Nicotiana spp.

• Index
• Plant Species
• Metabolite list (10)
• Human Protein
  / Gene in interactions
• Related Diseases

Species

KNApSAcK Entry

Organism name	Nicotiana spp.
Genus	Nicotiana
Family	Solanaceae
Kingdom	Plantae

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NCBI taxonomy

Entry

Linked NCBI taxonomy name	Nicotiana
Linked NCBI taxonomy ID	4085
Linked level	genus

Family

Family in NCBI taxonomy	Solanaceae
ID	4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy	Viridiplantae
ID	33090

Plant class

Plant class	asterids
ID	71274

Metabolite list (10)

KNApSAcK ID	name	ChEMBL link	CTD link	# of proteins in ChEMBL interaction / related OMIM / related KEGG DISEASE	# of genes in CTD interaction / related diseases	KCF-S cluster	phytochemical cluster	figure
C00005165	Sophoraflavonoloside / Kaempferol 3-O-sophoroside / Kaempferol 3-O-beta-sophoroside	CHEMBL500233 CHEMBL1375795 CHEMBL2032411	C064309	12 / 2 / 2	6 / 4	No. 1	No. 15
C00005169	Nicotiflorin / Nicotifloroside / Kaempferol 3-O-rutinoside / Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside / (-)-Kaempferol 3-O-(alpha-L-rhamnopyranosyl(1->6)-beta-D-glucopyranoside	CHEMBL431610 CHEMBL79790 CHEMBL255020 CHEMBL501550 CHEMBL498879 CHEMBL1419228 CHEMBL1875691		22 / 10 / 12		No. 1	No. 15
C00005409	Quercetin 3-O-sophoroside	CHEMBL452919	C055545			No. 1	No. 15
C00005229	(-)-Kaempferol 3-O-sophoroside 7-O-beta-D-glucopyranoside / Kaempferol 3-O-sophoroside 7-O-beta-D-glucopyranoside:Kaempferol 3-sophoroside-7-glucoside					No. 5	No. 15
C00005225	Kaempferol 3-robinobioside-7-glucoside					No. 5	No. 15
C00005222	Kaempferol 3-glucosyl-(1->2)-galactoside-7-glucoside / 3-[(2-O-beta-D-Glucopyranosyl-beta-D-galactopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one					No. 5	No. 15
C00005239	Kaempferol 3-rutinoside-7-glucoside					No. 5	No. 15
C00005219	Clitorin / Kaempferol 3-(2G-rhamnosylrutinoside)	CHEMBL362593 CHEMBL1454324 CHEMBL2005346	C077190	1 / 0 / 0		No. 5	No. 15
C00005456	Manghaslin / Quercetin 3-2G-rhamnosylrutinoside	CHEMBL444468				No. 5	No. 15
C00005464	Quercetin 3-sophoroside-7-glucoside / 2-(3,4-Dihydroxyphenyl)-3-[(2-O-beta-D-glucopyranosyl-beta-D-glucopyranosyl)oxy]-7-(beta-D-glucopyranosyloxy)-5-hydroxy-4H-1-benzopyran-4-one					No. 5	No. 15

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession	description	class description	KNApSAcK metabolite in interactions	# of diseases (OMIM / KEGG)
O75496	Geminin	Unclassified protein	C00005165 C00005169	0 / 0
P46063	ATP-dependent DNA helicase Q1	Enzyme	C00005165 C00005169	0 / 0
P06746	DNA polymerase beta	Enzyme	C00005165 C00005169	0 / 0
P10253	Lysosomal alpha-glucosidase	Hydrolase	C00005165 C00005169	1 / 1
Q13526	Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	Enzyme	C00005165 C00005169	0 / 0
Q9UBT6	DNA polymerase kappa	Enzyme	C00005165 C00005169	0 / 0
P27695	DNA-(apurinic or apyrimidinic site) lyase	Enzyme	C00005165 C00005169	0 / 0
Q9UNA4	DNA polymerase iota	Enzyme	C00005165 C00005169	0 / 0
Q9Y253	DNA polymerase eta	Enzyme	C00005165 C00005169	1 / 1
P39748	Flap endonuclease 1	Enzyme	C00005165 C00005169	0 / 0
Q9UIF8	Bromodomain adjacent to zinc finger domain protein 2B	Unclassified protein	C00005169	0 / 0
Q92830	Histone acetyltransferase KAT2A	Enzyme	C00005165	0 / 0
P11473	Vitamin D3 receptor	NR1I1	C00005169	2 / 3
P11387	DNA topoisomerase 1	Isomerase	C00005219	0 / 0
Q9Y468	Lethal(3)malignant brain tumor-like protein 1	Unclassified protein	C00005169	0 / 0
Q9NR56	Muscleblind-like protein 1	Unclassified protein	C00005169	1 / 0
O75164	Lysine-specific demethylase 4A	Enzyme	C00005169	0 / 0
P07237	Protein disulfide-isomerase	Enzyme	C00005169	0 / 0
P47989	Xanthine dehydrogenase/oxidase	Oxidoreductase	C00005169	1 / 1
B2RXH2	Lysine-specific demethylase 4E	Enzyme	C00005165	0 / 0
Q99700	Ataxin-2	Unclassified protein	C00005169	1 / 1
Q13951	Core-binding factor subunit beta	Unclassified protein	C00005169	0 / 1
Q01196	Runt-related transcription factor 1	Unclassified protein	C00005169	1 / 4
O94925	Glutaminase kidney isoform, mitochondrial	Enzyme	C00005169	0 / 0
Q14191	Werner syndrome ATP-dependent helicase	Enzyme	C00005169	2 / 1

6 Gene in CTD interactions

gene	gene name	gene description	KNApSAcK metabolite in interactions
3146	HMGB1, HMG1, HMG3, SBP-1	high mobility group box 1	C00005165
3383	ICAM1, BB2, CD54, P3.58	intercellular adhesion molecule 1	C00005165
6401	SELE, CD62E, ELAM, ELAM1, ESEL, LECAM2	selectin E	C00005165
7097	TLR2, CD282, TIL4	toll-like receptor 2	C00005165
7099	TLR4, ARMD10, CD284, TLR-4, TOLL	toll-like receptor 4	C00005165
7412	VCAM1, CD106, INCAM-100	vascular cell adhesion molecule 1	C00005165

Related Diseases

Diseases related to proteins in ChEMBL interactions

Diseases related to CTD interactions