PCIDB

KCF-S cluster No. 8212 (1 metabolites)

Plant Species

Cumulative plant class count

class name count

Cumulative family count

class name count
Streptomycetaceae 1

KEGG BRITE br08003 External link 512

Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		figure
C00018684 External link 512 BNP
/ NSC 64266
/ Bovinocidin
/ Hiptagenic acid
/ 3-Nitro-propionic acid
CHEMBL451226
C015392
17 / 22 / 27 0 / 14

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018684 1 / 0
P02545 Prelamin-A/C Unclassified protein C00018684 11 / 10
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018684 0 / 1
P54132 Bloom syndrome protein Enzyme C00018684 1 / 2
P68871 Hemoglobin subunit beta Secreted protein C00018684 4 / 4
Q16665 Hypoxia-inducible factor 1-alpha Transcription Factor C00018684 0 / 0
O75496 Geminin Unclassified protein C00018684 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00018684 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018684 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018684 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018684 0 / 1
Q9UNA4 DNA polymerase iota Enzyme C00018684 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00018684 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00018684 0 / 0
O00255 Menin Unclassified protein C00018684 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00018684 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00018684 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (22)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#613985 Beta-thalassemia P68871
#603902 Beta-thalassemia, dominant inclusion body type P68871
#210900 Bloom syndrome; blm P54132
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#610140 Heart-hand syndrome, slovenian type P02545
#140700 Heinz body anemias P68871
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#145000 Hyperparathyroidism 1; hrpt1 O00255
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#275210 Restrictive dermopathy, lethal P02545
#603903 Sickle cell anemia P68871

KEGG DISEASE (27)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00094 DNA repair defects P54132 (related)
H00296 Defects in RecQ helicases P54132 (related)
H00228 Thalassemia P68871 (related)
H00229 Sickle cell anemia (SCA) P68871 (related)
H00020 Colorectal cancer P68871 (marker)
H00022 Bladder cancer P68871 (marker)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)

Diseases related to CTD interactions

14 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D003072 Cognition Disorders C00018684
D004195 Disease Models, Animal C00018684
D004409 Dyskinesia, Drug-Induced C00018684
D004421 Dystonia C00018684
D034381 Hearing Loss C00018684
D006816 Huntington Disease C00018684
D006948 Hyperkinesis C00018684
D008569 Memory Disorders C00018684
D009069 Movement Disorders C00018684
D009410 Nerve Degeneration C00018684
D009422 Nervous System Diseases C00018684
D019636 Neurodegenerative Diseases C00018684
D020258 Neurotoxicity Syndromes C00018684
D015431 Weight Loss C00018684