PCIDB

KNApSAcK Metabolite C00037429

Metabolite

KNApSAcK Entry

id C00037429
Name Longikaurin B
CAS RN 75207-66-8
Standard InChI InChI=1S/C22H30O7/c1-11-13-5-6-14-20-8-4-7-19(3,9-28-12(2)23)15(20)18(26)22(27,29-10-20)21(14,16(11)24)17(13)25/h13-15,17-18,25-27H,1,4-10H2,2-3H3/t13-,14-,15+,17?,18-,19-,20+,21-,22+/m0/s1
Standard InChI (Main Layer) InChI=1S/C22H30O7/c1-11-13-5-6-14-20-8-4-7-19(3,9-28-12(2)23)15(20)18(26)22(27,29-10-20)21(14,16(11)24)17(13)25/h13-15,17-18,25-27H,1,4-10H2,2-3H3

Cluster

Phytochemical cluster
KCF-S cluster No. 83

Link

ChEMBL

By standard InChI
By standard InChI Main Layer CHEMBL400142 CHEMBL1727091 CHEMBL1987440

KEGG

By LinkDB

CTD

By CAS RN

Human Protein / Gene in interaction

15 ChEMBL Protein in interactions

accession description class description compound assay ID (# of activities) # of diseases
(OMIM / KEGG)
Q9NR96 Toll-like receptor 9 Toll-like and Il-1 receptors CHEMBL1727091 CHEMBL1794460 (1)
0 / 0
Q99700 Ataxin-2 Unclassified protein CHEMBL1727091 CHEMBL2114784 (1)
1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein CHEMBL1727091 CHEMBL1794499 (1)
2 / 0
P11473 Vitamin D3 receptor NR1I1 CHEMBL1727091 CHEMBL1794311 (1)
2 / 3
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein CHEMBL1727091 CHEMBL1794584 (1)
2 / 0
O75496 Geminin Unclassified protein CHEMBL1727091 CHEMBL2114843 (1) CHEMBL2114780 (1)
0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor CHEMBL1727091 CHEMBL2114788 (1)
0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein CHEMBL1727091 CHEMBL2114817 (1)
7 / 3
O75164 Lysine-specific demethylase 4A Enzyme CHEMBL1727091 CHEMBL1737991 (1)
0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein CHEMBL1727091 CHEMBL1738184 (1)
0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme CHEMBL1727091 CHEMBL2354311 (1)
1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein CHEMBL1727091 CHEMBL2114913 (1)
0 / 3
Q14191 Werner syndrome ATP-dependent helicase Enzyme CHEMBL1727091 CHEMBL2114796 (1)
2 / 1
Q06710 Paired box protein Pax-8 Unclassified protein CHEMBL1727091 CHEMBL2354301 (1)
1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein CHEMBL1727091 CHEMBL2354287 (1)
1 / 1

Related Disease

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
Q14191
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191

KEGG DISEASE (13)

KEGG disease name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
Q06710 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00032 Thyroid cancer Q06710 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)