Species

KNApSAcK Entry

Organism name Scutellaria rehderiana
Genus Scutellaria
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Scutellaria rehderiana
Linked NCBI taxonomy ID 516072
Linked level species

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003804 External link 512 Oroxylin A
CHEMBL183513
C080669
4 / 2 / 1 12 / 2 No. 3 No. 15
C00003901 External link 512 Rehderianin I
C052063
No. 3 No. 15

Human Protein / Gene in interactions

4 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08047 Transcription factor Sp1 Unclassified protein C00003804 0 / 0
P16220 Cyclic AMP-responsive element-binding protein 1 Unclassified protein C00003804 1 / 0
P36888 Receptor-type tyrosine-protein kinase FLT3 Pdgfr C00003804 1 / 1
P05412 Transcription factor AP-1 Transcription Factor C00003804 0 / 0

12 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
596 BCL2, Bcl-2, PPP1R50 B-cell CLL/lymphoma 2 C00003804
836 CASP3, CPP32, CPP32B, SCA-1 caspase 3, apoptosis-related cysteine peptidase (EC:3.4.22.56) C00003804
841 CASP8, ALPS2B, CAP4, Casp-8, FLICE, MACH, MCH5 caspase 8, apoptosis-related cysteine peptidase (EC:3.4.22.61) C00003804
842 CASP9, APAF-3, APAF3, ICE-LAP6, MCH6, PPP1R56 caspase 9, apoptosis-related cysteine peptidase (EC:3.4.22.62) C00003804
2353 FOS, AP-1, C-FOS, p55 FBJ murine osteosarcoma viral oncogene homolog C00003804
5594 MAPK1, ERK, ERK2, ERT1, MAPK2, P42MAPK, PRKM1, PRKM2, p38, p40, p41, p41mapk mitogen-activated protein kinase 1 (EC:2.7.11.24) C00003804
5595 MAPK3, ERK-1, ERK1, ERT2, HS44KDAP, HUMKER1A, P44ERK1, P44MAPK, PRKM3, p44-ERK1, p44-MAPK mitogen-activated protein kinase 3 (EC:2.7.11.24) C00003804
4313 MMP2, CLG4, CLG4A, MMP-II, MONA, TBE-1 matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase) (EC:3.4.24.24) C00003804
4318 MMP9, CLG4B, GELB, MANDP2, MMP-9 matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase) (EC:3.4.24.35) C00003804
142 PARP1, ADPRT, ADPRT_1, ADPRT1, ARTD1, PARP, PARP-1, PPOL, pADPRT-1 poly (ADP-ribose) polymerase 1 (EC:2.4.2.30) C00003804
5580 PRKCD, MAY1, PKCD, nPKC-delta protein kinase C, delta (EC:2.7.10.2 2.7.11.13) C00003804
7077 TIMP2, CSC-21K, DDC8 TIMP metallopeptidase inhibitor 2 C00003804

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (2)

OMIM preferred title UniProt
#612160 Histiocytoma, angiomatoid fibrous P16220
#601626 Leukemia, acute myeloid; aml P36888

KEGG DISEASE (1)

KEGG name UniProt
H00003 Acute myeloid leukemia (AML) P36888 (related)

Diseases related to CTD interactions

2 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D000647 Amnesia C00003804
D009362 Neoplasm Metastasis C00003804