Species

KNApSAcK Entry

Organism name Isodon japonicus
Genus Isodon
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Isodon japonicus
Linked NCBI taxonomy ID 425908
Linked level species

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (11)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00039085 External link 512 Effusanin D
CHEMBL521396
No. 83
C00037429 External link 512 Longikaurin B
CHEMBL400142
CHEMBL1727091
CHEMBL1987440
15 / 18 / 13 No. 83
C00037430 External link 512 Longikaurin D
CHEMBL252105
No. 83
C00039084 External link 512 Effusanin C
CHEMBL415377
CHEMBL483120
CHEMBL1641893
No. 83
C00039639 External link 512 Longikaurin C
CHEMBL519320
No. 83
C00039739 External link 512 Megathyrin A
CHEMBL488130
No. 83
C00039604 External link 512 Lasiokaurin
CHEMBL521234
C011893
No. 83
C00003443 External link 512 Isodonal
CHEMBL453800
No. 241 No. 41
C00039656 External link 512 Loxothyrin A
CHEMBL486708
No. 241 No. 41
C00039197 External link 512 Excisanin B
CHEMBL470766
CHEMBL2005542
No. 289 No. 41
C00040098 External link 512 Pseurata C
CHEMBL483119
No. 289 No. 41

Human Protein / Gene in interactions

15 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9NR96 Toll-like receptor 9 Toll-like and Il-1 receptors C00037429 0 / 0
Q99700 Ataxin-2 Unclassified protein C00037429 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00037429 2 / 0
P11473 Vitamin D3 receptor NR1I1 C00037429 2 / 3
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00037429 2 / 0
O75496 Geminin Unclassified protein C00037429 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00037429 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00037429 7 / 3
O75164 Lysine-specific demethylase 4A Enzyme C00037429 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00037429 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00037429 1 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00037429 0 / 3
Q14191 Werner syndrome ATP-dependent helicase Enzyme C00037429 2 / 1
Q06710 Paired box protein Pax-8 Unclassified protein C00037429 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00037429 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#114500 Colorectal cancer; crc P84022
Q14191
#137800 Glioma susceptibility 1; glm1 O75874
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#174800 Mccune-albright syndrome; mas P63092
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#277700 Werner syndrome; wrn Q14191

KEGG DISEASE (13)

KEGG name UniProt
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
Q06710 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00032 Thyroid cancer Q06710 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00296 Defects in RecQ helicases Q14191 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)