Stenocereus eruca

• Index
• Plant Species
• Metabolite list (11)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Stenocereus eruca
Genus	Stenocereus
Family	Cactaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Stenocereus eruca
Linked NCBI taxonomy ID	867530
Linked level	species

Family

Family in NCBI taxonomy	Cactaceae
ID	3593

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	eudicotyledons
ID	71240

Metabolite list (11)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00032378	Treleasegenic acid	CHEMBL1904698		3 / 2 / 3		No. 13	No. 51
C00019064	Oleanolic acid / Astrantiagenin C / Virgaureagenin B / 3beta-Hydroxyolean-12-en-28-oic acid	CHEMBL56615 CHEMBL168 CHEMBL180553 CHEMBL365375 CHEMBL486382 CHEMBL1413646 CHEMBL1436454	D009828	30 / 8 / 12	21 / 15	No. 13	No. 51
C00031116	Queretaroic acid	CHEMBL1733823 CHEMBL1886861		4 / 0 / 0		No. 13	No. 51
C00030794	Morolic acid	CHEMBL463665		3 / 0 / 0		No. 13	No. 51
C00030702	Machaerogenin	CHEMBL1710708		1 / 0 / 0		No. 13	No. 51
C00030701	Machaeroceric acid					No. 23	No. 51
C00029446	22beta-Hydroxystellatogenin					No. 23	No. 51
C00029445	21-ketobetulinic acid					No. 23	No. 51
C00032200	Stellatogenin	CHEMBL2144823		2 / 4 / 2		No. 23	No. 51
C00032354	Thurberogenin					No. 23	No. 51
C00003741	Betulinic acid	CHEMBL269277 CHEMBL71690 CHEMBL519059 CHEMBL1318530 CHEMBL2005635	C002070	34 / 17 / 14	10 / 2	No. 23	No. 51

Human Protein / Gene in interactions

60 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00003741 C00019064 C00032200 C00032378	0 / 0
P43220	Glucagon-like peptide 1 receptor	Glucagon-like peptide receptor	C00003741 C00031116 C00032378	0 / 0
P24666	Low molecular weight phosphotyrosine protein phosphatase	Tyr	C00019064 C00030794	0 / 0
O60218	Aldo-keto reductase family 1 member B10	Enzyme	C00003741 C00019064	0 / 0
P83916	Chromobox protein homolog 1	Unclassified protein	C00019064 C00031116	0 / 0
P06746	DNA polymerase beta	Enzyme	C00003741 C00019064	0 / 0
P18031	Tyrosine-protein phosphatase non-receptor type 1	Tyr	C00019064 C00030794	0 / 0
Q96RI1	Bile acid receptor	NR1H4	C00003741 C00019064	0 / 0
Q8TDU6	G-protein coupled bile acid receptor 1	Steroid-like ligand receptor	C00003741 C00019064	0 / 0
O75604	Ubiquitin carboxyl-terminal hydrolase 2	Enzyme	C00003741 C00019064	0 / 0
P49841	Glycogen synthase kinase-3 beta	Gsk	C00003741 C00019064	0 / 0
P15121	Aldose reductase	Enzyme	C00003741 C00019064	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00019064 C00031116	0 / 0
P10586	Receptor-type tyrosine-protein phosphatase F	Receptor tyrosine-protein phosphatase	C00019064 C00030794	0 / 0
P08684	Cytochrome P450 3A4	Cytochrome P450 3A4	C00003741	0 / 1
P11712	Cytochrome P450 2C9	Cytochrome P450 2C9	C00003741	0 / 1
P15559	NAD(P)H dehydrogenase [quinone] 1	Enzyme	C00003741	0 / 0
P11387	DNA topoisomerase 1	Isomerase	C00003741	0 / 0
P11388	DNA topoisomerase 2-alpha	Isomerase	C00003741	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00032378	2 / 3
P23219	Prostaglandin G/H synthase 1	Oxidoreductase	C00019064	0 / 0
Q16665	Hypoxia-inducible factor 1-alpha	Transcription Factor	C00003741	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00019064	0 / 0
P08151	Zinc finger protein GLI1	Unclassified protein	C00003741	0 / 0
Q02156	Protein kinase C epsilon type	Eta	C00003741	0 / 0
P37840	Alpha-synuclein	Unclassified protein	C00032200	4 / 2
P02545	Prelamin-A/C	Unclassified protein	C00003741	11 / 10
Q06124	Tyrosine-protein phosphatase non-receptor type 11	Tyr	C00019064	4 / 2
P51684	C-C chemokine receptor type 6	CC chemokine receptor	C00030702	0 / 0
Q04206	Transcription factor p65	Transcription Factor	C00003741	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00003741	1 / 1
P35354	Prostaglandin G/H synthase 2	Oxidoreductase	C00019064	0 / 3
Q9HC16	DNA dC->dU-editing enzyme APOBEC-3G	Enzyme	C00003741	0 / 0
P11511	Cytochrome P450 19A1	Cytochrome P450 19A1	C00019064	2 / 2
P49798	Regulator of G-protein signaling 4	Unclassified protein	C00003741	2 / 0
Q13133	Oxysterols receptor LXR-alpha	NR1H3	C00003741	0 / 0
P18433	Receptor-type tyrosine-protein phosphatase alpha	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
P35236	Tyrosine-protein phosphatase non-receptor type 7	Tyr	C00019064	0 / 0
P05177	Cytochrome P450 1A2	Cytochrome P450 1A2	C00003741	0 / 0
P55055	Oxysterols receptor LXR-beta	NR1H3	C00003741	0 / 0
Q96QE3	ATPase family AAA domain-containing protein 5	Unclassified protein	C00019064	0 / 0
P19838	Nuclear factor NF-kappa-B p105 subunit	Transcription Factor	C00003741	0 / 0
P05771	Protein kinase C beta type	Alpha	C00003741	0 / 0
P35228	Nitric oxide synthase, inducible	Enzyme	C00019064	1 / 1
P33261	Cytochrome P450 2C19	Cytochrome P450 2C19	C00003741	1 / 1
P51452	Dual specificity protein phosphatase 3	Ser_Thr_Tyr	C00019064	0 / 0
P10635	Cytochrome P450 2D6	Cytochrome P450 2D6	C00003741	1 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00031116	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00019064	0 / 0
P17706	Tyrosine-protein phosphatase non-receptor type 2	Tyr	C00019064	0 / 1
P29350	Tyrosine-protein phosphatase non-receptor type 6	Tyr	C00019064	0 / 0
P04054	Phospholipase A2	Enzyme	C00019064	0 / 0
P23469	Receptor-type tyrosine-protein phosphatase epsilon	Receptor tyrosine-protein phosphatase	C00019064	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00003741	0 / 0
O75874	Isocitrate dehydrogenase [NADP] cytoplasmic	Enzyme	C00003741	1 / 0
Q8IUX4	DNA dC->dU-editing enzyme APOBEC-3F	Enzyme	C00003741	0 / 0
Q13951	Core-binding factor subunit beta	Unclassified protein	C00019064	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00019064	1 / 4
Q9UBT2	SUMO-activating enzyme subunit 2	Enzyme	C00003741	0 / 0
Q9UBE0	SUMO-activating enzyme subunit 1	Unclassified protein	C00003741	0 / 0

26 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
836	CASP3, CPP32, CPP32B, SCA-1	caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56)	C00003741 C00019064
7153	TOP2A, TOP2, TP2A	topoisomerase (DNA) II alpha 170kDa (EC:5.99.1.3)	C00003741 C00019064
7150	TOP1, TOPI	topoisomerase (DNA) I (EC:5.99.1.2)	C00003741 C00019064
5595	MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK	mitogen-activated protein kinase 3 (EC:2.7.11.24)	C00003741 C00019064
5594	MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk	mitogen-activated protein kinase 1 (EC:2.7.11.24)	C00003741 C00019064
595	CCND1, BCL1, D11S287E, PRAD1, U21B31	cyclin D1	C00019064
840	CASP7, CASP-7, CMH-1, ICE-LAP3, LICE2, MCH3	caspase 7, apoptosis-related cysteine peptidase (EC:3.4.22.60)	C00003741
207	AKT1, AKT, CWS6, PKB, PKB-ALPHA, PRKBA, RAC, RAC-ALPHA	v-akt murine thymoma viral oncogene homolog 1 (EC:2.7.11.1)	C00003741
332	BIRC5, API4, EPR-1	baculoviral IAP repeat containing 5	C00003741
581	BAX, BCL2L4	BCL2-associated X protein	C00003741
177	AGER, RAGE	advanced glycosylation end product-specific receptor	C00019064
841	CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5	caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61)	C00019064
847	CAT	catalase (EC:1.11.1.6)	C00019064
1956	EGFR, ERBB, ERBB1, HER1, PIG61, mENA	epidermal growth factor receptor (EC:2.7.10.1)	C00003741
1544	CYP1A2, CP12, P3-450, P450(PA)	cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1)	C00019064
1576	CYP3A4, CP33, CP34, CYP3A, CYP3A3, CYPIIIA3, CYPIIIA4, HLP, NF-25, P450C3, P450PCN1	cytochrome P450, family 3, subfamily A, polypeptide 4 (EC:1.14.13.67 1.14.13.97 1.14.13.32 1.14.13.157)	C00019064
3065	HDAC1, GON-10, HD1, RPD3, RPD3L1	histone deacetylase 1 (EC:3.5.1.98)	C00019064
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00019064
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00019064
4233	MET, AUTS9, HGFR, RCCP2, c-Met	met proto-oncogene (EC:2.7.10.1)	C00019064
4780	NFE2L2, NRF2	nuclear factor, erythroid 2-like 2	C00019064
5052	PRDX1, MSP23, NKEF-A, NKEFA, PAG, PAGA, PAGB, PRX1, PRXI, TDPX2	peroxiredoxin 1 (EC:1.11.1.15)	C00019064
5728	PTEN, 10q23del, BZS, CWS1, DEC, GLM2, MHAM, MMAC1, PTEN1, TEP1	phosphatase and tensin homolog (EC:3.1.3.67 3.1.3.16 3.1.3.48)	C00019064
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00019064
7124	TNF, DIF, TNF-alpha, TNFA, TNFSF2	tumor necrosis factor	C00019064
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00019064

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions