Plant Species


Cumulative plant class count

class name count
rosids 1

Cumulative family count

class name count
Brassicaceae 1

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (1)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00007267 External link 512 Ammonia
CHEMBL1160819
CHEMBL1201189
D000641
4 / 5 / 2 11 / 13

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10828 Thyroid hormone receptor beta NR1A2 C00007267 3 / 1
P17787 Neuronal acetylcholine receptor subunit beta-2 CHRN beta C00007267 1 / 1
P43681 Neuronal acetylcholine receptor subunit alpha-4 CHRN alpha C00007267 1 / 1
P36544 Neuronal acetylcholine receptor subunit alpha-7 CHRN alpha C00007267 0 / 0

11 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
8639 AOC3, HPAO, SSAO, VAP-1, VAP1 amine oxidase, copper containing 3 (EC:1.4.3.21) C00007267
361 AQP4, HMIWC2, MIWC aquaporin 4 C00007267
2593 GAMT, CCDS2, PIG2, TP53I2 guanidinoacetate N-methyltransferase (EC:2.1.1.2) C00007267
2628 GATM, AGAT, AT, CCDS3 glycine amidinotransferase (L-arginine:glycine amidinotransferase) (EC:2.1.4.1) C00007267
2670 GFAP glial fibrillary acidic protein C00007267
2752 GLUL, GLNS, GS, PIG43, PIG59 glutamate-ammonia ligase (EC:4.1.1.15 6.3.1.2) C00007267
3162 HMOX1, HMOX1D, HO-1, HSP32, bK286B10 heme oxygenase (decycling) 1 (EC:1.14.99.3) C00007267
3553 IL1B, IL-1, IL1-BETA, IL1F2 interleukin 1, beta C00007267
4843 NOS2, HEP-NOS, INOS, NOS, NOS2A nitric oxide synthase 2, inducible (EC:1.14.13.39) C00007267
51458 RHCG, C15orf6, PDRC2, RHGK, SLC42A3 Rh family, C glycoprotein C00007267
6535 SLC6A8, CCDS1, CRT, CRTR, CT1 solute carrier family 6 (neurotransmitter transporter), member 8 C00007267

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (5)

OMIM preferred title UniProt
#600513 Epilepsy, nocturnal frontal lobe, 1; enfl1 P43681
#605375 Epilepsy, nocturnal frontal lobe, 3; enfl3 P17787
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (2)

KEGG name UniProt
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00807 Autosomal dominant nocturnal frontal lobe epilepsy (ADNFLE) P17787 (related)
P43681 (related)

Diseases related to CTD interactions

13 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D001238 Asphyxia Neonatorum C00007267
D001928 Brain Diseases, Metabolic C00007267
D001929 Brain Edema C00007267
D002318 Cardiovascular Diseases C00007267
D002493 Central Nervous System Diseases C00007267
D017449 Dermatitis, Allergic Contact C00007267
D006970 Disorders of Excessive Somnolence C00007267
D005756 Gastritis C00007267
D006501 Hepatic Encephalopathy C00007267
D009336 Necrosis C00007267
D011041 Poisoning C00007267
D012640 Seizures C00007267
D013226 Status Epilepticus C00007267