decreased expression of CCL2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 894 |
CCND2
KIAK0002 |
cyclin D2 | salinomycin results in decreased expression of CCND2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 219771 |
CCNY
C10orf9 CBCP1 CCNX CFP1 |
cyclin Y | salinomycin results in decreased expression of CCNY mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 8872 |
CDC123
C10orf7 D123 |
cell division cycle 123 | salinomycin results in decreased expression of CDC123 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9857 |
CEP350
CAP350 GM133 |
centrosomal protein 350kDa | salinomycin results in decreased expression of CEP350 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 6320 |
CLEC11A
CLECSF3 LSLCL P47 SCGF |
C-type lectin domain family 11, member A | salinomycin results in decreased expression of CLEC11A mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1192 |
CLIC1
G6 NCC27 |
chloride intracellular channel 1 | salinomycin results in decreased expression of CLIC1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1213 |
CLTC
CHC CHC17 CLH-17 CLTCL2 Hc |
clathrin, heavy chain (Hc) | salinomycin results in decreased expression of CLTC mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 29097 |
CNIH4
CNIH-4 |
cornichon family AMPA receptor auxiliary protein 4 | salinomycin results in decreased expression of CNIH4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4850 |
CNOT4
CLONE243 NOT4 NOT4H |
CCR4-NOT transcription complex, subunit 4 | salinomycin results in decreased expression of CNOT4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9276 |
COPB2
beta'-COP |
coatomer protein complex, subunit beta 2 (beta prime) | salinomycin results in decreased expression of COPB2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1457 |
CSNK2A1
CK2A1 CKII CSNK2A3 |
casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1) | salinomycin results in decreased expression of CSNK2A1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1477 |
CSTF1
CstF-50 CstFp50 |
cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa | salinomycin results in decreased expression of CSTF1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1486 |
CTBS
CTB |
chitobiase, di-N-acetyl- (EC:3.2.1.-) | salinomycin results in decreased expression of CTBS mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 51163 |
DBR1
|
debranching RNA lariats 1 | salinomycin results in decreased expression of DBR1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10238 |
DCAF7
AN11 HAN11 SWAN-1 WDR68 |
DDB1 and CUL4 associated factor 7 | salinomycin results in decreased expression of DCAF7 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 285761 |
DCBLD1
dJ94G16.1 |
discoidin, CUB and LCCL domain containing 1 | salinomycin results in decreased expression of DCBLD1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1634 |
DCN
CSCD DSPG2 PG40 PGII PGS2 SLRR1B |
decorin | salinomycin results in decreased expression of DCN mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 23142 |
DCUN1D4
|
DCN1, defective in cullin neddylation 1, domain containing 4 | salinomycin results in decreased expression of DCUN1D4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1649 |
DDIT3
CEBPZ CHOP CHOP-10 CHOP10 GADD153 |
DNA-damage-inducible transcript 3 | salinomycin results in increased expression of DDIT3 mRNA |
increases expression
|
mRNA |
22215106
|
| C010327 | 54541 |
DDIT4
Dig2 REDD-1 REDD1 |
DNA-damage-inducible transcript 4 | salinomycin results in increased expression of DDIT4 mRNA |
increases expression
|
mRNA |
22215106
|
| C010327 | 51029 |
DESI2
C1orf121 DESI DESI1 DeSI-2 FAM152A PNAS-4 PPPDE1 |
desumoylating isopeptidase 2 | salinomycin results in decreased expression of DESI2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 23317 |
DNAJC13
RME8 |
DnaJ (Hsp40) homolog, subfamily C, member 13 | salinomycin results in decreased expression of DNAJC13 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1788 |
DNMT3A
DNMT3A2 M.HsaIIIA |
DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37) | salinomycin results in decreased expression of DNMT3A mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5977 |
DPF2
REQ UBID4 ubi-d4 |
D4, zinc and double PHD fingers family 2 | salinomycin results in decreased expression of DPF2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1809 |
DPYSL3
CRMP-4 CRMP4 DRP-3 DRP3 LCRMP ULIP ULIP-1 |
dihydropyrimidinase-like 3 | salinomycin results in decreased expression of DPYSL3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1857 |
DVL3
|
dishevelled segment polarity protein 3 | salinomycin results in decreased expression of DVL3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9470 |
EIF4E2
4E-LP 4EHP EIF4EL3 IF4e |
eukaryotic translation initiation factor 4E family member 2 | salinomycin results in decreased expression of EIF4E2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 26610 |
ELP4
C11orf19 PAX6NEB PAXNEB dJ68P15A.1 |
elongator acetyltransferase complex subunit 4 | salinomycin results in decreased expression of ELP4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2014 |
EMP3
YMP |
epithelial membrane protein 3 | salinomycin results in decreased expression of EMP3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2078 |
ERG
erg-3 p55 |
v-ets avian erythroblastosis virus E26 oncogene homolog | salinomycin results in decreased expression of ERG mRNA |
decreases expression
|
mRNA |
22215106
|
| C010327 | 54465 |
ETAA1
ETAA16 |
Ewing tumor-associated antigen 1 | salinomycin results in decreased expression of ETAA1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2131 |
EXT1
EXT LGCR LGS TRPS2 TTV |
exostosin glycosyltransferase 1 (EC:2.4.1.225 2.4.1.224) | salinomycin results in decreased expression of EXT1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 57700 |
FAM160B1
KIAA1600 bA106M7.3 |
family with sequence similarity 160, member B1 | salinomycin results in decreased expression of FAM160B1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2260 |
FGFR1
BFGFR CD331 CEK FGFBR FGFR-1 FLG FLT-2 FLT2 HBGFR HH2 HRTFDS KAL2 N-SAM OGD bFGF-R-1 |
fibroblast growth factor receptor 1 (EC:2.7.10.1) | salinomycin results in decreased expression of FGFR1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 83856 |
FSD1L
CCDC10 CSDUFD1 FSD1CL FSD1NL MIR1 |
fibronectin type III and SPRY domain containing 1-like | salinomycin results in decreased expression of FSD1L mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2512 |
FTL
NBIA3 |
ferritin, light polypeptide | salinomycin results in decreased expression of FTL mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2534 |
FYN
SLK SYN p59-FYN |
FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) | salinomycin results in decreased expression of FYN mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2535 |
FZD2
Fz2 fz-2 fzE2 hFz2 |
frizzled family receptor 2 | salinomycin results in decreased expression of FZD2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2596 |
GAP43
B-50 PP46 |
growth associated protein 43 | salinomycin results in decreased expression of GAP43 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2597 |
GAPDH
G3PD GAPD |
glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) | salinomycin results in decreased expression of GAPDH mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2621 |
GAS6
AXLLG AXSF |
growth arrest-specific 6 | salinomycin results in decreased expression of GAS6 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2690 |
GHR
GHBP |
growth hormone receptor | salinomycin results in decreased expression of GHR mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10399 |
GNB2L1
Gnb2-rs1 H12.3 HLC-7 PIG21 RACK1 |
guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 | salinomycin results in decreased expression of GNB2L1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10007 |
GNPDA1
GNP1 GNPDA GNPI GPI HLN |
glucosamine-6-phosphate deaminase 1 (EC:3.5.99.6) | salinomycin results in decreased expression of GNPDA1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 92344 |
GORAB
GO NTKLBP1 SCYL1BP1 |
golgin, RAB6-interacting | salinomycin results in decreased expression of GORAB mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2239 |
GPC4
K-glypican |
glypican 4 | salinomycin results in decreased expression of GPC4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10457 |
GPNMB
HGFIN NMB |
glycoprotein (transmembrane) nmb | salinomycin results in decreased expression of GPNMB mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9052 |
GPRC5A
GPCR5A RAI3 RAIG1 |
G protein-coupled receptor, family C, group 5, member A | salinomycin results in decreased expression of GPRC5A mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 2932 |
GSK3B
|
glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) | salinomycin results in decreased expression of GSK3B mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9330 |
GTF3C3
TFIIIC102 TFIIICgamma TFiiiC2-102 |
general transcription factor IIIC, polypeptide 3, 102kDa | salinomycin results in decreased expression of GTF3C3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 3091 |
HIF1A
HIF-1A HIF-1alpha HIF1 HIF1-ALPHA MOP1 PASD8 bHLHe78 |
hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | salinomycin results in decreased expression of HIF1A mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9653 |
HS2ST1
dJ604K5.2 |
heparan sulfate 2-O-sulfotransferase 1 (EC:2.8.2.-) | salinomycin results in decreased expression of HS2ST1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 23463 |
ICMT
HSTE14 MST098 MSTP098 PCCMT PCMT PPMT |
isoprenylcysteine carboxyl methyltransferase (EC:2.1.1.100) | salinomycin results in decreased expression of ICMT mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 3482 |
IGF2R
CD222 CIMPR M6P-R MPR1 MPRI |
insulin-like growth factor 2 receptor | salinomycin results in decreased expression of IGF2R mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 3487 |
IGFBP4
BP-4 HT29-IGFBP IBP4 IGFBP-4 |
insulin-like growth factor binding protein 4 | salinomycin results in decreased expression of IGFBP4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 3490 |
IGFBP7
AGM FSTL2 IBP-7 IGFBP-7 IGFBP-7v IGFBPRP1 MAC25 PSF RAMSVPS TAF |
insulin-like growth factor binding protein 7 | salinomycin results in decreased expression of IGFBP7 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 57508 |
INTS2
INT2 KIAA1287 |
integrator complex subunit 2 | salinomycin results in decreased expression of INTS2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 55656 |
INTS8
C8orf52 INT8 |
integrator complex subunit 8 | salinomycin results in decreased expression of INTS8 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10379 |
IRF9
IRF-9 ISGF3 ISGF3G p48 |
interferon regulatory factor 9 | salinomycin results in decreased expression of IRF9 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 11014 |
KDELR2
ELP-1 ERD2.2 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | salinomycin results in decreased expression of KDELR2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 11015 |
KDELR3
ERD2L3 |
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 | salinomycin results in decreased expression of KDELR3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1316 |
KLF6
BCD1 CBA1 COPEB CPBP GBF PAC1 ST12 ZF9 |
Kruppel-like factor 6 | salinomycin results in increased expression of KLF6 mRNA |
increases expression
|
mRNA |
22215106
|
| C010327 | 27252 |
KLHL20
KHLHX KLEIP KLHLX RP3-383J4.3 |
kelch-like family member 20 | salinomycin results in decreased expression of KLHL20 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 354 |
KLK3
APS KLK2A1 PSA hK3 |
kallikrein-related peptidase 3 (EC:3.4.21.77) | salinomycin results in decreased expression of KLK3 mRNA |
decreases expression
|
mRNA |
22215106
|
| C010327 | 354 |
KLK3
APS KLK2A1 PSA hK3 |
kallikrein-related peptidase 3 (EC:3.4.21.77) | salinomycin results in decreased expression of KLK3 protein |
decreases expression
|
protein |
22215106
|
| C010327 | 23367 |
LARP1
LARP |
La ribonucleoprotein domain family, member 1 | salinomycin results in decreased expression of LARP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 3939 |
LDHA
GSD11 LDH1 LDHM |
lactate dehydrogenase A (EC:1.1.1.27) | salinomycin results in decreased expression of LDHA mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 257103 | salinomycin results in decreased expression of LINC00205 mRNA |
decreases expression
|
mRNA |
19682730
|
||
| C010327 | 64327 |
LMBR1
ACHP C7orf2 DIF14 PPD2 TPT ZRS |
limb development membrane protein 1 | salinomycin results in decreased expression of LMBR1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9663 |
LPIN2
|
lipin 2 (EC:3.1.3.4) | salinomycin results in decreased expression of LPIN2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 1432 |
MAPK14
CSBP CSBP1 CSBP2 CSPB1 EXIP Mxi2 PRKM14 PRKM15 RK SAPK2A p38 p38ALPHA |
mitogen-activated protein kinase 14 (EC:2.7.11.24) | salinomycin results in decreased expression of MAPK14 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4141 |
MARS
METRS MRS MTRNS |
methionyl-tRNA synthetase (EC:6.1.1.10) | salinomycin results in decreased expression of MARS mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4319 |
MMP10
SL-2 STMY2 |
matrix metallopeptidase 10 (stromelysin 2) (EC:3.4.24.22) | salinomycin results in decreased expression of MMP10 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4323 |
MMP14
MMP-14 MMP-X1 MT-MMP MT-MMP_1 MT1-MMP MT1MMP MTMMP1 WNCHRS |
matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) | salinomycin results in decreased expression of MMP14 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4494 |
MT1F
MT1 |
metallothionein 1F | salinomycin results in increased expression of MT1F mRNA |
increases expression
|
mRNA |
22215106
|
| C010327 | 4495 |
MT1G
MT1 MT1K |
metallothionein 1G | salinomycin results in increased expression of MT1G mRNA |
increases expression
|
mRNA |
22215106
|
| C010327 | 4502 |
MT2A
MT2 |
metallothionein 2A | salinomycin results in decreased expression of MT2A mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4609 |
MYC
MRTL MYCC bHLHe39 c-Myc |
v-myc avian myelocytomatosis viral oncogene homolog | salinomycin results in decreased expression of MYC mRNA |
decreases expression
|
mRNA |
22215106
|
| C010327 | 4651 |
MYO10
|
myosin X | salinomycin results in decreased expression of MYO10 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 55226 |
NAT10
ALP NET43 |
N-acetyltransferase 10 (GCN5-related) (EC:2.3.1.-) | salinomycin results in decreased expression of NAT10 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4811 |
NID1
NID |
nidogen 1 | salinomycin results in decreased expression of NID1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 22795 |
NID2
NID-2 |
nidogen 2 (osteonidogen) | salinomycin results in decreased expression of NID2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 55035 |
NOL8
C9orf34 NOP132 bA62C3.3 bA62C3.4 |
nucleolar protein 8 | salinomycin results in decreased expression of NOL8 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4854 |
NOTCH3
CADASIL CASIL IMF2 |
notch 3 | salinomycin results in decreased expression of NOTCH3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 4905 |
NSF
SKD2 |
N-ethylmaleimide-sensitive factor (EC:3.6.4.6) | salinomycin results in decreased expression of NSF mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 81788 |
NUAK2
SNARK |
NUAK family, SNF1-like kinase, 2 (EC:2.7.11.1) | salinomycin results in decreased expression of NUAK2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 64710 |
NUCKS1
NUCKS |
nuclear casein kinase and cyclin-dependent kinase substrate 1 | salinomycin results in decreased expression of NUCKS1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 11164 |
NUDT5
YSA1 YSA1H YSAH1 hYSAH1 |
nudix (nucleoside diphosphate linked moiety X)-type motif 5 (EC:3.6.1.13 3.6.1.58) | salinomycin results in decreased expression of NUDT5 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 79023 |
NUP37
p37 |
nucleoporin 37kDa | salinomycin results in decreased expression of NUP37 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 23636 |
NUP62
IBSN SNDI p62 |
nucleoporin 62kDa | salinomycin results in decreased expression of NUP62 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5062 |
PAK2
PAK65 PAKgamma |
p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1) | salinomycin results in decreased expression of PAK2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5151 |
PDE8A
HsT19550 |
phosphodiesterase 8A (EC:3.1.4.17) | salinomycin results in decreased expression of PDE8A mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5159 |
PDGFRB
CD140B IBGC4 IMF1 JTK12 PDGFR PDGFR-1 PDGFR1 |
platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1) | salinomycin results in decreased expression of PDGFRB mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5209 |
PFKFB3
IPFK2 PFK2 |
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46) | salinomycin results in decreased expression of PFKFB3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5230 |
PGK1
MIG10 PGKA |
phosphoglycerate kinase 1 (EC:2.7.2.3) | salinomycin results in decreased expression of PGK1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5311 |
PKD2
APKD2 PC2 PKD4 Pc-2 TRPP2 |
polycystic kidney disease 2 (autosomal dominant) | salinomycin results in decreased expression of PKD2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9373 |
PLAA
DOA1 PLA2P PLAP |
phospholipase A2-activating protein | salinomycin results in decreased expression of PLAA mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5352 |
PLOD2
LH2 TLH |
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (EC:1.14.11.4) | salinomycin results in decreased expression of PLOD2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5355 |
PLP2
A4 A4LSB |
proteolipid protein 2 (colonic epithelium-enriched) | salinomycin results in decreased expression of PLP2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 25953 |
PNKD
BRP17 DYT8 FPD1 KIPP1184 MR-1 MR1 PDC PKND1 TAHCCP2 |
paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) | salinomycin results in decreased expression of PNKD mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9581 |
PREPL
|
prolyl endopeptidase-like (EC:3.4.21.-) | salinomycin results in decreased expression of PREPL mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5686 |
PSMA5
PSC5 ZETA |
proteasome (prosome, macropain) subunit, alpha type, 5 (EC:3.4.25.1) | salinomycin results in decreased expression of PSMA5 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5695 |
PSMB7
Z |
proteasome (prosome, macropain) subunit, beta type, 7 (EC:3.4.25.1) | salinomycin results in decreased expression of PSMB7 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5714 |
PSMD8
HIP6 HYPF Nin1p Rpn12 S14 p31 |
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 | salinomycin results in decreased expression of PSMD8 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 53635 |
PTOV1
ACID2 PTOV-1 |
prostate tumor overexpressed 1 | salinomycin results in decreased expression of PTOV1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 51715 |
RAB23
HSPC137 |
RAB23, member RAS oncogene family | salinomycin results in decreased expression of RAB23 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 5887 |
RAD23B
HHR23B HR23B P58 |
RAD23 homolog B (S. cerevisiae) | salinomycin results in decreased expression of RAD23B mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 54453 |
RIN2
MACS RASSF4 |
Ras and Rab interactor 2 | salinomycin results in decreased expression of RIN2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9025 |
RNF8
hRNF8 |
ring finger protein 8, E3 ubiquitin protein ligase (EC:6.3.2.-) | salinomycin results in decreased expression of RNF8 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 23429 |
RYBP
AAP1 DEDAF YEAF1 |
RING1 and YY1 binding protein | salinomycin results in decreased expression of RYBP mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 79005 |
SCNM1
|
sodium channel modifier 1 | salinomycin results in decreased expression of SCNM1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 51150 |
SDF4
Cab45 SDF-4 |
stromal cell derived factor 4 | salinomycin results in decreased expression of SDF4 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 65260 |
SELRC1
C1orf163 |
Sel1 repeat containing 1 | salinomycin results in decreased expression of SELRC1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 55209 |
SETD5
|
SET domain containing 5 | salinomycin results in decreased expression of SETD5 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 23517 |
SKIV2L2
Dob1 KIAA0052 Mtr4 fSAP118 |
superkiller viralicidic activity 2-like 2 (S. cerevisiae) (EC:3.6.4.13) | salinomycin results in decreased expression of SKIV2L2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 153129 |
SLC38A9
|
solute carrier family 38, member 9 | salinomycin results in decreased expression of SLC38A9 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 55181 |
SMG8
C17orf71 |
SMG8 nonsense mediated mRNA decay factor | salinomycin results in decreased expression of SMG8 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 79622 |
SNRNP25
C16orf33 |
small nuclear ribonucleoprotein 25kDa (U11/U12) | salinomycin results in decreased expression of SNRNP25 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 58533 |
SNX6
MSTP010 TFAF2 |
sorting nexin 6 | salinomycin results in decreased expression of SNX6 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 26010 |
SPATS2L
DNAPTP6 SGNP |
spermatogenesis associated, serine-rich 2-like | salinomycin results in decreased expression of SPATS2L mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 6696 |
SPP1
BNSP BSPI ETA-1 OPN |
secreted phosphoprotein 1 | salinomycin results in decreased expression of SPP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 6729 |
SRP54
|
signal recognition particle 54kDa | salinomycin results in decreased expression of SRP54 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 6745 |
SSR1
TRAPA |
signal sequence receptor, alpha | salinomycin results in decreased expression of SSR1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 8027 |
STAM
STAM-1 STAM1 |
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 | salinomycin results in decreased expression of STAM mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 6780 |
STAU1
STAU |
staufen double-stranded RNA binding protein 1 | salinomycin results in decreased expression of STAU1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 27347 |
STK39
DCHT PASK SPAK |
serine threonine kinase 39 (EC:2.7.11.1) | salinomycin results in decreased expression of STK39 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 25917 |
THUMPD3
|
THUMP domain containing 3 | salinomycin results in decreased expression of THUMPD3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 353376 |
TICAM2
MyD88-4 TICAM-2 TIRAP3 TIRP TRAM |
toll-like receptor adaptor molecule 2 | salinomycin results in decreased expression of TICAM2 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 7078 |
TIMP3
HSMRK222 K222 K222TA2 SFD |
TIMP metallopeptidase inhibitor 3 | salinomycin results in decreased expression of TIMP3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 3371 |
TNC
150-225 DFNA56 GMEM GP HXB JI TN TN-C |
tenascin C | salinomycin results in decreased expression of TNC mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 203068 |
TUBB
M40 OK/SW-cl.56 TUBB1 TUBB5 |
tubulin, beta class I | salinomycin results in decreased expression of TUBB mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 10381 |
TUBB3
CDCBM CDCBM1 CFEOM3A TUBB4 beta-4 |
tubulin, beta 3 class III | salinomycin results in decreased expression of TUBB3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 129450 |
TYW5
C2orf60 hTYW5 |
tRNA-yW synthesizing protein 5 | salinomycin results in decreased expression of TYW5 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 140739 |
UBE2F
NCE2 |
ubiquitin-conjugating enzyme E2F (putative) | salinomycin results in decreased expression of UBE2F mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 27338 |
UBE2S
E2-EPF E2EPF EPF5 |
ubiquitin-conjugating enzyme E2S (EC:6.3.2.19) | salinomycin results in decreased expression of UBE2S mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 54887 |
UHRF1BP1
C6orf107 ICBP90 dJ349A12.1 |
UHRF1 binding protein 1 | salinomycin results in decreased expression of UHRF1BP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 81552 |
VOPP1
ECOP GASP |
vesicular, overexpressed in cancer, prosurvival protein 1 | salinomycin results in decreased expression of VOPP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 7456 |
WIPF1
PRPL-2 WASPIP WIP |
WAS/WASL interacting protein family, member 1 | salinomycin results in decreased expression of WIPF1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 7511 |
XPNPEP1
APP1 SAMP XPNPEP XPNPEPL XPNPEPL1 |
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (EC:3.4.11.9) | salinomycin results in decreased expression of XPNPEP1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 9213 |
XPR1
SYG1 X3 |
xenotropic and polytropic retrovirus receptor 1 | salinomycin results in decreased expression of XPR1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 57002 |
YAE1D1
C7orf36 |
Yae1 domain containing 1 | salinomycin results in decreased expression of YAE1D1 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 64393 |
ZMAT3
PAG608 WIG-1 WIG1 |
zinc finger, matrin-type 3 | salinomycin results in decreased expression of ZMAT3 mRNA |
decreases expression
|
mRNA |
19682730
|
| C010327 | 79699 |
ZYG11B
ZYG11 |
zyg-11 family member B, cell cycle regulator | salinomycin results in decreased expression of ZYG11B mRNA |
decreases expression
|
mRNA |
19682730
|
Related Disease
Diseases related to proteins in ChEMBL interactions
OMIM (36)
| OMIM | preferred title | UniProt |
|---|---|---|
| #100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
| #103780 | Alcohol dependence |
P08172
P14416 P31645 |
| #614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
| #602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
| #300615 | Brunner syndrome |
P21397
|
| #162800 | Cyclic neutropenia |
P08246
|
| #612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #613659 | Gastric cancer |
P04626
|
| #137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
| #231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
| #137800 | Glioma susceptibility 1; glm1 |
P04626
|
| #609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
| #603932 | Intervertebral disc disease; idd |
P14780
|
| #613688 | Long qt syndrome 2; lqt2 |
Q12809
|
| #211980 | Lung cancer |
P00533
P04626 |
| #608516 | Major depressive disorder; mdd |
P08172
|
| %300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
| #613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
| #126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
| #159900 | Myoclonic dystonia |
P14416
|
| #202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
| #601665 | Obesity |
P32245
|
| #164230 | Obsessive-compulsive disorder; ocd |
P31645
|
| #604715 | Orthostatic intolerance |
P23975
|
| #259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
| #167000 | Ovarian cancer |
P04626
|
| #613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
| #607276 | Resting heart rate, variation in |
P08588
|
| #608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
| #609620 | Short qt syndrome 1; sqt1 |
Q12809
|
| #190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
| #610379 | West nile virus, susceptibility to |
P51681
|
| #112100 | Yt blood group antigen |
P22303
|
KEGG DISEASE (31)
| KEGG | disease name | UniProt |
|---|---|---|
| H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
| H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
| H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
| H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
| H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
| H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
| H00042 | Glioma |
P00533
(related)
P00533 (marker) |
| H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
| H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
| H00436 | Osteopetrosis |
P00918
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
| H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
| H00019 | Pancreatic cancer |
P04626
(related)
|
| H00027 | Ovarian cancer |
P04626
(related)
|
| H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
| H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
| H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
| H00079 | Asthma |
P07550
(related)
|
| H00100 | Neutropenic disorders |
P08246
(related)
|
| H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
| H00479 | Metaphyseal dysplasias |
P14780
(related)
|
| H00548 | Brunner syndrome |
P21397
(related)
|
| H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
| H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
| H00720 | Long QT syndrome |
Q12809
(related)
|
| H00725 | Short QT syndrome |
Q12809
(related)
|
Diseases related to CTD interactions
6 disease from interactions of metabolites
| MeSH disease | OMIM | compound | disease name | evidence type |
reference
pmid |
|---|---|---|---|---|---|
| D001943 | C010327 | Breast Neoplasms |
therapeutic
|
19682730
22215106 |
|
| D007938 | C010327 | Leukemia |
therapeutic
|
22215106
|
|
| D008325 | C010327 | Mammary Neoplasms, Experimental |
therapeutic
|
19682730
|
|
| D009361 | C010327 | Neoplasm Invasiveness |
therapeutic
|
22215106
|
|
| D011471 | C010327 | Prostatic Neoplasms |
therapeutic
|
22215106
|
|
| D002583 | C010327 | Uterine Cervical Neoplasms |
therapeutic
|
22215106
|