| Organism name | Leucopaxillus gentianeus |
|---|---|
| Genus | Leucopaxillus |
| Family | Tricholomataceae |
| Kingdom | Fungi |
| Linked NCBI taxonomy name | Leucopaxillus gentianeus |
|---|---|
| Linked NCBI taxonomy ID | 181998 |
| Linked level | species |
| Family in NCBI taxonomy | Tricholomataceae |
|---|---|
| ID | 5351 |
| Kingdom (Superkingdom) in NCBI taxonomy | Fungi |
|---|---|
| ID | 4751 |
| Plant class | |
|---|---|
| ID |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00003683
|
Cucurbitacin B
|
CHEMBL367917
CHEMBL508185 CHEMBL507237 CHEMBL1708265 CHEMBL1728549 |
C041246
|
22 / 30 / 28 | No. 220 | No. 11 |
|
|
|
C00003685
|
Cucurbitacin D
|
CHEMBL493646
CHEMBL492404 |
C038105
|
1 / 0 / 0 | No. 220 | No. 11 |
|
|
|
C00041248
|
16-Deoxycucurbitacin B
/ (+)-16-Deoxycucurbitacin B |
CHEMBL503027
|
No. 220 | No. 11 |
|
|||
|
C00041251
|
18-Deoxyleucopaxillone A
/ (+)-18-Deoxyleucopaxillone A |
No. 3425 |
|
|||||
|
C00041631
|
Leucopaxillone B
/ (+)-Leucopaxillone B |
CHEMBL506664
|
No. 3425 |
|
||||
|
C00043672
|
Leucopaxillone A
/ (+)-Leucopaxillone A |
CHEMBL510964
|
No. 3425 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P20701 | Integrin alpha-L | Membrane receptor | C00003683 C00003685 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00003683 | 0 / 0 |
| Q13315 | Serine-protein kinase ATM | Atypical serine/threonine protein kinase PIKK subfamily | C00003683 | 1 / 4 |
| P02545 | Prelamin-A/C | Unclassified protein | C00003683 | 11 / 10 |
| P11387 | DNA topoisomerase 1 | Isomerase | C00003683 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003683 | 2 / 3 |
| Q16637 | Survival motor neuron protein | Unclassified protein | C00003683 | 4 / 1 |
| P39748 | Flap endonuclease 1 | Enzyme | C00003683 | 0 / 0 |
| P42858 | Huntingtin | Unclassified protein | C00003683 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003683 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003683 | 0 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00003683 | 1 / 1 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00003683 | 1 / 2 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003683 | 0 / 0 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003683 | 0 / 0 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003683 | 0 / 0 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003683 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003683 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003683 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003683 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003683 | 1 / 0 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00003683 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #208900 | Ataxia-telangiectasia; at |
Q13315
|
| #115200 | Cardiomyopathy, dilated, 1a; cmd1a |
P02545
|
| #212112 | Cardiomyopathy, dilated, with hypergonadotropic hypogonadism |
P02545
|
| #605588 | Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 |
P02545
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #181350 | Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 |
P02545
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #610140 | Heart-hand syndrome, slovenian type |
P02545
|
| #143100 | Huntington disease; hd |
P42858
|
| #176670 | Hutchinson-gilford progeria syndrome; hgps |
P02545
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #151660 | Lipodystrophy, familial partial, type 2; fpld2 |
P02545
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #248370 | Mandibuloacral dysplasia with type a lipodystrophy; mada |
P02545
|
| #613205 | Muscular dystrophy, congenital, lmna-related |
P02545
|
| #159001 | Muscular dystrophy, limb-girdle, type 1b; lgmd1b |
P02545
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #275210 | Restrictive dermopathy, lethal |
P02545
|
| #253300 | Spinal muscular atrophy, type i; sma1 |
Q16637
|
| #253550 | Spinal muscular atrophy, type ii; sma2 |
Q16637
|
| #253400 | Spinal muscular atrophy, type iii; sma3 |
Q16637
|
| #271150 | Spinal muscular atrophy, type iv; sma4 |
Q16637
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00264 | Charcot-Marie-Tooth disease (CMT) |
P02545
(related)
|
| H00294 | Dilated cardiomyopathy (DCM) |
P02545
(related)
|
| H00420 | Familial partial lipodystrophy (FPL) |
P02545
(related)
|
| H00563 | Emery-Dreifuss muscular dystrophy |
P02545
(related)
|
| H00590 | Congenital muscular dystrophies (CMD/MDC) |
P02545
(related)
|
| H00593 | Limb-girdle muscular dystrophy (LGMD) |
P02545
(related)
|
| H00601 | Hutchinson-Gilford progeria syndrome |
P02545
(related)
|
| H00663 | Restrictive dermopathy |
P02545
(related)
|
| H00665 | Mandibuloacral dysplasia |
P02545
(related)
|
| H01216 | Left ventricular noncompaction (LVNC) |
P02545
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00016 | Oral cancer |
P40763
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
Q13315
(related)
|
| H00064 | Ataxia telangiectasia (AT) |
Q13315
(related)
|
| H00094 | DNA repair defects |
Q13315
(related)
|
| H00848 | Ataxia with ocular apraxia (AOA) |
Q13315
(related)
|
| H00455 | Spinal muscular atrophy (SMA) |
Q16637
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|