Plant Species


Cumulative plant class count

class name count
rosids 1
eudicotyledons 1

Cumulative family count

class name count
Brassicaceae 1
Enterobacteriaceae 1
Crassulaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00001192 External link 512 L-Malic acid
/ L-(-)-Malic acid
CHEMBL225986
CHEMBL1455497
12 / 9 / 8

Human Protein / Gene in interactions

12 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00001192 1 / 0
Q16637 Survival motor neuron protein Unclassified protein C00001192 4 / 1
Q9UIF8 Bromodomain adjacent to zinc finger domain protein 2B Unclassified protein C00001192 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00001192 0 / 1
Q9GZT9 Egl nine homolog 1 Enzyme C00001192 1 / 1
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00001192 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00001192 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00001192 0 / 1
O75164 Lysine-specific demethylase 4A Enzyme C00001192 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00001192 0 / 0
Q9C0B1 Alpha-ketoglutarate-dependent dioxygenase FTO Unclassified protein C00001192 1 / 2
Q13148 TAR DNA-binding protein 43 Unclassified protein C00001192 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (9)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#609820 Erythrocytosis, familial, 3; ecyt3 Q9GZT9
#612938 Growth retardation, developmental delay, coarse facies, and early death; gdfd Q9C0B1
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637

KEGG DISEASE (8)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00409 Type II diabetes mellitus Q9C0B1 (related)
H00926 Growth retardation, developmental delay, coarse facies, and early death Q9C0B1 (related)
H00236 Congenital polycythemia Q9GZT9 (related)