Fusarium sporotrichioides
Species
KNApSAcK Entry
| Organism name | Fusarium sporotrichioides |
|---|---|
| Genus | |
| Family | |
| Kingdom |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Fusarium sporotrichioides |
|---|---|
| Linked NCBI taxonomy ID | 5514 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Nectriaceae |
|---|---|
| ID | 110618 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
Plant class
| Plant class | |
|---|---|
| ID |
Metabolite list (15)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003647
|
Campesterol
/ 24alpha-Methylcholesterol / (24R)24-Methylcholest-5-en-3beta-ol |
CHEMBL520535
CHEMBL485421 CHEMBL1836653 |
C021273
|
No. 53 | No. 11 |
|
||
|
C00003672
|
Sitosterol
/ beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00023770
|
Sitosterol
/ Stigmasta-5,22-dien-3beta-ol / (24R)24-Ethylcholesta-5,22-dien-3beta-ol |
CHEMBL221542
CHEMBL1398443 CHEMBL1875388 |
17 / 19 / 12 | No. 53 | No. 11 |
|
||
|
C00003652
|
Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol |
CHEMBL222608
CHEMBL1232562 CHEMBL1512075 CHEMBL1741735 CHEMBL1965225 |
D004875
|
12 / 14 / 11 | No. 111 | No. 11 |
|
|
|
C00012639
|
NT 1
/ Toxin T 1 / Toxin NT 1 / Isoneosolaniol |
CHEMBL152525
CHEMBL523782 |
C032169
|
No. 539 |
|
|||
|
C00012650
|
Sporotrichiol
|
No. 539 |
|
|||||
|
C00012640
|
Toxin T 3
/ T 2 triol / Toxin T 2 triol / Deacetyl HT 2 toxin / 12,13-Epoxy-trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol 8-isovalerate |
CHEMBL152136
|
No. 539 |
|
||||
|
C00012641
|
(3alpha,4beta)-4,15-bis(Acetyloxy)-12,13-epoxy-3-hydroxytrichothec-9-en-8-one
|
CHEMBL149588
CHEMBL155135 |
No. 539 |
|
||||
|
C00012638
|
Toxin NT 2
/ 15-Deacetylneosolaniol |
CHEMBL424517
|
C032170
|
No. 1091 |
|
|||
|
C00012637
|
Toxin T 4
/ T-2 tetrol / T-2 Tetraol / T 2 toxin tetraol / Toxin T 2 tetraol / 12,13-Epoxy-trichothec-9-ene-3alpha,4beta,8alpha,15-tetrol |
CHEMBL152377
CHEMBL152639 |
C046700
|
No. 1091 |
|
|||
|
C00012625
|
8beta-Hydroxysambucoin
|
CHEMBL518270
CHEMBL478958 |
No. 3124 |
|
||||
|
C00012624
|
8alpha-Hydroxysambucoin
|
CHEMBL518270
CHEMBL478958 |
No. 3124 |
|
||||
|
C00012655
|
Trichotriol
/ [3S-[3lphaa,4beta,5beta,7beta(1R*,4S*)]]-7-(4-Hydroxy-1,4-dimethyl-2-cyclohexen-1-yl)-7-methyl-1-oxaspiro[2.4]heptane-4,5-diol |
No. 3653 |
|
|||||
|
C00012649
|
Sporol
/ [3S-(3alpha,4abeta,5aalpha,7b,8aalpha,8balpha)]-Hexahydro-3,8a-dimethyl-4a,7-Epoxy-3,8b-ethano-1H,5aH-cyclopenta[4,5]furo[3,2-c]pyran-5a-methanol |
No. 7507 |
|
|||||
|
C00012658
|
FS 2
/ Toxin FS 2 / [1S-[1alpha,4beta(1R*,4S*)]]-4-[4-Hydroxy-2-(hydroxymethyl)-1-methyl-2-cyclopenten-1-yl]-1,4-dimethyl-2-cyclohexen-1-ol |
No. 8674 |
|
Human Protein / Gene in interactions
24 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003652 C00003672 C00023770 | 1 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003652 C00003672 C00023770 | 0 / 1 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003652 C00003672 C00023770 | 1 / 1 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003652 C00003672 C00023770 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003652 C00003672 C00023770 | 0 / 1 |
| P00734 | Prothrombin | S1A | C00003672 C00023770 | 4 / 2 |
| P08183 | Multidrug resistance protein 1 | drug | C00003672 C00023770 | 1 / 0 |
| P08047 | Transcription factor Sp1 | Unclassified protein | C00003672 C00023770 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00003672 C00023770 | 1 / 1 |
| P80365 | Corticosteroid 11-beta-dehydrogenase isozyme 2 | Enzyme | C00003672 C00023770 | 1 / 1 |
| P49841 | Glycogen synthase kinase-3 beta | Gsk | C00003672 C00023770 | 0 / 0 |
| P18031 | Tyrosine-protein phosphatase non-receptor type 1 | Tyr | C00003672 C00023770 | 0 / 0 |
| P16473 | Thyrotropin receptor | Glycohormone receptor | C00003672 C00023770 | 3 / 2 |
| P14679 | Tyrosinase | Oxidoreductase | C00003672 C00023770 | 4 / 2 |
| P06746 | DNA polymerase beta | Enzyme | C00003672 C00023770 | 0 / 0 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003672 C00023770 | 2 / 0 |
| P03372 | Estrogen receptor | NR3A1 | C00003672 C00023770 | 1 / 1 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003652 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003652 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003652 | 5 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003652 | 4 / 3 |
| P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00003652 | 1 / 1 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003652 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003652 | 2 / 3 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (31)
| OMIM | preferred title | UniProt |
|---|---|---|
| #608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
| #103470 | Albinism, ocular, with sensorineural deafness |
P14679
|
| #203100 | Albinism, oculocutaneous, type ia; oca1a |
P14679
|
| #606952 | Albinism, oculocutaneous, type ib; oca1b |
P14679
|
| #218030 | Apparent mineralocorticoid excess; ame |
P80365
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #615363 | Estrogen resistance; estrr |
P03372
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #603373 | Hyperthyroidism, familial gestational |
P16473
|
| #609152 | Hyperthyroidism, nonautoimmune |
P16473
|
| #275200 | Hypothyroidism, congenital, nongoitrous, 1; chng1 |
P16473
|
| #612244 | Inflammatory bowel disease 13; ibd13 |
P08183
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #614390 | Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 |
P00734
|
| #613679 | Prothrombin deficiency, congenital |
P00734
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #601800 | Skin/hair/eye pigmentation, variation in, 3; shep3 |
P14679
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #601367 | Stroke, ischemic |
P00734
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #188050 | Thrombophilia due to thrombin defect; thph1 |
P00734
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
KEGG DISEASE (20)
| KEGG | name | UniProt |
|---|---|---|
| H00223 | Inherited thrombophilia |
P00734
(related)
|
| H01254 | Congenital prothrombin deficiency |
P00734
(related)
|
| H00026 | Endometrial Cancer |
P03372
(marker)
|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00168 | Oculocutaneous albinism (OCA) |
P14679
(related)
|
| H00038 | Malignant melanoma |
P14679
(marker)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
P16473
(related)
|
| H01269 | Congenital hyperthyroidism |
P16473
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00966 | AICA-ribosiduria |
P31939
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|
| H00259 | Apparent mineralocorticoid excess syndrome |
P80365
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|