KCF-S cluster No. 83 (53 metabolites)

• Index
• Plant Species
• KEGG BRITE br08003
• Metabolite list (53)
• Human Protein
  / Gene in interactions
• Related Diseases

Plant Species

---

Cumulative plant class count

class name	count
asterids	77

---

Cumulative family count

class name	count
Lamiaceae	77

KEGG BRITE br08003

---

Categories (0)

br08003 Category	# of metabolite

---

metabolites link (0)

br08003 Category	KEGG ID	KNApSAcK ID

Metabolite list (53)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00031075	Ponicidin	CHEMBL401207	C090365
C00031959	Lasiodonin
C00033270	Oridonin	CHEMBL454570 CHEMBL1164920 CHEMBL1434305 CHEMBL1603292 CHEMBL1971982 CHEMBL1980693 CHEMBL1994242 CHEMBL2165229	C011959	11 / 18 / 46	3 / 0
C00034653	Rabdoternin F	CHEMBL252115
C00035517	Adenolin B
C00035598	Effusanin E
C00037093	Enanderianin C / Xerophilusin H	CHEMBL415377 CHEMBL483120 CHEMBL1641893
C00037094	Enanderinanin B / (-)-Enanderinanin B
C00037429	Longikaurin B	CHEMBL400142 CHEMBL1727091 CHEMBL1987440		15 / 18 / 13
C00037430	Longikaurin D	CHEMBL252105
C00037431	Longikaurin F
C00037458	Macrocalin B	CHEMBL401208	C045862
C00037750	Rosthorin A / 3-Deoxyxerophilusin IX	CHEMBL399104
C00037816	Shikokianin		C116235
C00038020	Xerophilusin A / (-)-Xerophilusin A	CHEMBL404203
C00038021	Xerophilusin G / (-)-Xerophilusin G	CHEMBL249840
C00038022	Xerophilusin I / (-)-Xerophilusin I	CHEMBL252924
C00038023	Xerophilusin J / (-)-Xerophilusin J	CHEMBL1802178
C00038024	Xerophilusin K / (-)-Xerophilusin K	CHEMBL400256
C00039084	Effusanin C	CHEMBL415377 CHEMBL483120 CHEMBL1641893
C00039085	Effusanin D	CHEMBL521396
C00039343	Hebeirubescensin G	CHEMBL400340 CHEMBL252114
C00039344	Hebeirubescensin H	CHEMBL400340 CHEMBL252114
C00039604	Lasiokaurin	CHEMBL521234	C011893
C00039639	Longikaurin C	CHEMBL519320
C00039734	Maoecrystal I	CHEMBL253333
C00039739	Megathyrin A	CHEMBL488130
C00040141	Rabdoternin E	CHEMBL252115
C00040682	Xerophilusin B	CHEMBL400341
C00040683	Xerophilusin D / (-)-Xerophilusin D	CHEMBL252120
C00040686	Xerophilusin III / (-)-Xerophilusin III	CHEMBL481065
C00040687	Xerophilusin IV / (-)-Xerophilusin IV	CHEMBL251231
C00040688	Xerophilusin IX / (-)-Xerophilusin IX
C00040689	Xerophilusin N / (-)-Xerophilusin N	CHEMBL402260
C00040691	Xerophilusin VI / (-)-Xerophilusin VI	CHEMBL411021
C00040692	Xerophilusin VII / (-)-Xerophilusin VII
C00040693	Xerophilusin VIII / (-)-Xerophilusin VIII
C00040696	Xerophilusin XII / (-)-Xerophilusin XII	CHEMBL399079
C00040697	Xerophilusin XIII / (-)-Xerophilusin XIII	CHEMBL399080
C00041513	Effusanin A	CHEMBL252924
C00041514	Effusanin B	CHEMBL1641880
C00041724	Parvifoline C / (-)-Parvifoline C	CHEMBL520422
C00041725	Parvifoline D / (-)-Parvifoline D	CHEMBL481065
C00041726	Parvifoline E / (-)-Parvifoline E
C00041729	Parvifoline H / (-)-Parvifoline H	CHEMBL526846
C00041730	Parvifoline I / (-)-Parvifoline I	CHEMBL498440
C00041800	Rabdoternin G / (-)-Rabdoternin G
C00041911	Taibaihenryiin A	CHEMBL526846
C00043502	Excisanin H	CHEMBL518602
C00044153	Enanderianin A / (-)-Enanderianin A	CHEMBL482707
C00045386	Pseudoirroratin A / (-)-Pseudoirroratin A	CHEMBL517614
C00048471	Longikaurin E	CHEMBL1802177
C00048539	Sinuolatin B / (-)-Sinuolatin B

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P11473	Vitamin D3 receptor	NR1I1	C00033270 C00037429	2 / 3
P11021	78 kDa glucose-regulated protein	Unclassified protein	C00033270	0 / 0
Q16637	Survival motor neuron protein	Unclassified protein	C00033270	4 / 1
Q99700	Ataxin-2	Unclassified protein	C00037429	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00037429	2 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00033270	0 / 0
P04637	Cellular tumor antigen p53	Transcription Factor	C00033270	7 / 37
P00352	Retinal dehydrogenase 1	Enzyme	C00033270	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00037429	2 / 0
O75496	Geminin	Unclassified protein	C00037429	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00037429	0 / 0
P63092	Guanine nucleotide-binding protein G(s) subunit alpha isoforms short	Other membrane protein	C00037429	7 / 3
Q9NR96	Toll-like receptor 9	Toll-like and Il-1 receptors	C00037429	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00033270	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00033270	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00033270	2 / 2
O75164	Lysine-specific demethylase 4A	Enzyme	C00037429	0 / 0
Q16236	Nuclear factor erythroid 2-related factor 2	Unclassified protein	C00037429	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00033270	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00033270	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00037429	1 / 0
P01215	Glycoprotein hormones alpha chain	Unclassified protein	C00037429	0 / 3
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00037429	2 / 1
Q06710	Paired box protein Pax-8	Unclassified protein	C00037429	1 / 2
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00037429	1 / 1

3 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
596	BCL2, Bcl-2, PPP1R50	B-cell CLL/lymphoma 2	C00033270
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00033270
142	PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1	poly (ADP-ribose) polymerase 1 (EC:2.4.2.30)	C00033270

Related Diseases

Diseases related to proteins in ChEMBL interactions