Species

KNApSAcK Entry

Organism name Excoecaria agallocha L.
Genus Excoecaria
Family Euphorbiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Excoecaria agallocha
Linked NCBI taxonomy ID 241838
Linked level species

Family

Family in NCBI taxonomy Euphorbiaceae
ID 3977

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003758 External link 512 Alnulin
/ Tiliadin
/ Skimmiol
/ Taraxerol
CHEMBL511822
CHEMBL470462
C005802
No. 13 No. 51
C00019226 External link 512 3-Epitaraxerol
CHEMBL511822
CHEMBL470462
No. 13 No. 51
C00032287 External link 512 Taraxerone
CHEMBL519077
CHEMBL1990874
C009379
No. 13 No. 51
C00029492 External link 512 epi-Lupeol
/ 3-Epilupeol
/ (+)-epi-Lupeol
CHEMBL289191
CHEMBL459702
3 / 0 / 0 No. 23 No. 51
C00037098 External link 512 ent-16-hydroxy-3-oxo-13-epi-manoyl oxide
/ (-)-ent-16-hydroxy-3-oxo-13-epi-manoyl oxide
No. 70
C00022654 External link 512 beta-Amyrin acetate
CHEMBL489760
CHEMBL1318082
4 / 3 / 7 No. 177

Human Protein / Gene in interactions

6 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P11387 DNA topoisomerase 1 Isomerase C00022654 C00029492 0 / 0
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00022654 0 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00029492 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00029492 0 / 0
O00255 Menin Unclassified protein C00022654 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00022654 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (3)

OMIM preferred title UniProt
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255

KEGG DISEASE (7)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)