PCIDB

Physalis angulata L.

Species

KNApSAcK Entry

Organism name Physalis angulata L.
Genus Physalis
Family Solanaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Physalis angulata
Linked NCBI taxonomy ID 113208
Linked level species

Family

Family in NCBI taxonomy Solanaceae
ID 4070

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Natural Activity

List (31)

Species Activity
Physalis angulata L. Acaricide
Physalis angulata L. Analgesic
Physalis angulata L. Anthelmintic
Physalis angulata L. Antiedemic
Physalis angulata L. Antiinflammatory
Physalis angulata L. Antileukemic
Physalis angulata L. Antilymphomic
Physalis angulata L. Antiseptic
Physalis angulata L. Antispasmodic
Physalis angulata L. Antitumor
Physalis angulata L. Antiviral
Physalis angulata L. Bactericide
Physalis angulata L. Cytotoxic
Physalis angulata L. Depurative
Physalis angulata L. Diuretic
Physalis angulata L. Expectorant
Physalis angulata L. Gram(-)-icide
Physalis angulata L. Gram(+)-icide
Physalis angulata L. Hypoglycemic
Physalis angulata L. Hypotensive
Physalis angulata L. Immunomodulator
Physalis angulata L. Immunostimulant
Physalis angulata L. Insecticide
Physalis angulata L. Molluscacide
Physalis angulata L. Myocontractant
Physalis angulata L. Narcotic
Physalis angulata L. RT-Inhibitor
Physalis angulata L. Topoisomerase-II-Inducer
Physalis angulata L. Topoisomerase-II-Inhibitor
Physalis angulata L. Tranquilizer
Physalis angulata L. Vermifuge

Metabolite list (8)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE 		# of genes in
CTD interaction
/ related diseases 		KCF-S
cluster 		phytochemical
cluster 		figure
C00005401 External link 512 Quercetin 3-robinoside
/ Quercetin 3-O-robinoside
/ Quercetin 3-O-robinobioside
/ Quercetin 3-O-rhamnosyl-(1->6)-galactoside
CHEMBL32579
CHEMBL310754
CHEMBL182108
CHEMBL226335
CHEMBL502782
CHEMBL1436093
CHEMBL1532989
25 / 18 / 16 No. 1 No. 15
C00031020 External link 512 Physagulin L
/ (+)-Physagulin L
No. 176 No. 58
C00032511 External link 512 Withangulatin I
/ (-)-Withangulatin I
No. 729
C00031021 External link 512 Physagulin M
/ (+)-Physagulin M
No. 729
C00032510 External link 512 Withangulatin A
C059043
No. 729
C00031022 External link 512 Physagulin N
/ (+)-Physagulin N
No. 729
C00031019 External link 512 Physagulin D
No. 1828
C00032512 External link 512 Withanolide
No. 6983

Human Protein / Gene in interactions

25 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P33527 Multidrug resistance-associated protein 1 drugs C00005401 0 / 0
P35354 Prostaglandin G/H synthase 2 Oxidoreductase C00005401 0 / 3
P06746 DNA polymerase beta Enzyme C00005401 0 / 0
P10253 Lysosomal alpha-glucosidase Hydrolase C00005401 1 / 1
P47989 Xanthine dehydrogenase/oxidase Oxidoreductase C00005401 1 / 1
P18825 Alpha-2C adrenergic receptor Adrenergic receptor C00005401 0 / 0
Q9NR56 Muscleblind-like protein 1 Unclassified protein C00005401 1 / 0
P11388 DNA topoisomerase 2-alpha Isomerase C00005401 0 / 0
P08913 Alpha-2A adrenergic receptor Adrenergic receptor C00005401 0 / 0
P27487 Dipeptidyl peptidase 4 S9B C00005401 0 / 1
O94782 Ubiquitin carboxyl-terminal hydrolase 1 Enzyme C00005401 0 / 0
P14679 Tyrosinase Oxidoreductase C00005401 4 / 2
P06276 Cholinesterase Hydrolase C00005401 0 / 0
P28482 Mitogen-activated protein kinase 1 Erk C00005401 0 / 0
Q99714 3-hydroxyacyl-CoA dehydrogenase type-2 Enzyme C00005401 3 / 3
Q9UNQ0 ATP-binding cassette sub-family G member 2 ATP binding cassette C00005401 2 / 0
P03372 Estrogen receptor NR3A1 C00005401 1 / 1
P22303 Acetylcholinesterase Hydrolase C00005401 1 / 0
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00005401 0 / 1
P27695 DNA-(apurinic or apyrimidinic site) lyase Enzyme C00005401 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00005401 4 / 3
P48147 Prolyl endopeptidase S9A C00005401 0 / 0
Q9UBT6 DNA polymerase kappa Enzyme C00005401 0 / 0
B2RXH2 Lysine-specific demethylase 4E Enzyme C00005401 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00005401 0 / 0

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (18)

OMIM preferred title UniProt
#300438 17-beta-hydroxysteroid dehydrogenase x deficiency Q99714
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#614490 Blood group, junior system; jr Q9UNQ0
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#232300 Glycogen storage disease ii P10253
#300705 Mental retardation, x-linked 17; mrx17 Q99714
#300220 Mental retardation, x-linked, syndromic 10; mrxs10 Q99714
#160900 Myotonic dystrophy 1; dm1 Q9NR56
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#138900 Uric acid concentration, serum, quantitative trait locus 1; uaqtl1 Q9UNQ0
#278300 Xanthinuria, type i P47989
#112100 Yt blood group antigen P22303

KEGG DISEASE (16)

KEGG name UniProt
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00069 Glycogen storage diseases (GSD) P10253 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00032 Thyroid cancer P27487 (marker)
H00017 Esophageal cancer P35354 (related)
H00025 Penile cancer P35354 (related)
H00046 Cholangiocarcinoma P35354 (related)
H00192 Xanthinuria P47989 (related)
H00480 Non-syndromic X-linked mental retardation Q99714 (related)
H00658 Syndromic X-linked mental retardation Q99714 (related)
H00925 2-Methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD) deficiency Q99714 (related)