PCIDB

Campylotropis hirtella (FRANCH.) SCHNDL

Species

KNApSAcK Entry

Organism name Campylotropis hirtella (FRANCH.) SCHNDL
Genus Campylotropis
Family Fabaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Campylotropis
Linked NCBI taxonomy ID 53849
Linked level genus

Family

Family in NCBI taxonomy Fabaceae
ID 3803

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00002448 External link 512 Alloimperatorin
No. 606 No. 25
C00000583 External link 512 Isopimpinellin
CHEMBL140796
C015304
9 / 3 / 4 2 / 0 No. 606 No. 25
C00000575 External link 512 Bergaptan
CHEMBL24171
C022909
22 / 22 / 17 0 / 3 No. 1282 No. 25
C00029297 External link 512 Columbianetin
/ (+)-Columbianetin
CHEMBL201152
7 / 12 / 8 No. 1336 No. 25
C00029686 External link 512 Angelol B
CHEMBL1878168
No. 3091
C00029687 External link 512 Angelol G
CHEMBL1555302
4 / 0 / 0 No. 3091

Human Protein / Gene in interactions

33 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
B2RXH2 Lysine-specific demethylase 4E Enzyme C00000575 C00000583 C00029297 0 / 0
P56817 Beta-secretase 1 A1A C00000575 C00000583 C00029297 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00000575 C00000583 0 / 1
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00000575 C00000583 0 / 0
P15428 15-hydroxyprostaglandin dehydrogenase [NAD(+)] Enzyme C00000583 C00029297 2 / 2
P00352 Retinal dehydrogenase 1 Enzyme C00000575 C00029297 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00000575 C00029297 7 / 3
Q92830 Histone acetyltransferase KAT2A Enzyme C00000583 0 / 0
P17658 Potassium voltage-gated channel subfamily A member 6 K C00000575 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00000575 3 / 2
P08183 Multidrug resistance protein 1 drug C00000575 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00000575 0 / 1
P16389 Potassium voltage-gated channel subfamily A member 2 KCNA, Kv1.x (Shaker) C00000575 0 / 0
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00000575 1 / 0
P17405 Sphingomyelin phosphodiesterase Enzyme C00029297 2 / 2
P11509 Cytochrome P450 2A6 Cytochrome P450 2A6 C00000575 0 / 0
P20813 Cytochrome P450 2B6 Cytochrome P450 2B6 C00000575 1 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00029687 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00000575 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00029297 1 / 1
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00000575 3 / 3
P22001 Potassium voltage-gated channel subfamily A member 3 KCNA, Kv1.x (Shaker) C00000575 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00029687 0 / 0
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00000575 1 / 1
P06746 DNA polymerase beta Enzyme C00000583 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00029687 0 / 0
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00000583 0 / 0
P48547 Potassium voltage-gated channel subfamily C member 1 K C00000575 0 / 0
P10275 Androgen receptor NR3C4 C00000575 3 / 4
P22460 Potassium voltage-gated channel subfamily A member 5 KCNA, Kv1.x (Shaker) C00000575 1 / 1
Q9UBT6 DNA polymerase kappa Enzyme C00029687 0 / 0
Q09470 Potassium voltage-gated channel subfamily A member 1 KCNA, Kv1.x (Shaker) C00000575 1 / 1
Q13148 TAR DNA-binding protein 43 Unclassified protein C00000583 1 / 1

2 Gene in CTD interactions

gene gene name gene description KNApSAcK metabolite in interactions
1545 CYP1B1, CP1B, CYPIB1, GLC3A, P4501B1 cytochrome P450, family 1, subfamily B, polypeptide 1 (EC:1.14.14.1) C00000583
8856 NR1I2, BXR, ONR1, PAR, PAR1, PAR2, PARq, PRR, PXR, SAR, SXR nuclear receptor subfamily 1, group I, member 2 C00000583

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (28)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#300068 Androgen insensitivity syndrome; ais P10275
#312300 Androgen insensitivity, partial; pais P10275
#612240 Atrial fibrillation, familial, 7; atfb7 P22460
#119900 Digital clubbing, isolated congenital P15428
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#614546 Efavirenz, poor metabolism of P20813
#160120 Episodic ataxia, type 1; ea1 Q09470
#232300 Glycogen storage disease ii P10253
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#259100 Hypertrophic osteoarthropathy, primary, autosomal recessive, 1; phoar1 P15428
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#174800 Mccune-albright syndrome; mas P63092
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#257200 Niemann-pick disease, type a P17405
#607616 Niemann-pick disease, type b P17405
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#313200 Spinal and bulbar muscular atrophy, x-linked 1; smax1 P10275

KEGG DISEASE (23)

KEGG name UniProt
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00024 Prostate cancer P10275 (related)
H00062 Spinal and bulbar muscular atrophy (SBMA) P10275 (related)
H00608 46,XY disorders of sex development (Disorders in androgen synthesis or action) P10275 (related)
H00609 46,XY disorders of sex development (Other) P10275 (related)
H01205 Coumarin resistance P11712 (related)
H00457 Primary hypertrophic osteoarthropathy (PHO) P15428 (related)
H01246 Isolated congenital nail clubbing (ICNC) P15428 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00137 Niemann-Pick disease (NPD) typeA and B P17405 (related)
H00424 Defects in the degradation of sphingomyelin P17405 (related)
H00731 Atrial fibrillation P22460 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00749 Episodic ataxias Q09470 (related)
H00058 Amyotrophic lateral sclerosis (ALS) Q13148 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)

Diseases related to CTD interactions

3 disease in interactions with metabolites

MESH or OMIM name KNApSAcK
metabolite
D006505 Hepatitis C00000575
D010787 Photosensitivity Disorders C00000575
D011565 Psoriasis C00000575