| Organism name | Ganoderma applanatum |
|---|---|
| Genus | Ganoderma |
| Family | Ganodermataceae |
| Kingdom | Fungi |
| Linked NCBI taxonomy name | Ganoderma applanatum |
|---|---|
| Linked NCBI taxonomy ID | 29884 |
| Linked level | species |
| Family in NCBI taxonomy | Ganodermataceae |
|---|---|
| ID | 5313 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00023791
|
Alnusenone
/ Friedoolean-5-en-3-one |
CHEMBL517609
|
1 / 0 / 0 | No. 13 | No. 51 |
|
||
|
C00030354
|
Ganoderic acid AP3
/ (+)-Ganoderic acid AP3 |
No. 55 |
|
|||||
|
C00030349
|
Ganoderenic acid A
|
CHEMBL1922171
|
C118637
|
1 / 0 / 0 | No. 55 |
|
||
|
C00030350
|
Ganoderenic acid B
|
CHEMBL2205010
|
No. 55 |
|
||||
|
C00030352
|
Ganoderenic acid G
/ (+)-Ganoderenic acid G |
No. 55 |
|
|||||
|
C00030351
|
Ganoderenic acid D
|
CHEMBL1922179
|
1 / 0 / 0 | No. 55 |
|
|||
|
C00003747
|
Friedelin
/ Friedeline / Friedelanone / (-)-Friedelin / Friedelan-3-one |
CHEMBL485998
CHEMBL1551590 |
C060796
|
2 / 0 / 0 | No. 101 | No. 52 |
|
|
|
C00003652
|
Ergosterol
/ Ergosta-5,7,22-trien-3beta-ol |
CHEMBL222608
CHEMBL1232562 CHEMBL1512075 CHEMBL1741735 CHEMBL1965225 |
D004875
|
12 / 14 / 11 | No. 111 | No. 11 |
|
|
|
C00023765
|
Ergosta-7,22-dien-3-one
/ (24S)24-Methylcholesta-7,22-dien-3-one |
CHEMBL516711
CHEMBL1514671 |
C059439
|
1 / 0 / 1 | No. 111 | No. 11 |
|
|
|
C00023754
|
5,6-Dehydroergosterol
/ Ergosta-7,22-dien-3beta-ol / 24-Methylcholesta-7,22-dien-3beta-ol |
CHEMBL463973
CHEMBL560819 |
No. 111 | No. 11 |
|
|||
|
C00030353
|
Ganoderic acid AP2
/ (+)-Ganoderic acid AP2 |
No. 268 |
|
|||||
|
C00034980
|
(-)-7-Hydroxycalamenene
|
No. 824 |
|
|||||
|
C00036534
|
3alpha-Carboxyacetoxyquercinic acid
/ 3alpha-Carboxyacetoxy-24-methyl-23-oxolanost-8-en-26-oic acid |
CHEMBL448136
|
No. 1463 |
|
||||
|
C00035046
|
Applanoxidic acid E
|
No. 1849 |
|
|||||
|
C00035047
|
Applanoxidic acid F
|
No. 1849 |
|
|||||
|
C00035049
|
Applanoxidic acid H
|
No. 1849 |
|
|||||
|
C00035048
|
Applanoxidic acid G
|
CHEMBL515052
|
No. 1849 |
|
||||
|
C00030200
|
Ergosterol peroxide
/ Ergosterol 5,8-peroxide / (-)-Ergosterol 5,8-peroxide / 5alpha,8alpha-Epidioxyergosta-6,22-dien-3beta-ol / (-)-5alpha,8alpha-Epidioxyergosta-6,22-dien-3beta-ol |
CHEMBL434750
CHEMBL515808 CHEMBL1801968 CHEMBL1969254 |
C036071
|
1 / 0 / 0 | 1 / 4 | No. 2300 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| Q96RI1 | Bile acid receptor | NR1H4 | C00003747 C00030200 | 0 / 0 |
| P08684 | Cytochrome P450 3A4 | Cytochrome P450 3A4 | C00003652 C00023765 | 0 / 1 |
| P15121 | Aldose reductase | Enzyme | C00030349 C00030351 | 0 / 0 |
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003652 | 1 / 0 |
| P23219 | Prostaglandin G/H synthase 1 | Oxidoreductase | C00023791 | 0 / 0 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00003652 | 0 / 0 |
| P11712 | Cytochrome P450 2C9 | Cytochrome P450 2C9 | C00003652 | 0 / 1 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00003652 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003652 | 2 / 3 |
| P05177 | Cytochrome P450 1A2 | Cytochrome P450 1A2 | C00003652 | 0 / 0 |
| P16050 | Arachidonate 15-lipoxygenase | Enzyme | C00003652 | 0 / 0 |
| P33261 | Cytochrome P450 2C19 | Cytochrome P450 2C19 | C00003652 | 1 / 1 |
| Q8TDU6 | G-protein coupled bile acid receptor 1 | Steroid-like ligand receptor | C00003747 | 0 / 0 |
| P22309 | UDP-glucuronosyltransferase 1-1 | Enzyme | C00003652 | 5 / 1 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003652 | 4 / 3 |
| P31939 | Bifunctional purine biosynthesis protein PURH | Enzyme | C00003652 | 1 / 1 |
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 836 | CASP3, CPP32, CPP32B, SCA-1 | caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) |
C00030200
|
| OMIM | preferred title | UniProt |
|---|---|---|
| #608688 | Aicar transformylase/imp cyclohydrolase deficiency |
P31939
|
| #601816 | Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 |
P22309
|
| #218800 | Crigler-najjar syndrome, type i |
P22309
|
| #606785 | Crigler-najjar syndrome, type ii |
P22309
|
| #609535 | Drug metabolism, poor, cyp2c19-related |
P33261
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #143500 | Gilbert syndrome |
P22309
|
| #237900 | Hyperbilirubinemia, transient familial neonatal; hblrtfn |
P22309
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00036 | Osteosarcoma |
P08684
(marker)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H01205 | Coumarin resistance |
P11712
(related)
|
| H00208 | Hyperbilirubinemia |
P22309
(related)
|
| H00966 | AICA-ribosiduria |
P31939
(related)
|
| H01171 | Poor drug metabolism (PM) |
P33261
(related)
|