class name | count |
---|
class name | count |
---|---|
Aspergillaceae | 18 |
Thermoascaceae | 1 |
Gymnoascaceae | 1 |
br08003 Category | # of metabolite |
---|
br08003 Category | KEGG ID | KNApSAcK ID |
---|
KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
---|---|---|---|---|---|---|
C00024000
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Mycoin
/ Patulin / Clavitin / Tercinin / Leucopin / Clavicin / Expansion / Penicidin / Claviformin / 4-Hydroxy-4H-furo[3,2-c]pyran-2(6H)-one |
CHEMBL294018
|
D010365
|
21 / 26 / 48 | 23 / 2 |
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accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
---|---|---|---|---|
P04637 | Cellular tumor antigen p53 | Transcription Factor | C00024000 | 7 / 37 |
Q16637 | Survival motor neuron protein | Unclassified protein | C00024000 | 4 / 1 |
Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00024000 | 0 / 0 |
P10828 | Thyroid hormone receptor beta | NR1A2 | C00024000 | 3 / 1 |
P19793 | Retinoic acid receptor RXR-alpha | NR2B1 | C00024000 | 0 / 0 |
P06493 | Cyclin-dependent kinase 1 | Cdc2 | C00024000 | 0 / 0 |
P11473 | Vitamin D3 receptor | NR1I1 | C00024000 | 2 / 3 |
P00352 | Retinal dehydrogenase 1 | Enzyme | C00024000 | 0 / 0 |
P23528 | Cofilin-1 | Unclassified protein | C00024000 | 0 / 0 |
P11021 | 78 kDa glucose-regulated protein | Unclassified protein | C00024000 | 0 / 0 |
O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00024000 | 0 / 0 |
P04150 | Glucocorticoid receptor | NR3C1 | C00024000 | 0 / 1 |
P37231 | Peroxisome proliferator-activated receptor gamma | NR1C3 | C00024000 | 5 / 3 |
Q96RI1 | Bile acid receptor | NR1H4 | C00024000 | 0 / 0 |
P28482 | Mitogen-activated protein kinase 1 | Erk | C00024000 | 0 / 0 |
P03372 | Estrogen receptor | NR3A1 | C00024000 | 1 / 1 |
P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00024000 | 0 / 0 |
P10636 | Microtubule-associated protein tau | Unclassified protein | C00024000 | 4 / 3 |
P05412 | Transcription factor AP-1 | Transcription Factor | C00024000 | 0 / 0 |
P35869 | Aryl hydrocarbon receptor | Transcription Factor | C00024000 | 0 / 0 |
Q9UBT6 | DNA polymerase kappa | Enzyme | C00024000 | 0 / 0 |
gene | gene name | gene description | KNApSAcK metabolite in interactions |
---|---|---|---|
467 | ATF3 | activating transcription factor 3 |
C00024000
|
10018 | BCL2L11, BAM, BIM, BOD | BCL2-like 11 (apoptosis facilitator) |
C00024000
|
637 | BID, FP497 | BH3 interacting domain death agonist |
C00024000
|
847 | CAT | catalase (EC:1.11.1.6) |
C00024000
|
9076 | CLDN1, CLD1, ILVASC, SEMP1 | claudin 1 |
C00024000
|
1365 | CLDN3, C7orf1, CPE-R2, CPETR2, HRVP1, RVP1 | claudin 3 |
C00024000
|
1364 | CLDN4, CPE-R, CPER, CPETR, CPETR1, WBSCR8, hCPE-R | claudin 4 |
C00024000
|
1649 | DDIT3, CEBPZ, CHOP, CHOP-10, CHOP10, GADD153 | DNA-damage-inducible transcript 3 |
C00024000
|
3458 | IFNG, IFG, IFI | interferon, gamma |
C00024000
|
3586 | IL10, CSIF, GVHDS, IL-10, IL10A, TGIF | interleukin 10 |
C00024000
|
3596 | IL13, IL-13, P600 | interleukin 13 |
C00024000
|
3553 | IL1B, IL-1, IL1-BETA, IL1F2 | interleukin 1, beta |
C00024000
|
3565 | IL4, BCGF-1, BCGF1, BSF-1, BSF1, IL-4 | interleukin 4 |
C00024000
|
3576 | IL8, CXCL8, GCP-1, GCP1, LECT, LUCT, LYNAP, MDNCF, MONAP, NAF, NAP-1, NAP1 | interleukin 8 |
C00024000
|
5594 | MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk | mitogen-activated protein kinase 1 (EC:2.7.11.24) |
C00024000
|
5595 | MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK | mitogen-activated protein kinase 3 (EC:2.7.11.24) |
C00024000
|
100506658 | OCLN, BLCPMG | occludin (EC:2.1.1.67) |
C00024000
|
5366 | PMAIP1, APR, NOXA | phorbol-12-myristate-13-acetate-induced protein 1 |
C00024000
|
23645 | PPP1R15A, GADD34 | protein phosphatase 1, regulatory subunit 15A |
C00024000
|
6647 | SOD1, ALS, ALS1, IPOA, SOD, hSod1, homodimer | superoxide dismutase 1, soluble (EC:1.15.1.1) |
C00024000
|
7082 | TJP1, ZO-1 | tight junction protein 1 |
C00024000
|
7157 | TP53, BCC7, LFS1, P53, TRP53 | tumor protein p53 |
C00024000
|
7494 | XBP1, TREB5, XBP-1, XBP2 | X-box binding protein 1 |
C00024000
|
OMIM | preferred title | UniProt |
---|---|---|
#202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
#614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
%606641 | Body mass index; bmi |
P37231
|
#609338 | Carotid intimal medial thickness 1 |
P37231
|
#133239 | Esophageal cancer |
P04637
|
#615363 | Estrogen resistance; estrr |
P03372
|
#600274 | Frontotemporal dementia; ftd |
P10636
|
#137800 | Glioma susceptibility 1; glm1 |
P37231
|
#151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
#604367 | Lipodystrophy, familial partial, type 3; fpld3 |
P37231
|
#211980 | Lung cancer |
P04637
|
#607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
#601665 | Obesity |
P37231
|
#260500 | Papilloma of choroid plexus; cpp |
P04637
|
#260540 | Parkinson-dementia syndrome |
P10636
|
#172700 | Pick disease of brain |
P10636
|
#253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
#253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
#253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
#271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
#275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
#601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
#188570 | Thyroid hormone resistance, generalized, autosomal dominant; grth |
P10828
|
#274300 | Thyroid hormone resistance, generalized, autosomal recessive; grth |
P10828
|
#145650 | Thyroid hormone resistance, selective pituitary; prth |
P10828
|
#277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG | name | UniProt |
---|---|---|
H00026 | Endometrial Cancer |
P03372
(marker)
P04637 (related) |
H00599 | 46,XX disorders of sex development (Disorders related to androgen excess) |
P04150
(related)
|
H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
H00006 | Hairy-cell leukemia |
P04637
(related)
|
H00008 | Burkitt lymphoma |
P04637
(related)
|
H00009 | Adult T-cell leukemia |
P04637
(related)
|
H00010 | Multiple myeloma |
P04637
(related)
|
H00013 | Small cell lung cancer |
P04637
(related)
|
H00014 | Non-small cell lung cancer |
P04637
(related)
|
H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
H00018 | Gastric cancer |
P04637
(related)
|
H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
H00022 | Bladder cancer |
P04637
(related)
|
H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
H00027 | Ovarian cancer |
P04637
(related)
|
H00028 | Choriocarcinoma |
P04637
(related)
|
H00029 | Vulvar cancer |
P04637
(related)
|
H00031 | Breast cancer |
P04637
(related)
|
H00032 | Thyroid cancer |
P04637
(related)
P37231 (related) |
H00033 | Adrenal carcinoma |
P04637
(related)
|
H00036 | Osteosarcoma |
P04637
(related)
|
H00038 | Malignant melanoma |
P04637
(related)
|
H00039 | Basal cell carcinoma |
P04637
(related)
|
H00040 | Squamous cell carcinoma |
P04637
(related)
|
H00041 | Kaposi's sarcoma |
P04637
(related)
|
H00042 | Glioma |
P04637
(related)
P04637 (marker) |
H00044 | Cancer of the anal canal |
P04637
(related)
|
H00046 | Cholangiocarcinoma |
P04637
(related)
|
H00047 | Gallbladder cancer |
P04637
(related)
|
H00048 | Hepatocellular carcinoma |
P04637
(related)
|
H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
H01007 | Choroid plexus papilloma |
P04637
(related)
|
H00021 | Renal cell carcinoma |
P04637
(marker)
|
H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
H00249 | Thyroid hormone resistance syndrome |
P10828
(related)
|
H00342 | Tuberculosis |
P11473
(related)
|
H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
H00409 | Type II diabetes mellitus |
P37231
(related)
|
H00420 | Familial partial lipodystrophy (FPL) |
P37231
(related)
|
H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|