PCIDB

KCF-S cluster No. 8919 (1 metabolites)

class name	count

class name	count
Amanitaceae	2

br08003 Category	# of metabolite

br08003 Category	KEGG ID	KNApSAcK ID

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	figure
C00002345	Ibotenic acid	CHEMBL284895 CHEMBL30285	D007051	19 / 18 / 23	0 / 7

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00002345	1 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00002345	0 / 0
P21728	D(1A) dopamine receptor	Dopamine receptor	C00002345	0 / 0
P02545	Prelamin-A/C	Unclassified protein	C00002345	11 / 10
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00002345	0 / 1
Q14416	Metabotropic glutamate receptor 2	Metabotropic glutamate receptor	C00002345	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00002345	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00002345	0 / 0
Q14833	Metabotropic glutamate receptor 4	Metabotropic glutamate receptor	C00002345	0 / 0
Q13255	Metabotropic glutamate receptor 1	Metabotropic glutamate receptor	C00002345	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00002345	1 / 1
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00002345	0 / 1
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00002345	0 / 0
P41594	Metabotropic glutamate receptor 5	Metabotropic glutamate receptor	C00002345	0 / 0
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00002345	0 / 0
O00255	Menin	Unclassified protein	C00002345	2 / 5
Q03164	Histone-lysine N-methyltransferase 2A	Enzyme	C00002345	1 / 2
Q13951	Core-binding factor subunit beta	Unclassified protein	C00002345	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00002345	1 / 4

OMIM	preferred title	UniProt
#115200	Cardiomyopathy, dilated, 1a; cmd1a	P02545
#212112	Cardiomyopathy, dilated, with hypergonadotropic hypogonadism	P02545
#605588	Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1	P02545
#609535	Drug metabolism, poor, cyp2c19-related	P33261
#608902	Drug metabolism, poor, cyp2d6-related	P10635
#181350	Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2	P02545
#605130	Hairy elbows, short stature, facial dysmorphism, and developmental delay	Q03164
#610140	Heart-hand syndrome, slovenian type	P02545
#176670	Hutchinson-gilford progeria syndrome; hgps	P02545
#145000	Hyperparathyroidism 1; hrpt1	O00255
#151660	Lipodystrophy, familial partial, type 2; fpld2	P02545
#248370	Mandibuloacral dysplasia with type a lipodystrophy; mada	P02545
#131100	Multiple endocrine neoplasia, type i; men1	O00255
#613205	Muscular dystrophy, congenital, lmna-related	P02545
#159001	Muscular dystrophy, limb-girdle, type 1b; lgmd1b	P02545
#601399	Platelet disorder, familial, with associated myeloid malignancy	Q01196
#275210	Restrictive dermopathy, lethal	P02545
#614831	Spinocerebellar ataxia, autosomal recessive 13; scar13	Q13255

KEGG	name	UniProt
H00033	Adrenal carcinoma	O00255 (related)
H00034	Carcinoid	O00255 (related)
H00045	Malignant islet cell carcinoma	O00255 (related)
H00246	Primary hyperparathyroidism	O00255 (related)
H01102	Pituitary adenomas	O00255 (related)
H00264	Charcot-Marie-Tooth disease (CMT)	P02545 (related)
H00294	Dilated cardiomyopathy (DCM)	P02545 (related)
H00420	Familial partial lipodystrophy (FPL)	P02545 (related)
H00563	Emery-Dreifuss muscular dystrophy	P02545 (related)
H00590	Congenital muscular dystrophies (CMD/MDC)	P02545 (related)
H00593	Limb-girdle muscular dystrophy (LGMD)	P02545 (related)
H00601	Hutchinson-Gilford progeria syndrome	P02545 (related)
H00663	Restrictive dermopathy	P02545 (related)
H00665	Mandibuloacral dysplasia	P02545 (related)
H01216	Left ventricular noncompaction (LVNC)	P02545 (related)
H00036	Osteosarcoma	P08684 (marker)
H01205	Coumarin resistance	P11712 (related)
H01171	Poor drug metabolism (PM)	P33261 (related)
H00001	Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia)	Q01196 (related) Q01196 (marker) Q03164 (related) Q03164 (marker)
H00003	Acute myeloid leukemia (AML)	Q01196 (related) Q01196 (marker) Q13951 (marker)
H00004	Chronic myeloid leukemia (CML)	Q01196 (related)
H00978	Thrombocytopenia (THC)	Q01196 (related)
H00002	Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)	Q03164 (related)