PCIDB

Sideritis mugronensis

Species

KNApSAcK Entry

Organism name Sideritis mugronensis
Genus Sideritis
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Sideritis
Linked NCBI taxonomy ID 155231
Linked level genus

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00004419 External link 512 8-Hydroxyluteolin 8-glucoside
/ Hypolaetin 8-O-beta-D-glucoside
C044475
No. 2 No. 15
C00013595 External link 512 Eupatrin
/ Anisomelin
/ Fastigenin
/ Cirsilineol
/ 5,4'-Dihydroxy-6,7,3'-trimethoxyflavone
CHEMBL487213
C057618
No. 3 No. 15
C00003932 External link 512 7-Methylsudachitin
/ 8-Methoxycirsilineol
/ 5,4'-Dihidroxy-6,7,8,3'-tetramethoxyflavone
/ 5-Hydroxy-2-(4-hydroxy-3-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL74272
No. 8 No. 15
C00003936 External link 512 Demethylnobiletin
/ 5-Hydroxy-6,7,8,3',4'-pentamethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5-hydroxy-6,7,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL75978
21 / 22 / 16 No. 8 No. 15
C00003933 External link 512 Gardenin D
/ 5,3'-Dihydroxy-6,7,8,4'-tetramethoxyflavone
/ 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-6,7,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL495821
No. 8 No. 15
C00022303 External link 512 Borjatriol
CHEMBL1986416
C039292
No. 70

Human Protein / Gene in interactions

21 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
O75604 Ubiquitin carboxyl-terminal hydrolase 2 Enzyme C00003936 0 / 0
P02545 Prelamin-A/C Unclassified protein C00003936 11 / 10
P00352 Retinal dehydrogenase 1 Enzyme C00003936 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00003936 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003936 0 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00003936 4 / 3
Q13748 Tubulin alpha-3C/D chain Structural C00003936 0 / 0
P68366 Tubulin alpha-4A chain Structural C00003936 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00003936 1 / 0
P04350 Tubulin beta-4A chain Structural C00003936 2 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00003936 0 / 0
P07437 Tubulin beta chain Structural C00003936 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00003936 1 / 1
P68371 Tubulin beta-4B chain Structural C00003936 0 / 0
Q13509 Tubulin beta-3 chain Structural C00003936 2 / 1
P68363 Tubulin alpha-1B chain Unclassified protein C00003936 0 / 0
Q13885 Tubulin beta-2A chain Structural C00003936 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00003936 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00003936 0 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00003936 0 / 0
Q9BVA1 Tubulin beta-2B chain Structural C00003936 1 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (22)

OMIM preferred title UniProt
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#600274 Frontotemporal dementia; ftd P10636
#610140 Heart-hand syndrome, slovenian type P02545
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#275210 Restrictive dermopathy, lethal P02545
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (16)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)