| Organism name | Poria cocos |
|---|---|
| Genus | |
| Family | |
| Kingdom |
| Linked NCBI taxonomy name | Wolfiporia cocos |
|---|---|
| Linked NCBI taxonomy ID | 81056 |
| Linked level | species |
| Family in NCBI taxonomy | Coriolaceae |
|---|---|
| ID | 83233 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00023810
|
3-O-Acetyltumulosic acid
|
CHEMBL468034
|
C102487
|
No. 86 | No. 51 |
|
||
|
C00047651
|
25-Hydroxy-3-epitumulosic acid
/ (+)-25-Hydroxy-3-epitumulosic acid |
No. 86 | No. 51 |
|
||||
|
C00023799
|
Eburicoic acid
|
CHEMBL179188
CHEMBL1981478 |
C004867
|
0 / 1 | No. 86 | No. 51 |
|
|
|
C00047644
|
16alpha-Hydroxyeburiconic acid
|
CHEMBL1077754
|
No. 86 | No. 51 |
|
|||
|
C00023800
|
Tumulosic acid
|
CHEMBL461484
|
No. 86 | No. 51 |
|
|||
|
C00023782
|
3beta-Hydroxylanosta-7,9(11),24-trien-21-oic acid
|
CHEMBL226995
CHEMBL2203608 |
No. 91 |
|
||||
|
C00003652
|
Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol |
CHEMBL222608
CHEMBL1232562 CHEMBL1512075 CHEMBL1741735 CHEMBL1965225 |
D004875
|
12 / 14 / 11 | No. 111 | No. 11 |
|
|
|
C00023804
|
Dehydrotumulosic acid
|
CHEMBL517584
CHEMBL465312 |
C102488
|
No. 551 |
|
|||
|
C00030104
|
Dehydropachymic acid
|
CHEMBL226527
CHEMBL2203609 |
No. 551 |
|
||||
|
C00047676
|
5alpha,8alpha-Peroxydehydrotumulosic acid
/ (+)-5alpha,8alpha-Peroxydehydrotumulosic acid |
CHEMBL226575
CHEMBL1078248 |
No. 551 |
|
||||
|
C00023803
|
Dehydroeburicoic acid
|
CHEMBL1744446
|
No. 551 |
|
||||
|
C00023801
|
Polyporenic acid C
|
CHEMBL461276
|
C476268
|
No. 551 |
|
|||
|
C00045180
|
3-Epidehydrotumulosic Acid
|
CHEMBL517584
CHEMBL465312 |
No. 551 |
|
||||
|
C00044055
|
3beta-p-Hydroxybenzoyldehydrotumulosic acid
|
No. 551 |
|
|||||
|
C00043842
|
Poricoic acid H
/ (+)-Poricoic acid H |
CHEMBL251767
|
No. 562 |
|
||||
|
C00043841
|
Poricoic acid G
/ (+)-Poricoic acid G |
CHEMBL138450
|
No. 562 |
|
||||
|
C00048069
|
Poricoic acid HM
/ (-)-Poricoic acid HM |
CHEMBL1078422
|
No. 562 |
|
||||
|
C00045382
|
Poricoic acid B
|
CHEMBL456872
|
No. 562 |
|
||||
|
C00040062
|
Poricoic acid DM
/ (+)-Poricoic acid DM |
CHEMBL427415
CHEMBL1078556 |
No. 562 |
|
||||
|
C00040061
|
Poricoic acid CM
/ (+)-Poricoic acid CM |
CHEMBL374393
|
No. 562 |
|
||||
|
C00047652
|
25-Hydroxyporicoic acid C
/ (-)-25-Hydroxyporicoic acid C |
CHEMBL1078371
|
No. 562 |
|
||||
|
C00048068
|
Poricoic acid GM
/ (-)-Poricoic acid GM |
CHEMBL1079200
|
No. 562 |
|
||||
|
C00047654
|
26-Hydroxyporicoic acid DM
/ (+)-26-Hydroxyporicoic acid DM |
CHEMBL1078650
|
No. 562 |
|
||||
|
C00040060
|
Poricoic acid AM
/ (+)-Poricoic acid AM |
CHEMBL389661
CHEMBL1078179 |
No. 562 |
|
||||
|
C00047680
|
6,7-Dehydroporicoic acid H
/ (-)-6,7-Dehydroporicoic acid H |
CHEMBL1078423
|
No. 562 |
|
||||
|
C00047653
|
25-Methoxyporicoic acid A
/ (+)-25-Methoxyporicoic acid A |
CHEMBL1078640
|
No. 562 |
|
||||
|
C00045291
|
Dehydroabietic acid methyl ester
/ (+)-Dehydroabietic acid methyl ester |
CHEMBL12798
|
No. 2322 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003652 | 1 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003652 | 0 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003652 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003652 | 0 / 0 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003652 | 0 / 0 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003652 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003652 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003652 | 1 / 1 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003652 | 0 / 1 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003652 | 5 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003652 | 4 / 3 |
| P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00003652 | 1 / 1 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00966 | AICA-ribosiduria |
P31939
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|