Species

KNApSAcK Entry

Organism name Aristolochia foveolata
Genus Aristolochia
Family Aristolochiaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Aristolochia foveolata
Linked NCBI taxonomy ID 158544
Linked level species

Family

Family in NCBI taxonomy Aristolochiaceae
ID 16727

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Magnoliophyta
ID 3398

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00005548 External link 512 Narcissin
/ Isorhamnetin 3-O-rutinoside
CHEMBL84174
CHEMBL258394
CHEMBL1711509
CHEMBL2165403
C031062
7 / 1 / 2 No. 1 No. 15
C00005149 External link 512 Populnin
/ Kaempferol 7-glucoside
CHEMBL469441
CHEMBL1159471
No. 2 No. 15
C00025787 External link 512 Cepharadione A
CHEMBL235921
No. 125
C00027121 External link 512 Aristolactam AII
/ Aristololactam A II
CHEMBL390368
No. 125
C00027520 External link 512 Aristolochic acid VIIa
/ 7-Hydroxyaristolochate A
/ 7-Hydroxyaristolochic acid
/ 7-Hydroxyaristolochic acid I
/ 7-Hydroxy-aristolochic acid A
CHEMBL600828
1 / 0 / 0 No. 291 No. 4
C00032730 External link 512 Aristolochate I
CHEMBL93353
13 / 11 / 12 No. 291 No. 4
C00032729 External link 512 Aristolochate C
/ Aristolochate IIIa
CHEMBL603494
1 / 0 / 0 No. 291 No. 4
C00030768 External link 512 Methyl vanillate
CHEMBL486214
No. 1936

Human Protein / Gene in interactions

17 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P24941 Cyclin-dependent kinase 2 Cdc2 C00027520 C00032729 C00032730 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00005548 C00032730 0 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005548 C00032730 0 / 1
O75496 Geminin Unclassified protein C00005548 C00032730 0 / 0
P03372 Estrogen receptor NR3A1 C00005548 1 / 1
P07237 Protein disulfide-isomerase Enzyme C00005548 0 / 0
Q16637 Survival motor neuron protein Unclassified protein C00032730 4 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00005548 0 / 0
P00352 Retinal dehydrogenase 1 Enzyme C00032730 0 / 0
Q13526 Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 Enzyme C00032730 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00005548 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00032730 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00032730 0 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00032730 0 / 0
O00255 Menin Unclassified protein C00032730 2 / 5
Q03164 Histone-lysine N-methyltransferase 2A Enzyme C00032730 1 / 2
O94925 Glutaminase kidney isoform, mitochondrial Enzyme C00032730 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (12)

OMIM preferred title UniProt
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#605130 Hairy elbows, short stature, facial dysmorphism, and developmental delay Q03164
#145000 Hyperparathyroidism 1; hrpt1 O00255
#131100 Multiple endocrine neoplasia, type i; men1 O00255
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636

KEGG DISEASE (13)

KEGG name UniProt
H00033 Adrenal carcinoma O00255 (related)
H00034 Carcinoid O00255 (related)
H00045 Malignant islet cell carcinoma O00255 (related)
H00246 Primary hyperparathyroidism O00255 (related)
H01102 Pituitary adenomas O00255 (related)
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00001 Acute lymphoblastic leukemia (ALL) (precursor B lymphoblastic leukemia) Q03164 (related)
Q03164 (marker)
H00002 Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia) Q03164 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)