Plant Species


Cumulative plant class count

class name count

Cumulative family count

class name count
Streptomycetaceae 10

KEGG BRITE br08003 External link 512


Categories (0)

br08003 Category # of metabolite

metabolites link (0)

br08003 Category KEGG ID KNApSAcK ID

Metabolite list (10)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
figure
C00016617 External link 512 YF 044P-D
C088534
C00017793 External link 512 WK 142A
C00017794 External link 512 Ahpatinin F
/ Pepstatin A
C00017795 External link 512 WK 142B
C00017969 External link 512 Butyl pepstatin
/ 1-[N-(1-Oxobutyl)-L-valine]-pepstatin A
C00017971 External link 512 Hydroxypepstatin A
/ 4-L-Serine-pepstatin A
C013049
C00018785 External link 512 Pepstatin
/ NSC 272671
/ Ahpatinin C
/ Pepstatin A
/ Procidin S 735A
/ Pepsin inhibitor S 735A
CHEMBL38526
CHEMBL296588
CHEMBL74864
CHEMBL263246
CHEMBL94014
CHEMBL122642
CHEMBL1478188
25 / 26 / 27
C00018845 External link 512 Pepstatin B
C00018846 External link 512 Pepstatin C
C00018847 External link 512 Pepstanone A
C003067

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00018785 1 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00018785 2 / 0
Q99895 Chymotrypsin-C S1A C00018785 0 / 2
P02545 Prelamin-A/C Unclassified protein C00018785 11 / 10
P10828 Thyroid hormone receptor beta NR1A2 C00018785 3 / 1
P09668 Pro-cathepsin H C1A C00018785 0 / 1
P0DJD9 Pepsin A-5 A1A C00018785 0 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00018785 0 / 1
P11473 Vitamin D3 receptor NR1I1 C00018785 2 / 3
P07858 Cathepsin B C1A C00018785 0 / 1
P14091 Cathepsin E A1A C00018785 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00018785 0 / 0
O75496 Geminin Unclassified protein C00018785 0 / 0
P07339 Cathepsin D A1A C00018785 1 / 2
P07711 Cathepsin L1 C1A C00018785 0 / 0
P00797 Renin A1A C00018785 2 / 2
Q13443 Disintegrin and metalloproteinase domain-containing protein 9 M12B C00018785 1 / 1
P56817 Beta-secretase 1 A1A C00018785 0 / 0
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00018785 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00018785 1 / 1
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00018785 0 / 1
P46063 ATP-dependent DNA helicase Q1 Enzyme C00018785 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00018785 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00018785 1 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00018785 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (26)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#610127 Ceroid lipofuscinosis, neuronal, 10; cln10 P07339
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#612775 Cone-rod dystrophy 9; cord9 Q13443
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#613092 Hyperuricemic nephropathy, familial juvenile, 2; hnfj2 P00797
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#267430 Renal tubular dysgenesis; rtd P00797
#275210 Restrictive dermopathy, lethal P02545
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (27)

KEGG name UniProt
H00541 Uromodulin-associated kidney diseases P00797 (related)
H00575 Renal tubular dysgenesis P00797 (related)
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00149 Neuronal ceroid lipofuscinosis P07339 (related)
H00810 Progressive myoclonic epilepsy (PME) P07339 (related)
H00932 Tropical calcific pancreatitis P07858 (related)
Q99895 (related)
H00036 Osteosarcoma P08684 (marker)
H00408 Type I diabetes mellitus P09668 (related)
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H01205 Coumarin resistance P11712 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00481 Cone-rod dystrophy and cone dystrophy Q13443 (related)
H00933 Hereditary pancreatitis Q99895 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)