Species

KNApSAcK Entry

Organism name Polanisia trachysperma
Genus Polanisia
Family Cleomaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Polanisia
Linked NCBI taxonomy ID 72659
Linked level genus

Family

Family in NCBI taxonomy Cleomaceae
ID 301454

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class rosids
ID 71275

Metabolite list (6)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00004727 External link 512 Gossypetin 3,8-dimethyl ether
/ 5,7,3',4'-Tetrahydroxy-3,8-dimethoxyflavone
/ 2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-3,8-dimethoxy-4H-1-benzopyran-4-one
CHEMBL162550
No. 3 No. 15
C00004735 External link 512 Gossypetin 3,8,3'-trimethyl ether
/ 5,7,4'-Trihydroxy-3,8,3'-trimethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,8-dimethoxy-4H-1-benzopyran-4-one
CHEMBL1985918
No. 3 No. 15
C00004794 External link 512 5,7,4'-Trihydroxy-3,6,8,3'-tetramethoxyflavone
/ 5,7-Dihydroxy-2-(4-hydroxy-3-methoxyphenyl)-3,6,8-trimethoxy-4H-1-benzopyran-4-one
CHEMBL77156
15 / 7 / 2 No. 8 No. 15
C00004673 External link 512 5-Hydroxyauranetin
/ 5-Hydroxy-3,6,7,8,4'-pentamethoxyflavone
/ 5-Hydroxy-3,6,7,8-tetramethoxy-2-(4-methoxyphenyl)-4H-1-Benzopyran-4-one
CHEMBL504047
No. 8 No. 15
C00004800 External link 512 5,3'-Dihydroxy-3,6,7,8,4'-pentamethoxyflavone
/ 5-Hydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
CHEMBL18351
15 / 7 / 2 No. 8 No. 15
C00004802 External link 512 5-Hydroxy-3,6,7,8,3'4'-hexamethoxyflavone
/ 2-(3,4-Dimethoxyphenyl)-5-hydroxy-3,6,7,8-tetramethoxy-4H-1-benzopyran-4-one
CHEMBL422237
26 / 14 / 6 No. 8 No. 15

Human Protein / Gene in interactions

26 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q9BVA1 Tubulin beta-2B chain Structural C00004794 C00004800 C00004802 1 / 0
Q9BUF5 Tubulin beta-6 chain Structural C00004794 C00004800 C00004802 0 / 0
Q9BQE3 Tubulin alpha-1C chain Unclassified protein C00004794 C00004800 C00004802 0 / 0
Q6PEY2 Tubulin alpha-3E chain Unclassified protein C00004794 C00004800 C00004802 0 / 0
Q13885 Tubulin beta-2A chain Structural C00004794 C00004800 C00004802 0 / 0
P68363 Tubulin alpha-1B chain Unclassified protein C00004794 C00004800 C00004802 0 / 0
Q13509 Tubulin beta-3 chain Structural C00004794 C00004800 C00004802 2 / 1
P68371 Tubulin beta-4B chain Structural C00004794 C00004800 C00004802 0 / 0
Q71U36 Tubulin alpha-1A chain Structural C00004794 C00004800 C00004802 1 / 1
P07437 Tubulin beta chain Structural C00004794 C00004800 C00004802 0 / 0
Q13748 Tubulin alpha-3C/D chain Structural C00004794 C00004800 C00004802 0 / 0
P68366 Tubulin alpha-4A chain Structural C00004794 C00004800 C00004802 0 / 0
Q9H4B7 Tubulin beta-1 chain Structural C00004794 C00004800 C00004802 1 / 0
Q3ZCM7 Tubulin beta-8 chain Structural C00004794 C00004800 C00004802 0 / 0
P04350 Tubulin beta-4A chain Structural C00004794 C00004800 C00004802 2 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00004802 0 / 0
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00004802 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00004802 4 / 3
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00004802 0 / 0
Q13148 TAR DNA-binding protein 43 Unclassified protein C00004802 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00004802 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00004802 0 / 0
O75496 Geminin Unclassified protein C00004802 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00004802 1 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00004802 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00004802 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (14)

OMIM preferred title UniProt
#612069 Amyotrophic lateral sclerosis 10, with or without frontotemporal dementia; als10 Q13148
#614039 Cortical dysplasia, complex, with other brain malformations 1; cdcbm1 Q13509
#128101 Dystonia 4, torsion, autosomal dominant; dyt4 P04350
#600638 Fibrosis of extraocular muscles, congenital, 3a, with or without extraocular involvement; cfeom3a Q13509
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#612438 Leukodystrophy, hypomyelinating, 6; hld6 P04350
#611603 Lissencephaly 3; lis3 Q71U36
#613112 Macrothrombocytopenia, autosomal dominant, tubb1-related Q9H4B7
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#610031 Polymicrogyria, symmetric or asymmetric; pmgysa Q9BVA1
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (6)

KEGG name UniProt
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
Q13148 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00838 Congenital fibrosis of the extraocular muscles (CFEOM) Q13509 (related)
H00268 Lissencephaly (LIS) Q71U36 (related)