Species

KNApSAcK Entry

Organism name Bauhinia championii
Genus Bauhinia
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Lasiobema championii
Linked NCBI taxonomy ID 228514
Linked level species

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003919 External link 512 Prosogerin E
No. 3 No. 15
C00003918 External link 512 5,7,3',4',5'-Pentamethoxyflavone
/ Tricetin 5,7,3',4',5'-pentamethyl ether
/ 5,7-Dimethoxy-2-(3,4,5-trimethoxyphenyl)-4H-1-benzopyran-4-one
CHEMBL2074901
1 / 1 / 0 No. 8 No. 15
C00003871 External link 512 5,7,3',4'-Tetramethoxyflavone
/ Luteolin 5,7,3',4'-tetramethyl ether
CHEMBL327340
C103111
1 / 0 No. 8 No. 15
C00013596 External link 512 Sinensetin
/ Pedalitin permethyl ether
/ 5,6,7,3',4'-Pentamethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5,6,7-trimethoxy-4H-1-benzopyran-4-one
CHEMBL226507
C059295
7 / 6 / 7 3 / 0 No. 8 No. 15
C00004006 External link 512 5,6,7,3'-Tetramethoxy-4',5'-methylenedioxyflavone
No. 27 No. 15
C00004002 External link 512 5,7,3'-Trimethoxy-4',5'-methylenedioxyflavone
No. 27 No. 15

Human Protein / Gene in interactions

7 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08183 Multidrug resistance protein 1 drug C00003918 C00013596 1 / 0
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00013596 2 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00013596 0 / 0
P04798 Cytochrome P450 1A1 Cytochrome P450 1A1 C00013596 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00013596 0 / 0
O00255 Menin Unclassified protein C00013596 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00013596 1 / 2

4 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1543 CYP1A1, AHH, AHRR, CP11, CYP1, P1-450, P450-C, P450DX cytochrome P450, family 1, subfamily A, polypeptide 1 (EC:1.14.14.1) C00013596
1544 CYP1A2, CP12, P3-450, P450(PA) cytochrome P450, family 1, subfamily A, polypeptide 2 (EC:1.14.14.1) C00013596
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00013596
4363 ABCC1, ABC29, ABCC, GS-X, MRP, MRP1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 C00003871

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (6)

OMIM preferred title UniProt
#614490 Blood group, junior system; jr Q9UNQ0
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#612244 Inflammatory bowel disease 13; ibd13 P08183
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0

KEGG DISEASE (7)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)