Rothmannia globosa
Species
KNApSAcK Entry
| Organism name | Rothmannia globosa |
|---|---|
| Genus | Rothmannia |
| Family | Rubiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Rothmannia globosa |
|---|---|
| Linked NCBI taxonomy ID | 1237791 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Rubiaceae |
|---|---|
| ID | 24966 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Metabolite list (7)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003081
|
Gardenoside
|
CHEMBL485798
CHEMBL1079679 CHEMBL1482711 CHEMBL2133850 |
C056587
|
14 / 2 / 5 | No. 56 | No. 36 |
|
|
|
C00010630
|
Mussaenoside
|
CHEMBL2355776
|
1 / 1 / 1 | No. 56 | No. 36 |
|
||
|
C00000320
|
Geniposide
|
CHEMBL462894
CHEMBL1417490 CHEMBL1718933 |
C007835
|
3 / 2 / 3 | 3 / 0 | No. 100 | No. 36 |
|
|
C00003097
|
Feretoside
/ Scandoside methyl ester / 6beta-Hydroxygeniposide |
CHEMBL463096
CHEMBL516850 |
No. 100 | No. 36 |
|
|||
|
C00040898
|
beta-Gardiol
/ (+)-beta-Gardiol |
No. 2226 |
|
|||||
|
C00040869
|
alpha-Gardiol
/ (+)-alpha-Gardiol |
No. 2226 |
|
|||||
|
C00000321
|
Genipin
|
CHEMBL459016
CHEMBL1317787 |
C007834
|
6 / 3 / 2 | 3 / 1 | No. 8306 | No. 36 |
|
Human Protein / Gene in interactions
21 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| O75496 | Geminin | Unclassified protein | C00000320 C00000321 C00003081 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00000321 C00003081 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00000320 | 0 / 0 |
| Q9GZU7 | Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 | Enzyme | C00003081 | 0 / 0 |
| P60033 | CD81 antigen | Unclassified protein | C00000321 | 1 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00000320 | 2 / 3 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00003081 | 0 / 0 |
| Q9UIF8 | Bromodomain adjacent to zinc finger domain protein 2B | Unclassified protein | C00003081 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00003081 | 1 / 1 |
| Q99700 | Ataxin-2 | Unclassified protein | C00000321 | 1 / 1 |
| P06746 | DNA polymerase beta | Enzyme | C00003081 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003081 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00003081 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00003081 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00003081 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00000321 | 1 / 0 |
| Q8IUX4 | DNA dC->dU-editing enzyme APOBEC-3F | Enzyme | C00000321 | 0 / 0 |
| Q13951 | Core-binding factor subunit beta | Unclassified protein | C00003081 | 0 / 1 |
| Q01196 | Runt-related transcription factor 1 | Unclassified protein | C00003081 | 1 / 4 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00003081 | 0 / 0 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00010630 | 1 / 1 |
3 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 581 | BAX, BCL2L4 | BCL2-associated X protein |
C00000320
C00000321
|
| 596 | BCL2, Bcl-2, PPP1R50 | B-cell CLL/lymphoma 2 |
C00000320
C00000321
|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00000320
C00000321
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #613496 | Immunodeficiency, common variable, 6; cvid6 |
P60033
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #601399 | Platelet disorder, familial, with associated myeloid malignancy |
Q01196
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00088 | Common variable immunodeficiency (CVID) |
P60033
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q01196
(related)
Q01196 (marker) |
| H00003 | Acute myeloid leukemia (AML) |
Q01196
(related)
Q01196 (marker) Q13951 (marker) |
| H00004 | Chronic myeloid leukemia (CML) |
Q01196
(related)
|
| H00978 | Thrombocytopenia (THC) |
Q01196
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|