KNApSAcK Metabolite C00000321
Metabolite
KNApSAcK Entry
| id | C00000321 |
|---|---|
| Name | Genipin |
| CAS RN | 6902-77-8 |
| Standard InChI | InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3 |
| Standard InChI (Main Layer) | InChI=1S/C11H14O5/c1-15-10(13)8-5-16-11(14)9-6(4-12)2-3-7(8)9/h2,5,7,9,11-12,14H,3-4H2,1H3 |
Cluster
| Phytochemical cluster | No. 36 |
|---|---|
| KCF-S cluster | No. 8306 |
Link
ChEMBL
| By standard InChI | |
|---|---|
| By standard InChI Main Layer | CHEMBL459016 CHEMBL1317787 |
KEGG
| By LinkDB | C09780 |
|---|
CTD
| By CAS RN | C007834 |
|---|
Species
Summary
List (3)
* NCBI
| KNApSAcK organism | *ID | *family | *plant class | *kingdom |
|---|---|---|---|---|
| Gardenia jasminoides | 114476 | Rubiaceae | asterids | Viridiplantae |
| Genipa americana | 58486 | Rubiaceae | asterids | Viridiplantae |
| Rothmannia globosa | 1237791 | Rubiaceae | asterids | Viridiplantae |
Human Protein / Gene in interaction
6 ChEMBL Protein in interactions
| accession | description | class description | compound | assay ID (# of activities) |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|---|
| Q99700 | Ataxin-2 | Unclassified protein | CHEMBL1317787 |
CHEMBL2114784
(1)
|
1 / 1 |
| P60033 | CD81 antigen | Unclassified protein | CHEMBL459016 |
CHEMBL1099753
(1)
|
1 / 1 |
| O75496 | Geminin | Unclassified protein | CHEMBL1317787 |
CHEMBL2114843
(1)
|
0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | CHEMBL1317787 |
CHEMBL1794401
(1)
|
0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | CHEMBL1317787 |
CHEMBL2354311
(1)
|
1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | CHEMBL1317787 |
CHEMBL1963966
(1)
|
0 / 0 |
CTD interaction (3)
| compound | gene | gene name | gene description | interaction | interaction type | form |
reference
pmid |
|---|---|---|---|---|---|---|---|
| C007834 | 581 |
BAX
BCL2L4 |
BCL2-associated X protein | genipin results in increased expression of BAX mRNA |
increases expression
|
mRNA |
22245672
|
| C007834 | 596 |
BCL2
Bcl-2 PPP1R50 |
B-cell CLL/lymphoma 2 | genipin results in decreased expression of BCL2 mRNA |
decreases expression
|
mRNA |
22245672
|
| C007834 | 836 |
CASP3
CPP32 CPP32B SCA-1 |
caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) | genipin results in increased activity of CASP3 protein |
increases activity
|
protein |
22245672
|