KCF-S cluster No. 8306 (1 metabolites)

Corresponding Phytochemical cluster No. 36


Plant Species


Cumulative plant class count

class name count
asterids 3

Cumulative family count

class name count
Rubiaceae 3

KEGG BRITE br08003 External link 512


Categories (1)

br08003 Category # of metabolite
Iridoids 1

metabolites link (1)

br08003 Category KEGG ID KNApSAcK ID
Iridoids C09780 C00000321

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00000321 External link 512 Genipin
CHEMBL459016
CHEMBL1317787
C007834
6 / 3 / 2 3 / 1

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q99700 Ataxin-2 Unclassified protein C00000321 1 / 1
P60033 CD81 antigen Unclassified protein C00000321 1 / 1
O75496 Geminin Unclassified protein C00000321 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000321 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00000321 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00000321 0 / 0

3 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
581 BAX, BCL2L4 BCL2-associated X protein C00000321
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00000321
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00000321

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#137800 Glioma susceptibility 1; glm1 O75874
#613496 Immunodeficiency, common variable, 6; cvid6 P60033
#183090 Spinocerebellar ataxia 2; sca2 Q99700

KEGG DISEASE (2)

KEGG name UniProt
H00088 Common variable immunodeficiency (CVID) P60033 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)

Diseases related to CTD interactions

1 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D002779 Cholestasis C00000321