Brucea antidysenterica
Species
KNApSAcK Entry
| Organism name | Brucea antidysenterica |
|---|---|
| Genus | Brucea |
| Family | Simaroubaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Brucea antidysenterica |
|---|---|
| Linked NCBI taxonomy ID | 459111 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Simaroubaceae |
|---|---|
| ID | 23808 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (3)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003718
|
Isobrucein B
/ isobruceine B |
CHEMBL475082
|
C076339
|
No. 704 | No. 51 |
|
||
|
C00003700
|
Bruceantinol
|
CHEMBL450145
|
No. 2130 | No. 51 |
|
|||
|
C00003699
|
Bruceantin
|
CHEMBL509895
CHEMBL1700569 |
C002550
|
12 / 12 / 8 | 0 / 1 | No. 2130 | No. 51 |
|
Human Protein / Gene in interactions
12 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P10635 | Cytochrome P450 2D6 | Cytochrome P450 2D6 | C00003699 | 1 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00003699 | 1 / 1 |
| P49798 | Regulator of G-protein signaling 4 | Unclassified protein | C00003699 | 2 / 0 |
| P37840 | Alpha-synuclein | Unclassified protein | C00003699 | 4 / 2 |
| O75496 | Geminin | Unclassified protein | C00003699 | 0 / 0 |
| P11308 | Transcriptional regulator ERG | Unclassified protein | C00003699 | 1 / 2 |
| P83916 | Chromobox protein homolog 1 | Unclassified protein | C00003699 | 0 / 0 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003699 | 0 / 0 |
| P05412 | Transcription factor AP-1 | Transcription Factor | C00003699 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003699 | 1 / 0 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00003699 | 1 / 2 |
| Q13148 | TAR DNA-binding protein 43 | Unclassified protein | C00003699 | 1 / 1 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (12)
| OMIM | preferred title | UniProt |
|---|---|---|
| #612069 | Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 |
Q13148
|
| #127750 | Dementia, lewy body; dlb |
P37840
|
| #608902 | Drug metabolism, poor, cyp2d6-related |
P10635
|
| #612219 | Ewing sarcoma; es |
P11308
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #168601 | Parkinson disease 1, autosomal dominant; park1 |
P37840
|
| #605543 | Parkinson disease 4, autosomal dominant; park4 |
P37840
|
| #168600 | Parkinson disease, late-onset; pd |
P37840
|
| #604906 | Schizophrenia 9; sczd9 |
P49798
|
| #181500 | Schizophrenia; sczd |
P49798
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
KEGG DISEASE (8)
| KEGG | name | UniProt |
|---|---|---|
| H00024 | Prostate cancer |
P11308
(related)
|
| H00035 | Ewing's sarcoma |
P11308
(related)
|
| H00057 | Parkinson's disease (PD) |
P37840
(related)
|
| H00066 | Lewy body dementia (LBD) |
P37840
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
Q13148
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|