KCF-S cluster No. 8946 (1 metabolites)
Plant Species
Cumulative plant class count
| class name | count |
|---|---|
| rosids | 1 |
Cumulative family count
| class name | count |
|---|---|
| Brassicaceae | 1 |
KEGG BRITE br08003
Categories (0)
| br08003 Category | # of metabolite |
|---|
metabolites link (0)
| br08003 Category | KEGG ID | KNApSAcK ID |
|---|
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
figure |
|---|---|---|---|---|---|---|
|
C00007314
|
Urea
|
CHEMBL985
CHEMBL2096635 CHEMBL2096648 |
D014508
|
7 / 12 / 11 | 12 / 6 |
|
Human Protein / Gene in interactions
7 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q03181 | Peroxisome proliferator-activated receptor delta | NR1C2 | C00007314 | 0 / 0 |
| P02545 | Prelamin-A/C | Unclassified protein | C00007314 | 11 / 10 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00007314 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00007314 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00007314 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00007314 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00007314 | 1 / 1 |
12 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 174 | AFP, FETA, HPAFP | alpha-fetoprotein |
C00007314
|
| 213 | ALB, PRO0883, PRO0903, PRO1341 | albumin |
C00007314
|
| 89872 | AQP10, AQPA_HUMAN | aquaporin 10 |
C00007314
|
| 384 | ARG2 | arginase 2 (EC:3.5.3.1) |
C00007314
|
| 567 | B2M | beta-2-microglobulin |
C00007314
|
| 1374 | CPT1A, CPT1, CPT1-L, L-CPT1 | carnitine palmitoyltransferase 1A (liver) (EC:2.3.1.21) |
C00007314
|
| 2260 | FGFR1, BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, HH2, HRTFDS, KAL2, N-SAM, OGD, bFGF-R-1 | fibroblast growth factor receptor 1 (EC:2.7.10.1) |
C00007314
|
| 3162 | HMOX1, HMOX1D, HO-1, HSP32, bK286B10 | heme oxygenase (decycling) 1 (EC:1.14.99.3) |
C00007314
|
| 3791 | KDR, CD309, FLK1, VEGFR, VEGFR2 | kinase insert domain receptor (a type III receptor tyrosine kinase) (EC:2.7.10.1) |
C00007314
|
| 5465 | PPARA, NR1C1, PPAR, PPARalpha, hPPAR | peroxisome proliferator-activated receptor alpha |
C00007314
|
| 6648 | SOD2, IPOB, MNSOD, MVCD6 | superoxide dismutase 2, mitochondrial (EC:1.15.1.1) |
C00007314
|
| 7276 | TTR, CTS, CTS1, HsT2651, PALB, TBPA | transthyretin |
C00007314
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
KEGG DISEASE (11)
| KEGG | name | UniProt |
|---|---|---|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|