Diosma crenulata
Species
KNApSAcK Entry
| Organism name | Diosma crenulata |
|---|---|
| Genus | Diosma |
| Family | Rutaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Diosma |
|---|---|
| Linked NCBI taxonomy ID | 378921 |
| Linked level | genus |
Family
| Family in NCBI taxonomy | Rutaceae |
|---|---|
| ID | 23513 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | rosids |
|---|---|
| ID | 71275 |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00004362
|
Diosmin
/ Luteolin 4'-methyl ether 7-rutinoside / 5,7,3'-Trihydroxy-4'-methoxyflavone 7-O-rutinoside |
CHEMBL231884
CHEMBL1512770 CHEMBL1707291 |
D004145
|
20 / 8 / 14 | 1 / 5 | No. 1 | No. 15 |
|
Human Protein / Gene in interactions
20 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P06746 | DNA polymerase beta | Enzyme | C00004362 | 0 / 0 |
| Q13526 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Enzyme | C00004362 | 0 / 0 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00004362 | 2 / 3 |
| P00352 | Retinal dehydrogenase 1 | Enzyme | C00004362 | 0 / 0 |
| P39748 | Flap endonuclease 1 | Enzyme | C00004362 | 0 / 0 |
| Q92830 | Histone acetyltransferase KAT2A | Enzyme | C00004362 | 0 / 0 |
| O75496 | Geminin | Unclassified protein | C00004362 | 0 / 0 |
| P40763 | Signal transducer and activator of transcription 3 | Transcription Factor | C00004362 | 1 / 2 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00004362 | 1 / 1 |
| Q03164 | Histone-lysine N-methyltransferase 2A | Enzyme | C00004362 | 1 / 2 |
| O94782 | Ubiquitin carboxyl-terminal hydrolase 1 | Enzyme | C00004362 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00004362 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00004362 | 0 / 0 |
| O75164 | Lysine-specific demethylase 4A | Enzyme | C00004362 | 0 / 0 |
| P27695 | DNA-(apurinic or apyrimidinic site) lyase | Enzyme | C00004362 | 0 / 0 |
| Q9UBT6 | DNA polymerase kappa | Enzyme | C00004362 | 0 / 0 |
| B2RXH2 | Lysine-specific demethylase 4E | Enzyme | C00004362 | 0 / 0 |
| Q9NUW8 | Tyrosyl-DNA phosphodiesterase 1 | Enzyme | C00004362 | 1 / 1 |
| O00255 | Menin | Unclassified protein | C00004362 | 2 / 5 |
| O94925 | Glutaminase kidney isoform, mitochondrial | Enzyme | C00004362 | 0 / 0 |
1 Gene in CTD interactions
| gene | gene name | gene description | KNApSAcK metabolite in interactions |
|---|---|---|---|
| 196 | AHR, bHLHe76 | aryl hydrocarbon receptor |
C00004362
|
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (8)
| OMIM | preferred title | UniProt |
|---|---|---|
| #605130 | Hairy elbows, short stature, facial dysmorphism, and developmental delay |
Q03164
|
| #147060 | Hyper-ige recurrent infection syndrome, autosomal dominant |
P40763
|
| #145000 | Hyperparathyroidism 1; hrpt1 |
O00255
|
| #131100 | Multiple endocrine neoplasia, type i; men1 |
O00255
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #607250 | Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 |
Q9NUW8
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
KEGG DISEASE (14)
| KEGG | name | UniProt |
|---|---|---|
| H00033 | Adrenal carcinoma |
O00255
(related)
|
| H00034 | Carcinoid |
O00255
(related)
|
| H00045 | Malignant islet cell carcinoma |
O00255
(related)
|
| H00246 | Primary hyperparathyroidism |
O00255
(related)
|
| H01102 | Pituitary adenomas |
O00255
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00016 | Oral cancer |
P40763
(related)
|
| H00107 | Other well-defined immunodeficiency syndromes |
P40763
(related)
|
| H00001 | Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) |
Q03164
(related)
Q03164 (marker) |
| H00002 | Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) |
Q03164
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q9NUW8
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|