Ferula szowitsiana

• Index
• Plant Species
• Metabolite list (12)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Ferula szowitsiana
Genus	Ferula
Family	Apiaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Ferula szowitsiana
Linked NCBI taxonomy ID	555415
Linked level	species

Family

Family in NCBI taxonomy	Apiaceae
ID	4037

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (12)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00003672	Sitosterol / beta-sitosterl / (-)-beta-Sitosterol / Stigmast-5-en-3beta-ol	CHEMBL221542 CHEMBL1398443 CHEMBL1875388		17 / 19 / 12		No. 53	No. 11
C00003674	Stigmasterol / beta-Stigmasterol	CHEMBL66943 CHEMBL186373 CHEMBL400247 CHEMBL1568947	D013265	5 / 0 / 0	1 / 0	No. 53	No. 11
C00034703	Szowitsiacoumarin A / (+)-Szowitsiacoumarin A					No. 209
C00034704	Szowitsiacoumarin B / (+)-Szowitsiacoumarin B	CHEMBL270298				No. 209
C00029763	Auraptene	CHEMBL307341	C105832	28 / 25 / 26	3 / 0	No. 335
C00034380	2-Epihelmanticine					No. 1913
C00034507	Farnesiferol B	CHEMBL272886 CHEMBL1082630 CHEMBL1083019				No. 1958
C00034508	Farnesiferol C	CHEMBL177697 CHEMBL270486				No. 2027
C00034520	Galbanic acid	CHEMBL1078509	C048972			No. 2027
C00034737	Umbelliprenin	CHEMBL156127		8 / 3 / 3		No. 2038
C00034601	Methyl galbanate					No. 2552
C00034625	Persicasulfide A / (-)-Persicasulfide A					No. 8909

Human Protein / Gene in interactions

49 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
Q9NUW8	Tyrosyl-DNA phosphodiesterase 1	Enzyme	C00003672 C00029763 C00034737	1 / 1
P16050	Arachidonate 15-lipoxygenase	Enzyme	C00029763 C00034737	0 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00029763 C00034737	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003672 C00029763	0 / 1
P06746	DNA polymerase beta	Enzyme	C00003672 C00003674	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00029763 C00034737	0 / 0
O75496	Geminin	Unclassified protein	C00029763 C00034737	0 / 0
P17405	Sphingomyelin phosphodiesterase	Enzyme	C00029763 C00034737	2 / 2
P14679	Tyrosinase	Oxidoreductase	C00003672	4 / 2
P34969	5-hydroxytryptamine receptor 7	Serotonin receptor	C00003674	0 / 0
P08183	Multidrug resistance protein 1	drug	C00003672	1 / 0
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003672	0 / 1
P00352	Retinal dehydrogenase 1	Enzyme	C00029763	0 / 0
P08047	Transcription factor Sp1	Unclassified protein	C00003672	0 / 0
P39748	Flap endonuclease 1	Enzyme	C00034737	0 / 0
P84022	Mothers against decapentaplegic homolog 3	Unclassified protein	C00029763	2 / 0
Q13315	Serine-protein kinase ATM	Atypical serine/threonine protein kinase PIKK subfamily	C00029763	1 / 4
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003672	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00029763	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00029763	1 / 1
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00029763	0 / 0
P04062	Glucosylceramidase	Enzyme	C00029763	6 / 4
O94782	Ubiquitin carboxyl-terminal hydrolase 1	Enzyme	C00029763	0 / 0
P00734	Prothrombin	S1A	C00003672	4 / 2
P16473	Thyrotropin receptor	Glycohormone receptor	C00003672	3 / 2
P06280	Alpha-galactosidase A	Enzyme	C00029763	1 / 1
Q96RI1	Bile acid receptor	NR1H4	C00029763	0 / 0
P28482	Mitogen-activated protein kinase 1	Erk	C00029763	0 / 0
P56817	Beta-secretase 1	A1A	C00029763	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003672	0 / 0
Q99714	3-hydroxyacyl-CoA dehydrogenase type-2	Enzyme	C00029763	3 / 3
P15428	15-hydroxyprostaglandin dehydrogenase [NAD(+)]	Enzyme	C00029763	2 / 2
P03372	Estrogen receptor	NR3A1	C00003672	1 / 1
P09884	DNA polymerase alpha catalytic subunit	Transferase	C00003674	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003672	1 / 0
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003672	1 / 1
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003672	2 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00034737	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00029763	0 / 0
P10636	Microtubule-associated protein tau	Unclassified protein	C00029763	4 / 3
P80365	Corticosteroid 11-beta-dehydrogenase isozyme 2	Enzyme	C00003672	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00029763	0 / 0
Q96KQ7	Histone-lysine N-methyltransferase EHMT2	Enzyme	C00029763	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00003672	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00029763	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00029763	1 / 4
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003674	0 / 0
Q02880	DNA topoisomerase 2-beta	Isomerase	C00003674	0 / 0
Q13148	TAR DNA-binding protein 43	Unclassified protein	C00029763	1 / 1

4 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
1543	CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX	cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1)	C00029763
5743	PTGS2, COX-2, COX2, GRIPGHS, PGG/HS, PGHS-2, PHS-2, hCox-2	prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) (EC:1.14.99.1)	C00029763
7422	VEGFA, MVCD1, VEGF, VPF	vascular endothelial growth factor A	C00029763
10599	SLCO1B1, HBLRR, LST-1, LST1, OATP-C, OATP1B1, OATP2, OATPC, SLC21A6	solute carrier organic anion transporter family, member 1B1	C00003674

Related Diseases

Diseases related to proteins in ChEMBL interactions