Organism name | Streptomyces albus ATCC 21838 |
---|---|
Genus | Streptomyces |
Family | Streptomycetaceae |
Kingdom | Bacteria |
Linked NCBI taxonomy name | Streptomyces |
---|---|
Linked NCBI taxonomy ID | 1883 |
Linked level | genus |
Family in NCBI taxonomy | Streptomycetaceae |
---|---|
ID | 2062 |
Kingdom (Superkingdom) in NCBI taxonomy | Bacteria |
---|---|
ID | 2 |
Plant class | |
---|---|
ID |
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
---|---|---|---|---|---|---|---|---|
C00018019
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Coxistac
/ Salinomycin / Antibiotic 61477 |
CHEMBL1208572
CHEMBL1619796 CHEMBL2135651 |
C010327
|
89 / 36 / 31 | 170 / 6 | No. 7454 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00018019 | 1 / 0 |
P21728 | D(1A) dopamine receptor | Dopamine receptor | C00018019 | 0 / 0 |
P35354 | Prostaglandin G/H synthase 2 | Oxidoreductase | C00018019 | 0 / 3 |
Q12809 | Potassium voltage-gated channel subfamily H member 2 | KCNH, Kv10-12.x (Ether-a-go-go) | C00018019 | 2 / 2 |
P08246 | Neutrophil elastase | S1A | C00018019 | 2 / 1 |
P33765 | Adenosine receptor A3 | Adenosine receptor | C00018019 | 0 / 0 |
Q16539 | Mitogen-activated protein kinase 14 | p38 | C00018019 | 0 / 0 |
P49146 | Neuropeptide Y receptor type 2 | Neuropeptide Y receptor | C00018019 | 0 / 0 |
P29466 | Caspase-1 | C14 | C00018019 | 0 / 0 |
P17252 | Protein kinase C alpha type | Alpha | C00018019 | 0 / 0 |
P27361 | Mitogen-activated protein kinase 3 | Erk | C00018019 | 0 / 0 |
P14780 | Matrix metalloproteinase-9 | M10A | C00018019 | 2 / 2 |
P00918 | Carbonic anhydrase 2 | Lyase | C00018019 | 1 / 2 |
P07550 | Beta-2 adrenergic receptor | Adrenergic receptor | C00018019 | 0 / 1 |
P21397 | Amine oxidase [flavin-containing] A | Oxidoreductase | C00018019 | 1 / 1 |
P25021 | Histamine H2 receptor | Histamine receptor | C00018019 | 0 / 0 |
P35367 | Histamine H1 receptor | Histamine receptor | C00018019 | 0 / 0 |
Q01959 | Sodium-dependent dopamine transporter | Dopamine | C00018019 | 1 / 0 |
P08912 | Muscarinic acetylcholine receptor M5 | Acetylcholine receptor | C00018019 | 0 / 0 |
P18825 | Alpha-2C adrenergic receptor | Adrenergic receptor | C00018019 | 0 / 0 |
P13945 | Beta-3 adrenergic receptor | Adrenergic receptor | C00018019 | 0 / 0 |
P25024 | C-X-C chemokine receptor type 1 | CXC chemokine receptor | C00018019 | 0 / 0 |
P06241 | Tyrosine-protein kinase Fyn | Src | C00018019 | 0 / 0 |
Q08209 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | Ser_Thr | C00018019 | 0 / 0 |
P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00018019 | 0 / 1 |
P00533 | Epidermal growth factor receptor | TK tyrosine-protein kinase EGFR subfamily | C00018019 | 1 / 8 |
P14416 | D(2) dopamine receptor | Dopamine receptor | C00018019 | 2 / 0 |
P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00018019 | 0 / 0 |
P37288 | Vasopressin V1a receptor | Vasopressin and oxytocin receptor | C00018019 | 0 / 0 |
P41145 | Kappa-type opioid receptor | Opioid receptor | C00018019 | 0 / 0 |
Q9Y271 | Cysteinyl leukotriene receptor 1 | Leukotriene receptor | C00018019 | 0 / 0 |
P29274 | Adenosine receptor A2a | Adenosine receptor | C00018019 | 0 / 0 |
P25929 | Neuropeptide Y receptor type 1 | Neuropeptide Y receptor | C00018019 | 0 / 0 |
P50052 | Type-2 angiotensin II receptor | Angiotensin receptor | C00018019 | 1 / 1 |
P17948 | Vascular endothelial growth factor receptor 1 | Vegfr | C00018019 | 0 / 0 |
P41968 | Melanocortin receptor 3 | Melanocortin receptor | C00018019 | 1 / 0 |
P11509 | Cytochrome P450 2A6 | Cytochrome P450 2A6 | C00018019 | 0 / 0 |
P04035 | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Oxidoreductase | C00018019 | 0 / 0 |
P08913 | Alpha-2A adrenergic receptor | Adrenergic receptor | C00018019 | 0 / 0 |
P21917 | D(4) dopamine receptor | Dopamine receptor | C00018019 | 0 / 0 |
P30988 | Calcitonin receptor | Calcitonin receptor | C00018019 | 0 / 0 |
P35462 | D(3) dopamine receptor | Dopamine receptor | C00018019 | 1 / 0 |
P41143 | Delta-type opioid receptor | Opioid receptor | C00018019 | 0 / 0 |
Q92731 | Estrogen receptor beta | NR3A2 | C00018019 | 0 / 1 |
P41595 | 5-hydroxytryptamine receptor 2B | Serotonin receptor | C00018019 | 0 / 0 |
P25101 | Endothelin-1 receptor | Endothelin receptor | C00018019 | 0 / 0 |
P30411 | B2 bradykinin receptor | Bradykinin receptor | C00018019 | 0 / 0 |
P32245 | Melanocortin receptor 4 | Melanocortin receptor | C00018019 | 1 / 0 |
P32238 | Cholecystokinin receptor type A | Cholecystokinin receptor | C00018019 | 0 / 0 |
P08311 | Cathepsin G | S1A | C00018019 | 0 / 0 |
Q99720 | Sigma non-opioid intracellular receptor 1 | Membrane receptor | C00018019 | 1 / 0 |
P03956 | Interstitial collagenase | M10A | C00018019 | 0 / 1 |
P32241 | Vasoactive intestinal polypeptide receptor 1 | Vasoactive intestinal peptide receptor | C00018019 | 0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00018019 | 0 / 1 |
P08172 | Muscarinic acetylcholine receptor M2 | Acetylcholine receptor | C00018019 | 2 / 0 |
P11229 | Muscarinic acetylcholine receptor M1 | Acetylcholine receptor | C00018019 | 0 / 0 |
P21554 | Cannabinoid receptor 1 | Cannabinoid receptor | C00018019 | 0 / 0 |
P31645 | Sodium-dependent serotonin transporter | Serotonin | C00018019 | 2 / 0 |
P04626 | Receptor tyrosine-protein kinase erbB-2 | TK tyrosine-protein kinase EGFR subfamily | C00018019 | 5 / 9 |
P20309 | Muscarinic acetylcholine receptor M3 | Acetylcholine receptor | C00018019 | 1 / 0 |
P21452 | Substance-K receptor | Neurokinin receptor | C00018019 | 0 / 0 |
P51679 | C-C chemokine receptor type 4 | CC chemokine receptor | C00018019 | 0 / 0 |
P51681 | C-C chemokine receptor type 5 | CC chemokine receptor | C00018019 | 3 / 0 |
P50406 | 5-hydroxytryptamine receptor 6 | Serotonin receptor | C00018019 | 0 / 0 |
P41597 | C-C chemokine receptor type 2 | CC chemokine receptor | C00018019 | 1 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00018019 | 0 / 0 |
P08575 | Receptor-type tyrosine-protein phosphatase C | Enzyme | C00018019 | 2 / 1 |
P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00018019 | 0 / 0 |
O76074 | cGMP-specific 3',5'-cyclic phosphodiesterase | PDE_5A | C00018019 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00018019 | 1 / 1 |
P08588 | Beta-1 adrenergic receptor | Adrenergic receptor | C00018019 | 1 / 0 |
P22303 | Acetylcholinesterase | Hydrolase | C00018019 | 1 / 0 |
P28223 | 5-hydroxytryptamine receptor 2A | Serotonin receptor | C00018019 | 0 / 0 |
P28335 | 5-hydroxytryptamine receptor 2C | Serotonin receptor | C00018019 | 0 / 0 |
P35372 | Mu-type opioid receptor | Opioid receptor | C00018019 | 0 / 0 |
P08173 | Muscarinic acetylcholine receptor M4 | Acetylcholine receptor | C00018019 | 0 / 0 |
P25103 | Substance-P receptor | Neurokinin receptor | C00018019 | 0 / 0 |
P25105 | Platelet-activating factor receptor | PAF receptor | C00018019 | 0 / 0 |
P33032 | Melanocortin receptor 5 | Melanocortin receptor | C00018019 | 0 / 0 |
P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00018019 | 1 / 1 |
P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00018019 | 0 / 1 |
P05181 | Cytochrome P450 2E1 | Cytochrome P450 2E1 | C00018019 | 0 / 0 |
P23975 | Sodium-dependent noradrenaline transporter | Norepinephrine | C00018019 | 1 / 1 |
P25100 | Alpha-1D adrenergic receptor | Adrenergic receptor | C00018019 | 0 / 0 |
P30542 | Adenosine receptor A1 | Adenosine receptor | C00018019 | 0 / 0 |
P18089 | Alpha-2B adrenergic receptor | Adrenergic receptor | C00018019 | 0 / 0 |
P24557 | Thromboxane-A synthase | Cytochrome P450 5A1 | C00018019 | 1 / 1 |
P06239 | Tyrosine-protein kinase Lck | Src | C00018019 | 0 / 1 |
P25025 | C-X-C chemokine receptor type 2 | CXC chemokine receptor | C00018019 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
55856 | ACOT13, PNAS-27, THEM2 | acyl-CoA thioesterase 13 |
C00018019
|
71 | ACTG1, ACT, ACTG, BRWS2, DFNA20, DFNA26 | actin, gamma 1 |
C00018019
|
8038 | ADAM12, MCMP, MCMPMltna, MLTN, MLTNA | ADAM metallopeptidase domain 12 |
C00018019
|
165 | AEBP1, ACLP | AE binding protein 1 |
C00018019
|
8540 | AGPS, ADAP-S, ADAS, ADHAPS, ADPS, ALDHPSY | alkylglycerone phosphate synthase (EC:2.5.1.26) |
C00018019
|
64853 | AIDA, C1orf80, RP11-378J18.7 | axin interactor, dorsalization associated |
C00018019
|
7965 | AIMP2, JTV-1, JTV1, P38 | aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 |
C00018019
|
85365 | ALG2, CDGIi, NET38, hALPG2 | ALG2, alpha-1,3/1,6-mannosyltransferase (EC:2.4.1.132 2.4.1.257) |
C00018019
|
8846 | ALKBH1, ABH, ABH1, ALKBH, alkB, hABH | alkB, alkylation repair homolog 1 (E. coli) (EC:4.2.99.18 1.14.11.33) |
C00018019
|
9949 | AMMECR1, AMMERC1 | Alport syndrome, mental retardation, midface hypoplasia and elliptocytosis chromosomal region gene 1 |
C00018019
|
81573 | ANKRD13C, RP4-677H15.5, dJ677H15.3 | ankyrin repeat domain 13C |
C00018019
|
308 | ANXA5, ANX5, ENX2, PP4, RPRGL3 | annexin A5 |
C00018019
|
367 | AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM | androgen receptor |
C00018019
|
116985 | ARAP1, CENTD2 | ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1 |
C00018019
|
377 | ARF3 | ADP-ribosylation factor 3 |
C00018019
|
10092 | ARPC5, ARC16, dJ127C7.3, p16-Arc | actin related protein 2/3 complex, subunit 5, 16kDa |
C00018019
|
467 | ATF3 | activating transcription factor 3 |
C00018019
|
471 | ATIC, AICAR, AICARFT, IMPCHASE, PURH | 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase (EC:2.1.2.3 3.5.4.10) |
C00018019
|
79572 | ATP13A3, AFURS1 | ATPase type 13A3 |
C00018019
|
483 | ATP1B3, ATPB-3, CD298 | ATPase, Na+/K+ transporting, beta 3 polypeptide (EC:3.6.3.9) |
C00018019
|
4287 | ATXN3, AT3, ATX3, JOS, MJD, MJD1, SCA3 | ataxin 3 (EC:3.4.19.12) |
C00018019
|
7917 | BAG6, BAG-6, BAT3, D6S52E, G3 | BCL2-associated athanogene 6 |
C00018019
|
79020 | C7orf25 | chromosome 7 open reading frame 25 |
C00018019
|
84267 | C9orf64 | chromosome 9 open reading frame 64 |
C00018019
|
800 | CALD1, CDM, H-CAD, HCAD, L-CAD, LCAD, NAG22 | caldesmon 1 |
C00018019
|
841 | CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 | caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) |
C00018019
|
124808 | CCDC43 | coiled-coil domain containing 43 |
C00018019
|
6347 | CCL2, GDCF-2, HC11, HSMCR30, MCAF, MCP-1, MCP1, SCYA2, SMC-CF | chemokine (C-C motif) ligand 2 |
C00018019
|
894 | CCND2, KIAK0002 | cyclin D2 |
C00018019
|
219771 | CCNY, C10orf9, CBCP1, CCNX, CFP1 | cyclin Y |
C00018019
|
8872 | CDC123, C10orf7, D123 | cell division cycle 123 |
C00018019
|
9857 | CEP350, CAP350, GM133 | centrosomal protein 350kDa |
C00018019
|
6320 | CLEC11A, CLECSF3, LSLCL, P47, SCGF | C-type lectin domain family 11, member A |
C00018019
|
1192 | CLIC1, G6, NCC27 | chloride intracellular channel 1 |
C00018019
|
1213 | CLTC, CHC, CHC17, CLH-17, CLTCL2, Hc | clathrin, heavy chain (Hc) |
C00018019
|
29097 | CNIH4, CNIH-4 | cornichon family AMPA receptor auxiliary protein 4 |
C00018019
|
4850 | CNOT4, CLONE243, NOT4, NOT4H | CCR4-NOT transcription complex, subunit 4 |
C00018019
|
9276 | COPB2, beta'-COP | coatomer protein complex, subunit beta 2 (beta prime) |
C00018019
|
1457 | CSNK2A1, CK2A1, CKII, CSNK2A3 | casein kinase 2, alpha 1 polypeptide (EC:2.7.11.1) |
C00018019
|
1477 | CSTF1, CstF-50, CstFp50 | cleavage stimulation factor, 3' pre-RNA, subunit 1, 50kDa |
C00018019
|
1486 | CTBS, CTB | chitobiase, di-N-acetyl- (EC:3.2.1.-) |
C00018019
|
51163 | DBR1 | debranching RNA lariats 1 |
C00018019
|
10238 | DCAF7, AN11, HAN11, SWAN-1, WDR68 | DDB1 and CUL4 associated factor 7 |
C00018019
|
285761 | DCBLD1, dJ94G16.1 | discoidin, CUB and LCCL domain containing 1 |
C00018019
|
1634 | DCN, CSCD, DSPG2, PG40, PGII, PGS2, SLRR1B | decorin |
C00018019
|
23142 | DCUN1D4 | DCN1, defective in cullin neddylation 1, domain containing 4 |
C00018019
|
1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00018019
|
54541 | DDIT4, Dig2, REDD-1, REDD1 | DNA-damage-inducible transcript 4 |
C00018019
|
51029 | DESI2, C1orf121, DESI, DESI1, DeSI-2, FAM152A, PNAS-4, PPPDE1 | desumoylating isopeptidase 2 |
C00018019
|
23317 | DNAJC13, RME8 | DnaJ (Hsp40) homolog, subfamily C, member 13 |
C00018019
|
1788 | DNMT3A, DNMT3A2, M.HsaIIIA | DNA (cytosine-5-)-methyltransferase 3 alpha (EC:2.1.1.37) |
C00018019
|
5977 | DPF2, REQ, UBID4, ubi-d4 | D4, zinc and double PHD fingers family 2 |
C00018019
|
1809 | DPYSL3, CRMP-4, CRMP4, DRP-3, DRP3, LCRMP, ULIP, ULIP-1 | dihydropyrimidinase-like 3 |
C00018019
|
1857 | DVL3 | dishevelled segment polarity protein 3 |
C00018019
|
9470 | EIF4E2, 4E-LP, 4EHP, EIF4EL3, IF4e | eukaryotic translation initiation factor 4E family member 2 |
C00018019
|
26610 | ELP4, C11orf19, PAX6NEB, PAXNEB, dJ68P15A.1 | elongator acetyltransferase complex subunit 4 |
C00018019
|
2014 | EMP3, YMP | epithelial membrane protein 3 |
C00018019
|
2078 | ERG, erg-3, p55 | v-ets avian erythroblastosis virus E26 oncogene homolog |
C00018019
|
54465 | ETAA1, ETAA16 | Ewing tumor-associated antigen 1 |
C00018019
|
2131 | EXT1, EXT, LGCR, LGS, TRPS2, TTV | exostosin glycosyltransferase 1 (EC:2.4.1.225 2.4.1.224) |
C00018019
|
57700 | FAM160B1, KIAA1600, bA106M7.3 | family with sequence similarity 160, member B1 |
C00018019
|
2260 | FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 | fibroblast growth factor receptor 1 (EC:2.7.10.1) |
C00018019
|
83856 | FSD1L, CCDC10, CSDUFD1, FSD1CL, FSD1NL, MIR1 | fibronectin type III and SPRY domain containing 1-like |
C00018019
|
2512 | FTL, NBIA3 | ferritin, light polypeptide |
C00018019
|
2534 | FYN, SLK, SYN, p59-FYN | FYN oncogene related to SRC, FGR, YES (EC:2.7.10.2) |
C00018019
|
2535 | FZD2, Fz2, fz-2, fzE2, hFz2 | frizzled family receptor 2 |
C00018019
|
2596 | GAP43, B-50, PP46 | growth associated protein 43 |
C00018019
|
2597 | GAPDH, G3PD, GAPD | glyceraldehyde-3-phosphate dehydrogenase (EC:1.2.1.12) |
C00018019
|
2621 | GAS6, AXLLG, AXSF | growth arrest-specific 6 |
C00018019
|
2690 | GHR, GHBP | growth hormone receptor |
C00018019
|
10399 | GNB2L1, Gnb2-rs1, H12.3, HLC-7, PIG21, RACK1 | guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 |
C00018019
|
10007 | GNPDA1, GNP1, GNPDA, GNPI, GPI, HLN | glucosamine-6-phosphate deaminase 1 (EC:3.5.99.6) |
C00018019
|
92344 | GORAB, GO, NTKLBP1, SCYL1BP1 | golgin, RAB6-interacting |
C00018019
|
2239 | GPC4, K-glypican | glypican 4 |
C00018019
|
10457 | GPNMB, HGFIN, NMB | glycoprotein (transmembrane) nmb |
C00018019
|
9052 | GPRC5A, GPCR5A, RAI3, RAIG1 | G protein-coupled receptor, family C, group 5, member A |
C00018019
|
2932 | GSK3B | glycogen synthase kinase 3 beta (EC:2.7.11.1 2.7.11.26) |
C00018019
|
9330 | GTF3C3, TFIIIC102, TFIIICgamma, TFiiiC2-102 | general transcription factor IIIC, polypeptide 3, 102kDa |
C00018019
|
3091 | HIF1A, HIF-1A, HIF-1alpha, HIF1, HIF1-ALPHA, MOP1, PASD8, bHLHe78 | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) |
C00018019
|
9653 | HS2ST1, dJ604K5.2 | heparan sulfate 2-O-sulfotransferase 1 (EC:2.8.2.-) |
C00018019
|
23463 | ICMT, HSTE14, MST098, MSTP098, PCCMT, PCMT, PPMT | isoprenylcysteine carboxyl methyltransferase (EC:2.1.1.100) |
C00018019
|
3482 | IGF2R, CD222, CIMPR, M6P-R, MPR1, MPRI | insulin-like growth factor 2 receptor |
C00018019
|
3487 | IGFBP4, BP-4, HT29-IGFBP, IBP4, IGFBP-4 | insulin-like growth factor binding protein 4 |
C00018019
|
3490 | IGFBP7, AGM, FSTL2, IBP-7, IGFBP-7, IGFBP-7v, IGFBPRP1, MAC25, PSF, RAMSVPS, TAF | insulin-like growth factor binding protein 7 |
C00018019
|
57508 | INTS2, INT2, KIAA1287 | integrator complex subunit 2 |
C00018019
|
55656 | INTS8, C8orf52, INT8 | integrator complex subunit 8 |
C00018019
|
10379 | IRF9, IRF-9, ISGF3, ISGF3G, p48 | interferon regulatory factor 9 |
C00018019
|
11014 | KDELR2, ELP-1, ERD2.2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 |
C00018019
|
11015 | KDELR3, ERD2L3 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3 |
C00018019
|
1316 | KLF6, BCD1, CBA1, COPEB, CPBP, GBF, PAC1, ST12, ZF9 | Kruppel-like factor 6 |
C00018019
|
27252 | KLHL20, KHLHX, KLEIP, KLHLX, RP3-383J4.3 | kelch-like family member 20 |
C00018019
|
354 | KLK3, APS, KLK2A1, PSA, hK3 | kallikrein-related peptidase 3 (EC:3.4.21.77) |
C00018019
|
23367 | LARP1, LARP | La ribonucleoprotein domain family, member 1 |
C00018019
|
3939 | LDHA, GSD11, LDH1, LDHM | lactate dehydrogenase A (EC:1.1.1.27) |
C00018019
|
257103 |
C00018019
|
||
64327 | LMBR1, ACHP, C7orf2, DIF14, PPD2, TPT, ZRS | limb development membrane protein 1 |
C00018019
|
9663 | LPIN2 | lipin 2 (EC:3.1.3.4) |
C00018019
|
1432 | MAPK14, CSBP, CSBP1, CSBP2, CSPB1, EXIP, Mxi2, PRKM14, PRKM15, RK, SAPK2A, p38, p38ALPHA | mitogen-activated protein kinase 14 (EC:2.7.11.24) |
C00018019
|
4141 | MARS, METRS, MRS, MTRNS | methionyl-tRNA synthetase (EC:6.1.1.10) |
C00018019
|
4319 | MMP10, SL-2, STMY2 | matrix metallopeptidase 10 (stromelysin 2) (EC:3.4.24.22) |
C00018019
|
4323 | MMP14, MMP-14, MMP-X1, MT-MMP, MT-MMP_1, MT1-MMP, MT1MMP, MTMMP1, WNCHRS | matrix metallopeptidase 14 (membrane-inserted) (EC:3.4.24.80) |
C00018019
|
4494 | MT1F, MT1 | metallothionein 1F |
C00018019
|
4495 | MT1G, MT1, MT1K | metallothionein 1G |
C00018019
|
4502 | MT2A, MT2 | metallothionein 2A |
C00018019
|
4609 | MYC, MRTL, MYCC, bHLHe39, c-Myc | v-myc avian myelocytomatosis viral oncogene homolog |
C00018019
|
4651 | MYO10 | myosin X |
C00018019
|
55226 | NAT10, ALP, NET43 | N-acetyltransferase 10 (GCN5-related) (EC:2.3.1.-) |
C00018019
|
4811 | NID1, NID | nidogen 1 |
C00018019
|
22795 | NID2, NID-2 | nidogen 2 (osteonidogen) |
C00018019
|
55035 | NOL8, C9orf34, NOP132, bA62C3.3, bA62C3.4 | nucleolar protein 8 |
C00018019
|
4854 | NOTCH3, CADASIL, CASIL, IMF2 | notch 3 |
C00018019
|
4905 | NSF, SKD2 | N-ethylmaleimide-sensitive factor (EC:3.6.4.6) |
C00018019
|
81788 | NUAK2, SNARK | NUAK family, SNF1-like kinase, 2 (EC:2.7.11.1) |
C00018019
|
64710 | NUCKS1, NUCKS | nuclear casein kinase and cyclin-dependent kinase substrate 1 |
C00018019
|
11164 | NUDT5, YSA1, YSA1H, YSAH1, hYSAH1 | nudix (nucleoside diphosphate linked moiety X)-type motif 5 (EC:3.6.1.13 3.6.1.58) |
C00018019
|
79023 | NUP37, p37 | nucleoporin 37kDa |
C00018019
|
23636 | NUP62, IBSN, SNDI, p62 | nucleoporin 62kDa |
C00018019
|
5062 | PAK2, PAK65, PAKgamma | p21 protein (Cdc42/Rac)-activated kinase 2 (EC:2.7.11.1) |
C00018019
|
5151 | PDE8A, HsT19550 | phosphodiesterase 8A (EC:3.1.4.17) |
C00018019
|
5159 | PDGFRB, CD140B, IBGC4, IMF1, JTK12, PDGFR, PDGFR-1, PDGFR1 | platelet-derived growth factor receptor, beta polypeptide (EC:2.7.10.1) |
C00018019
|
5209 | PFKFB3, IPFK2, PFK2 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3 (EC:2.7.1.105 3.1.3.46) |
C00018019
|
5230 | PGK1, MIG10, PGKA | phosphoglycerate kinase 1 (EC:2.7.2.3) |
C00018019
|
5311 | PKD2, APKD2, PC2, PKD4, Pc-2, TRPP2 | polycystic kidney disease 2 (autosomal dominant) |
C00018019
|
9373 | PLAA, DOA1, PLA2P, PLAP | phospholipase A2-activating protein |
C00018019
|
5352 | PLOD2, LH2, TLH | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 (EC:1.14.11.4) |
C00018019
|
5355 | PLP2, A4, A4LSB | proteolipid protein 2 (colonic epithelium-enriched) |
C00018019
|
25953 | PNKD, BRP17, DYT8, FPD1, KIPP1184, MR-1, MR1, PDC, PKND1, TAHCCP2 | paroxysmal nonkinesigenic dyskinesia (EC:3.1.2.6) |
C00018019
|
9581 | PREPL | prolyl endopeptidase-like (EC:3.4.21.-) |
C00018019
|
5686 | PSMA5, PSC5, ZETA | proteasome (prosome, macropain) subunit, alpha type, 5 (EC:3.4.25.1) |
C00018019
|
5695 | PSMB7, Z | proteasome (prosome, macropain) subunit, beta type, 7 (EC:3.4.25.1) |
C00018019
|
5714 | PSMD8, HIP6, HYPF, Nin1p, Rpn12, S14, p31 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 8 |
C00018019
|
53635 | PTOV1, ACID2, PTOV-1 | prostate tumor overexpressed 1 |
C00018019
|
51715 | RAB23, HSPC137 | RAB23, member RAS oncogene family |
C00018019
|
5887 | RAD23B, HHR23B, HR23B, P58 | RAD23 homolog B (S. cerevisiae) |
C00018019
|
54453 | RIN2, MACS, RASSF4 | Ras and Rab interactor 2 |
C00018019
|
9025 | RNF8, hRNF8 | ring finger protein 8, E3 ubiquitin protein ligase (EC:6.3.2.-) |
C00018019
|
23429 | RYBP, AAP1, DEDAF, YEAF1 | RING1 and YY1 binding protein |
C00018019
|
79005 | SCNM1 | sodium channel modifier 1 |
C00018019
|
51150 | SDF4, Cab45, SDF-4 | stromal cell derived factor 4 |
C00018019
|
65260 | SELRC1, C1orf163 | Sel1 repeat containing 1 |
C00018019
|
55209 | SETD5 | SET domain containing 5 |
C00018019
|
23517 | SKIV2L2, Dob1, KIAA0052, Mtr4, fSAP118 | superkiller viralicidic activity 2-like 2 (S. cerevisiae) (EC:3.6.4.13) |
C00018019
|
153129 | SLC38A9 | solute carrier family 38, member 9 |
C00018019
|
55181 | SMG8, C17orf71 | SMG8 nonsense mediated mRNA decay factor |
C00018019
|
79622 | SNRNP25, C16orf33 | small nuclear ribonucleoprotein 25kDa (U11/U12) |
C00018019
|
58533 | SNX6, MSTP010, TFAF2 | sorting nexin 6 |
C00018019
|
26010 | SPATS2L, DNAPTP6, SGNP | spermatogenesis associated, serine-rich 2-like |
C00018019
|
6696 | SPP1, BNSP, BSPI, ETA-1, OPN | secreted phosphoprotein 1 |
C00018019
|
6729 | SRP54 | signal recognition particle 54kDa |
C00018019
|
6745 | SSR1, TRAPA | signal sequence receptor, alpha |
C00018019
|
8027 | STAM, STAM-1, STAM1 | signal transducing adaptor molecule (SH3 domain and ITAM motif) 1 |
C00018019
|
6780 | STAU1, STAU | staufen double-stranded RNA binding protein 1 |
C00018019
|
27347 | STK39, DCHT, PASK, SPAK | serine threonine kinase 39 (EC:2.7.11.1) |
C00018019
|
25917 | THUMPD3 | THUMP domain containing 3 |
C00018019
|
353376 | TICAM2, MyD88-4, TICAM-2, TIRAP3, TIRP, TRAM | toll-like receptor adaptor molecule 2 |
C00018019
|
7078 | TIMP3, HSMRK222, K222, K222TA2, SFD | TIMP metallopeptidase inhibitor 3 |
C00018019
|
3371 | TNC, 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C | tenascin C |
C00018019
|
203068 | TUBB, M40, OK/SW-cl.56, TUBB1, TUBB5 | tubulin, beta class I |
C00018019
|
10381 | TUBB3, CDCBM, CDCBM1, CFEOM3A, TUBB4, beta-4 | tubulin, beta 3 class III |
C00018019
|
129450 | TYW5, C2orf60, hTYW5 | tRNA-yW synthesizing protein 5 |
C00018019
|
140739 | UBE2F, NCE2 | ubiquitin-conjugating enzyme E2F (putative) |
C00018019
|
27338 | UBE2S, E2-EPF, E2EPF, EPF5 | ubiquitin-conjugating enzyme E2S (EC:6.3.2.19) |
C00018019
|
54887 | UHRF1BP1, C6orf107, ICBP90, dJ349A12.1 | UHRF1 binding protein 1 |
C00018019
|
81552 | VOPP1, ECOP, GASP | vesicular, overexpressed in cancer, prosurvival protein 1 |
C00018019
|
7456 | WIPF1, PRPL-2, WASPIP, WIP | WAS/WASL interacting protein family, member 1 |
C00018019
|
7511 | XPNPEP1, APP1, SAMP, XPNPEP, XPNPEPL, XPNPEPL1 | X-prolyl aminopeptidase (aminopeptidase P) 1, soluble (EC:3.4.11.9) |
C00018019
|
9213 | XPR1, SYG1, X3 | xenotropic and polytropic retrovirus receptor 1 |
C00018019
|
57002 | YAE1D1, C7orf36 | Yae1 domain containing 1 |
C00018019
|
64393 | ZMAT3, PAG608, WIG-1, WIG1 | zinc finger, matrin-type 3 |
C00018019
|
79699 | ZYG11B, ZYG11 | zyg-11 family member B, cell cycle regulator |
C00018019
|
OMIM | preferred title | UniProt |
---|---|---|
#100100 | Abdominal muscles, absence of, with urinary tract abnormality and cryptorchidism |
P20309
|
#103780 | Alcohol dependence |
P08172
P14416 P31645 |
#614373 | Amyotrophic lateral sclerosis 16, juvenile; als16 |
Q99720
|
#602025 | Body mass index quantitative trait locus 9; bmiq9 |
P41968
|
#300615 | Brunner syndrome |
P21397
|
#162800 | Cyclic neutropenia |
P08246
|
#612522 | Diabetes mellitus, insulin-dependent, 22; iddm22 |
P51681
|
#609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
#608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
#615363 | Estrogen resistance; estrr |
P03372
|
#613659 | Gastric cancer |
P04626
|
#137215 | Gastric cancer, hereditary diffuse; hdgc |
P04626
|
#231095 | Ghosal hematodiaphyseal dysplasia; ghdd |
P24557
|
#137800 | Glioma susceptibility 1; glm1 |
P04626
|
#609423 | Human immunodeficiency virus type 1, susceptibility to |
P41597
P51681 |
#603932 | Intervertebral disc disease; idd |
P14780
|
#613688 | Long qt syndrome 2; lqt2 |
Q12809
|
#211980 | Lung cancer |
P00533
P04626 |
#608516 | Major depressive disorder; mdd |
P08172
|
%300852 | Mental retardation, x-linked 88; mrx88 |
P50052
|
#613073 | Metaphyseal anadysplasia 2; mandp2 |
P14780
|
#126200 | Multiple sclerosis, susceptibility to; ms |
P08575
|
#159900 | Myoclonic dystonia |
P14416
|
#202700 | Neutropenia, severe congenital, 1, autosomal dominant; scn1 |
P08246
|
#601665 | Obesity |
P32245
|
#164230 | Obsessive-compulsive disorder; ocd |
P31645
|
#604715 | Orthostatic intolerance |
P23975
|
#259730 | Osteopetrosis, autosomal recessive 3; optb3 |
P00918
|
#167000 | Ovarian cancer |
P04626
|
#613135 | Parkinsonism-dystonia, infantile; pkdys |
Q01959
|
#607276 | Resting heart rate, variation in |
P08588
|
#608971 | Severe combined immunodeficiency, autosomal recessive, t cell-negative, b cell-positive, nk cell-positive |
P08575
|
#609620 | Short qt syndrome 1; sqt1 |
Q12809
|
#190300 | Tremor, hereditary essential, 1; etm1 |
P35462
|
#610379 | West nile virus, susceptibility to |
P51681
|
#112100 | Yt blood group antigen |
P22303
|
KEGG | name | UniProt |
---|---|---|
H00016 | Oral cancer |
P00533
(related)
P00533 (marker) |
H00017 | Esophageal cancer |
P00533
(related)
P35354 (related) |
H00018 | Gastric cancer |
P00533
(related)
P04626 (related) |
H00022 | Bladder cancer |
P00533
(related)
P04626 (related) |
H00028 | Choriocarcinoma |
P00533
(related)
P03956 (related) P04626 (related) |
H00030 | Cervical cancer |
P00533
(related)
P04626 (related) |
H00042 | Glioma |
P00533
(related)
P00533 (marker) |
H00055 | Laryngeal cancer |
P00533
(related)
P00533 (marker) |
H00241 | Combined proximal and distal renal tubular acidosis (RTA type 3) |
P00918
(related)
|
H00436 | Osteopetrosis |
P00918
(related)
|
H00026 | Endometrial Cancer |
P03372
(marker)
P04626 (related) Q92731 (marker) |
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00019 | Pancreatic cancer |
P04626
(related)
|
H00027 | Ovarian cancer |
P04626
(related)
|
H00031 | Breast cancer |
P04626
(related)
P04626 (marker) |
H00046 | Cholangiocarcinoma |
P04626
(related)
P35354 (related) |
H00093 | Combined immunodeficiencies (CIDs) |
P06239
(related)
|
H00079 | Asthma |
P07550
(related)
|
H00100 | Neutropenic disorders |
P08246
(related)
|
H00091 | T-B+Severe combined immunodeficiencies (SCIDs) |
P08575
(related)
|
H00036 | Osteosarcoma |
P08684
(marker)
|
H01205 | Coumarin resistance |
P11712
(related)
|
H00025 | Penile cancer |
P14780
(related)
P35354 (related) |
H00479 | Metaphyseal dysplasias |
P14780
(related)
|
H00548 | Brunner syndrome |
P21397
(related)
|
H01031 | Orthostatic intolerance (OI) |
P23975
(related)
|
H00490 | Diaphyseal dysplasia with anemia (Ghosal) |
P24557
(related)
|
H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
H00480 | Non-syndromic X-linked mental retardation |
P50052
(related)
|
H00720 | Long QT syndrome |
Q12809
(related)
|
H00725 | Short QT syndrome |
Q12809
(related)
|
MESH or OMIM | name |
KNApSAcK
metabolite |
---|---|---|
D001943 | Breast Neoplasms |
C00018019
|
D007938 | Leukemia |
C00018019
|
D008325 | Mammary Neoplasms, Experimental |
C00018019
|
D009361 | Neoplasm Invasiveness |
C00018019
|
D011471 | Prostatic Neoplasms |
C00018019
|
D002583 | Uterine Cervical Neoplasms |
C00018019
|