Larix kaempferi (Lamb.) Carr

• Index
• Plant Species
• Metabolite list (15)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Larix kaempferi (Lamb.) Carr
Genus	Larix
Family	Pinaceae
Kingdom	Plantae

---

NCBI taxonomy

Entry

Linked NCBI taxonomy name	Larix
Linked NCBI taxonomy ID	3325
Linked level	genus

Family

Family in NCBI taxonomy	Pinaceae
ID	3318

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	Spermatophyta
ID	58024

Metabolite list (15)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00023770	Sitosterol / Stigmasta-5,22-dien-3beta-ol / (24R)24-Ethylcholesta-5,22-dien-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00029821	Sitostenone / beta-Sitostenone / Stigmast-4-en-3-one / Stigmast-4-ene-3-one	CHEMBL66926				No. 53	No. 11
C00041127	Stigmastan 3,6-dione					No. 68	No. 11
C00041128	Stigmastan-3-one					No. 68	No. 11
C00003747	Friedelin / Friedeline / Friedelanone / (-)-Friedelin / Friedelan-3-one	CHEMBL485998 CHEMBL1551590	C060796	2 / 0 / 0		No. 101	No. 52
C00035217	24-Methylenecycloartanone / 3-Oxo-24-methylenecycloartane	CHEMBL376835				No. 129	No. 11
C00003661	24-Methylenecycloartanol / 24-Methylenecycloartan-3beta-ol	CHEMBL121329 CHEMBL376350	C066041			No. 129	No. 11
C00040804	24-Methylenecycloartan-3-one	CHEMBL376835				No. 129	No. 11
C00020065	alpha-Cadinol / (-)-alpha-Cadinol	CHEMBL486795				No. 205	No. 38
C00022713	Larixol	CHEMBL1370284		5 / 7 / 37		No. 256	No. 46
C00040773	16-nor-15-Oxoabieta-8,11,13-trien-18-oic acid					No. 323	No. 41
C00040763	12,15-Dihydroxyabieta-8,11,13-trien-18-oic acid					No. 323	No. 41
C00040858	Abieta-8,11,13,15-tetraen-18-oic acid					No. 323	No. 41
C00020240	Oplopanone / (-)-Oplopanone					No. 1395
C00041092	Rheosmin	CHEMBL105912	C035522	1 / 3 / 4	1 / 1	No. 5516

Human Protein / Gene in interactions

24 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00022713 C00023770	0 / 1
P00734	Prothrombin	S1A	C00023770	4 / 2
P04637	Cellular tumor antigen p53	Transcription Factor	C00022713	7 / 37
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00023770	2 / 0
P06746	DNA polymerase beta	Enzyme	C00023770	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003747	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00023770	0 / 0
P16473	Thyrotropin receptor	Glycohormone receptor	C00023770	3 / 2
P08183	Multidrug resistance protein 1	drug	C00023770	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00023770	0 / 1
P49841	Glycogen synthase kinase-3 beta	Gsk	C00023770	0 / 0
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00022713	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00023770	0 / 0
P14679	Tyrosinase	Oxidoreductase	C00023770	4 / 2
Q96RI1	Bile acid receptor	NR1H4	C00003747	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00022713	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00023770	0 / 0
P03372	Estrogen receptor	NR3A1	C00023770	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00022713	0 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00023770	1 / 1
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00023770	1 / 0
P10275	Androgen receptor	NR3C4	C00041092	3 / 4
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00023770	1 / 1
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00023770	1 / 1

1 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
367	AR, AIS, DHTR, HUMARA, HYSP1, KD, NR3C4, SBMA, SMAX1, TFM	androgen receptor	C00041092

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions