Species

KNApSAcK Entry

Organism name Alpinia flabellata Ridley
Genus Alpinia
Family Zingiberaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Zingiberaceae
Linked NCBI taxonomy ID 4642
Linked level family

Family

Family in NCBI taxonomy Zingiberaceae
ID 4642

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (5)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004571 External link 512 Kaempferol 7,4'-dimethyl ether
/ 3,5-Dihydroxy-7,4'-dimethoxyflavone
/ 3,5-Dihydroxy-7-methoxy-2-(4-methoxyphenyl)-4H-1-benzopyran-4-one
No. 3 No. 15
C00036457 External link 512 2,4,5-Trimethoxycinnamaldehyde
CHEMBL1163242
No. 723 No. 6
C00036456 External link 512 2,4,5-Trimethoxybenzaldehyde
/ 3,4,6-Trimethoxybenzaldehyde
CHEMBL1164301
C034031
9 / 14 / 7 No. 856
C00040748 External link 512 (+/-)-trans-3-(2,4,5-Trimethoxyphenyl)-4-[(E)-2,4,5-trimethoxystyryl]-cyclohexene
No. 951 No. 21
C00040868 External link 512 Alflabene
No. 951 No. 21

Human Protein / Gene in interactions

9 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q03181 Peroxisome proliferator-activated receptor delta NR1C2 C00036456 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00036456 3 / 2
P10828 Thyroid hormone receptor beta NR1A2 C00036456 3 / 1
P00352 Retinal dehydrogenase 1 Enzyme C00036456 0 / 0
P63092 Guanine nucleotide-binding protein G(s) subunit alpha isoforms short Other membrane protein C00036456 7 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00036456 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00036456 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00036456 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00036456 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#219080 Acth-independent macronodular adrenal hyperplasia; aimah P63092
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#174800 Mccune-albright syndrome; mas P63092
#166350 Osseous heteroplasia, progressive; poh P63092
#102200 Pituitary adenoma, growth hormone-secreting P63092
#103580 Pseudohypoparathyroidism, type ia; php1a P63092
#603233 Pseudohypoparathyroidism, type ib; php1b P63092
#612462 Pseudohypoparathyroidism, type ic; php1c P63092
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#188570 Thyroid hormone resistance, generalized, autosomal dominant; grth P10828
#274300 Thyroid hormone resistance, generalized, autosomal recessive; grth P10828
#145650 Thyroid hormone resistance, selective pituitary; prth P10828

KEGG DISEASE (7)

KEGG name UniProt
H00249 Thyroid hormone resistance syndrome P10828 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00244 Pseudohypoparathyroidism P63092 (related)
H00441 Progressive osseous heteroplasia (POH) P63092 (related)
H00501 Fibrous dysplasia, polyostotic P63092 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)