PCIDB

Euphorbia resinfera

Species

KNApSAcK Entry

Organism name Euphorbia resinfera
Genus Euphorbia
Family Euphorbiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Euphorbiaceae
Linked NCBI taxonomy ID 3977
Linked level family

Family

Family in NCBI taxonomy Euphorbiaceae
ID 3977

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00003745 External link 512 Euphol
/ alpha-Euphol
/ (+)-alpha-Euphol
CHEMBL225111
CHEMBL465181
CHEMBL1397369
C062557
10 / 17 / 17 No. 218 No. 51
C00033630 External link 512 Euphorbol
/ alpha-Euphorbol
/ gamma-Euphorbol
CHEMBL518556
No. 218 No. 51

Human Protein / Gene in interactions

10 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003745 0 / 0
P02545 Prelamin-A/C Unclassified protein C00003745 11 / 10
Q16850 Lanosterol 14-alpha demethylase Cytochrome P450 51A1 C00003745 0 / 0
P11473 Vitamin D3 receptor NR1I1 C00003745 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00003745 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00003745 0 / 0
P16050 Arachidonate 15-lipoxygenase Enzyme C00003745 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003745 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00003745 4 / 3
Q07869 Peroxisome proliferator-activated receptor alpha NR1C1 C00003745 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (17)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (17)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)